A variety of application can use nuclear magnetic resonance as an investigative tool. Nuclear magnetic resonance measurements can be conducted using a nuclear magnetic resonance microscope. An example nuclear magnetic resonance microscope can comprise a film embedded in a coverslip, where the film is doped with reactive centers that undergo stable fluorescence when illuminated by electromagnetic radiation having a wavelength within a range of wavelengths and a magnetic field generator to provide a magnetic field for nuclear magnetic resonance measurement of analytes when disposed proximal to the film. Microwave striplines on the coverslip can be arranged to generate microwave fields to irradiate the analytes for the nuclear magnetic resonance measurement. Control of the microwave signals on the microwave striplines can be used for dynamic nuclear polarization in the nuclear magnetic resonance measurement of analytes.

An apparatus for measuring a magnetic field strength is provided. The apparatus includes a stage on which a sample to be measured is placed, a cantilever having a tip, an optical system having a light source and a light receiver, and a microwave power source. The tip is a diamond tip having a nitrogen vacancy defect. The optical system is configured such that excitation light from the light source is focused at the diamond tip. The cantilever is configured as a coaxial microwave antenna through which microwaves from the microwave power source are supplied to the diamond tip.

MR device (100) comprising a miniaturized magnetic resonance system (101) and a cell culture chamber (502) for the analysis of biological samples of less than about 1000 μm in size, wherein said device (100) is at least partially covered by a passivation-binding layer (800). The invention also concerns a method for manufacturing said device (100), comprising a step of depositing a thin passivation-binding layer (800) on said system (101) The depositing step is preferably performed through a deposition process selected from chemical vapor deposition and physical vapor deposition.

Disclosed is a multi-channel atomic magnetic detector (100), including at least one detection assembly, with each detection assembly including a plurality of detection air chambers (130) in the same plane and a light-splitting member (110) for allocating polarized beams from a light source (180) to each detection air chamber (130) in the detection assembly, wherein the plurality of detection air chambers (130) of each detection assembly are arranged in a centrally symmetric manner or an axially symmetric manner relative to the light-splitting member (110). The multi-channel atomic magnetic detector (100) has a high detection density and is beneficial for noise reduction.

A diamond magnetic sensor including diamond containing at least one NV.sup.− center, a microwave generator which emits microwaves to the diamond, an excitation light generator which emits excitation light to the NV.sup.− center of the diamond, and a fluorescence sensor which receives fluorescence produced from the NV.sup.− center of the diamond includes a pattern measurement apparatus which measures a temporal change pattern of magnetic field intensity based on variation in fluorescence intensity sensed by the fluorescence sensor.

A method for generating a nuclear magnetic resonance spectrum of nuclear spin moments of a sample includes a static magnetic field permeating the sample, and a detection spin moment with a detection region surrounding the latter. The detection region extends at least partly into the sample. The method also includes an antenna element for radiating in frequency pulses for influencing the nuclear spin moments and radio-frequency pulses for influencing the detection spin moment, where a polarization step involves polarizing at least one portion of the nuclear spin moments along the magnetic field to form a longitudinal magnetization, where a transfer step involves converting the longitudinal magnetization (M.sub.x) into a transverse magnetization (M.sub.xy) by radiating in a frequency pulse (F) with a 90° flip angle, wherein a detection step involves radiating in a sequence of radio-frequency pulses onto the detection spin moment and subsequently detecting a signal (32′) of the transverse magnetization (M.sub.xy) present in the detection region and storing the signal as detection result in a list. The detection step is carried out a number of times repeatedly in succession, wherein the polarization step and the transfer step and also the detection steps are carried out.

A measurement device includes a microwave generator, an electron spin resonance member, and an observation system. The microwave generator is configured to generate a microwave. The microwave is configured for an electron spin quantum operation based on a Rabi oscillation. The microwave generator has a coil configured to emit the microwave and an electrostatic capacitance member electrically connected in parallel to the coil. The microwave is irradiated to the electron spin resonance member. The observation system is configured to measure a physical quantity in a measured field in response to a state of the electron spin resonance member when the electron spin resonance member is irradiated by the microwave. The electrostatic capacitance member is directly connected to the coil or is arranged between the coil and an electric element that is electrically connected to the coil.

The vectorial magnetometer and associated methods can allow to distinguish the relative superposed amplitudes associated to different spin populations based on the known proportions of the Rabi attenuation in the different characteristic orientations of the spin populations due to application of different pulse parameters which can be specifically selected to create a contrast between the attenuation proportions stemming from the different spin populations.

A magnetometer includes a sample signal device; a reference signal device; a microwave field generator operable to apply a microwave field to the sample signal device and the reference signal device; an optical source configured to emit light including light of a first wavelength that interacts optically with the sample signal device and with the reference signal device; at least one photodetector arranged to detect a sample photoluminescence signal including light of a second wavelength emitted from the sample signal device and a reference photoluminescence signal including light of the second wavelength emitted from the reference signal device, in which the first wavelength is different from the second wavelength; and a magnet arranged adjacent to the sample signal device and the reference signal device.

Polarized nuclear imaging and spectroscopy systems and methods are disclosed. In some embodiments, nuclei of a radioactive substance are polarized such that the spins of the nuclei are oriented in a specific direction, to generate a polarized radioactive tracer with anisotropic gamma ray emission. The radioactive substance is selected such that the degree of anisotropy is enhanced. A tracer is introduced into a living subject for delivery to a target area of interest in the subject. The tracer is delivered such that nuclear spin relaxation of the tracer is inhibited during transport of the tracer to the target area of interest. Gamma rays from the gamma ray emission are detected, and based on the detected gamma rays and properties associated with the anisotropic gamma ray emission, imaging data and/or spectroscopic data are obtained that are associated with the tracer in the subject. In some embodiments, a radioactive substance is delivered to a target area of interest in the subject and the nuclei of the radioactive substance are polarized following delivery of the radioactive substance to the target area of interest, such that the spins of the nuclei are oriented in a specific direction, to generate a polarized radioactive tracer with anisotropic gamma ray emission. Gamma rays are detected from the gamma ray emission, and based on the detected gamma rays and properties associated with the anisotropic gamma ray emission, imaging data and/or spectroscopic data are obtained that are associated with the tracer in the subject.