The disclosure relates to a receiving unit configured for acquiring MR signals from an examination object in a magnetic resonance device. The receiving unit may include a detector unit comprising a light source and a first optical detector, a sensor unit comprising a first optical magnetometer, a first optical waveguide connecting the sensor unit to the light source, and a second optical waveguide connecting the sensor unit to the first optical detector.

The present application discloses methods and apparatus for detecting a complex including an analyte that include contacting a sample in a solution with a population of functionalized beads of a first type, which are magnetic functionalized beads and are functionalized to include a first moiety that associates with an analyte under suitable conditions, contacting the sample solution with a population of functionalized beads of a second type, which are functionalized to include a second moiety that associates with the analyte under suitable conditions, contact resulting in formation of a complex including one of the first type of functionalized bead, the analyte, and one of the second type of functionalized bead, and detecting the complex including the analyte by detecting magnetic fields produced by the magnetic functionalized bead and by detecting the functionalized bead of the second type associated with the analyte in the complex.

The magnetic resonance member 1 is a member that is arranged in a measurement target AC physical field, and in which a quantum operation can be performed in a specific quantum system. The coil 2 and the high frequency power supply 3 apply a magnetic field of a microwave to the magnetic resonance member 1. The irradiating device 4 irradiates the magnetic resonance member 1 with light, and the detecting device 5 detects from the magnetic resonance member 1 a physical phenomenon corresponding to the measurement target AC physical field. Further, the measurement control unit 21 performs the DC physical field measurement sequence a predetermined plural times, and in each of the plural times of the DC physical field measurement sequence, determines a detection value of the physical phenomenon detected by the detecting device 5.

The calculation unit 22 calculates a measurement result for a specific time span of the measurement target AC physical field on the basis of the detection values corresponding to the plural times of the DC physical field measurement sequence.

The present disclosure relates to a pH-sensor for determining and/or monitoring a pH value of a medium, having a sensor unit with a wall in contact with the medium, and at least one pH-sensitive material, which has at least one spin state that changes as a function of a pH value. The at least one pH-sensitive material is arranged in or on a region of the wall in such a way that the at least one spin state is subjected to a change in the pH value of the medium. The pH-sensor also includes a spin-sensitive unit, which is configured to detect a variable associated with the at least one spin state, wherein the spin-sensitive unit is arranged in an environment of the at least one pH-sensitive material such that the spin-sensitive unit is subjected to a change in the spin state of the at least one pH-sensitive material.

Nitrogen vacancy (NV) centers in diamond combine exceptional sensitivity with nanoscale spatial resolution by optically detected magnetic resonance (ODMR). Infrared (IR)-absorption-based readout of the NV singlet state transition can increase ODMR contrast and collection efficiency. Here, a resonant diamond metallodielectric metasurface amplifies IR absorption by concentrating the optical field near the diamond surface. This plasmonic quantum sensing metasurface (PQSM) supports plasmonic surface lattice resonances and balances field localization and sensing volume to optimize spin readout sensitivity. Combined electromagnetic and rate-equation modeling suggests a near-spin-projection-noise-limited sensitivity below 1 nT Hz.sup.−1/2 per μm.sup.2 of sensing area using numbers for contemporary NV diamond samples and fabrication techniques. The PQSM enables microscopic ODMR sensing with IR readout near the spin-projection-noise-limited sensitivity, making it appealing for imaging through scattering tissues and spatially resolved chemical NMR detection.

A microscope objective is disclosed comprising; a lens; a housing; a lens holder that is arranged to couple the lens to the housing; a first conductor and a second conductor, the first conductor and the second conductor extending along a sidewall of the housing, the first conductor and the second conductor being arranged to form at least one loop that is that is disposed about at least a portion of a perimeter of a field of view of the lens.

An object provide a technique capable of measuring temperature on the basis of optically detected magnetic resonance with higher precision, The object is achieved by a method for measuring the temperature of an object on the basis of optically detected magnetic resonance of an inorganic fluorescent particle, including (a) irradiating the object, containing the inorganic fluorescent particle with each of multiple microwaves having different frequencies, (b) measuring the fluorescence intensities of the inorganic fluorescent particle with individual photon counters at the time of irradiation of respective microwaves, (c) correcting the fluorescence intensities on the basis of dependencies in the number of pulse measurements between the photon counters and (d) Calculating the temperature of the object on the basis of the obtained fluorescence intensity with the correction values.

The present application discloses a sensor system that includes a sensor having a sensor surface, a sample cartridge including one or more flexible membranes and a membrane frame, the membrane frame including one or more openings covered by the one or more flexible membranes defining one or more wells for holding one or more samples, the flexible membrane having a sample side supporting the sample and an opposite sensor side, the sample cartridge being removably insertable in the sensor system such that the sensor side of the flexible membrane is positioned above and faces the sensor surface, a displacement mechanism that can be actuated to displace the flexible membrane toward the sensor surface such that the sample is moved to a position closer to the sensor surface, and an optical imaging system that detects light emitted from the sensor. Disclosed also are a cartridge cassette and a method of use.

In a measurement using a quantum sensor, the range of measurable physical quantities is increased while maintaining sensor sensitivity. A measuring device (10) comprises an irradiation unit (2) that irradiates a quantum sensor element (1) with electromagnetic waves for operating an electron spin state of the quantum sensor element (1) that changes due to interaction (8) with a measurement target (9), in a pulse sequence in which a time τ between n/2 pulses is a variable value; and a physical quantity measuring unit (3) that calculates a physical quantity of the measurement target based on the electron spin state after the interaction with the measurement target (9).

A measurement apparatus that includes a static magnetic field application part that applies a static magnetic field in a first direction to a measurement subject, a deflection magnetic field application part that applies a deflection magnetic field in a second direction different, to a portion of the measurement subject via a coil, a plurality of magnetic field detection elements respectively detect a magnitude of a magnetic field on the basis of an electromagnetic wave generated and propagated in a portion of the measurement subject due to an application of the deflection magnetic field, a calculation part that calculates an impedance distribution of at least a portion of a region where the electromagnetic wave is propagated inside the measurement subject, and an image information output part that generates and outputs an image showing information about inside the measurement subject.