Methods and apparatus for determining at least one metabolic state of a subject using a nuclear magnetic resonance (NMR) monitoring device. The NMR monitoring device comprises at least one magnet configured to generate a primary magnetic field, a transceiver coil arranged within the primary magnetic field, wherein the transceiver coil is configured to apply a time series of radiofrequency (RF) pulses to a portion of a subject located within the primary magnetic field and detect an NMR signal generated in response to application of the time series of RF pulses, and an NMR spectrometer communicatively coupled to the transceiver coil. The NMR spectrometer is configured to process the detected NMR signal to determine at least one metabolic state of the subject.

A probe unit (100) including a magnet (102, 103) generates a static magnetic B.sub.0 field in an examination region and a RF coil (105). An input-output module (201) includes a transmitter (203) which controls the RF coil (105) to excite resonance and cause echoes (210) and a receiver (204) which demodulates and digitizes the echoes (210). A data processing module (206) includes at least one processor programmed to calculate a T.sub.2 relaxation distribution plot from a digitized echo (210) train, calculate a first area under the fat peak on the T.sub.2 distribution plot, calculate a second area under a water peak on the T.sub.2 distribution plot, and normalize the first and second area to determine a fat-to-water ratio.

This disclosure relates to medical fluid sensors and related systems and methods. In certain aspects, a nuclear magnetic resonance device includes a support frame, a first magnet connected to the support frame, a second magnet connected to the support frame in a manner such that the second magnet is disposed within the magnetic field of the first magnet and a magnetic attraction exists between the first magnet and the second magnet, and a spacer disposed between the first magnet and the second magnet. The spacer is configured to maintain a space between the first magnet and the second magnet.

This disclosure relates to medical fluid sensors and related systems and methods. In certain aspects, a nuclear magnetic resonance device includes a support frame, a first magnet connected to the support frame, a second magnet connected to the support frame in a manner such that the second magnet is disposed within the magnetic field of the first magnet and a magnetic attraction exists between the first magnet and the second magnet, and a spacer disposed between the first magnet and the second magnet. The spacer is configured to maintain a space between the first magnet and the second magnet.

A nuclear magnetic resonance (NMR) apparatus includes at least one magnet configured to induce a static magnetic field in a sample of material to be analyzed. At least one radio frequency antenna is configured to induce a radio frequency magnetic field in the sample of material to be analyzed. The sample chamber is disposed in a substantially longitudinally continuous sample holder separated into discrete sample chambers. Each sample chamber has an internal opening dimension such that substantially all of each sample is affected by surface contact phenomena with an internal wall of each sample chamber.

A nuclear magnetic resonance (NMR) apparatus includes at least one magnet configured to induce a static magnetic field in a sample of material to be analyzed. At least one radio frequency antenna is configured to induce a radio frequency magnetic field in the sample of material to be analyzed. The sample chamber is disposed in a substantially longitudinally continuous sample holder separated into discrete sample chambers. Each sample chamber has an internal opening dimension such that substantially all of each sample is affected by surface contact phenomena with an internal wall of each sample chamber.

Apparatuses and methods are provided for concentrating the magnetization of nuclear spins within a body, in one apparatus, a body having an electron spin moments and nuclear spin moments may subject to a polarizing magnetic field and a gradient magnetic field, such that a space-varied distribution of magnetic resonant frequencies of respective electron spin moments in the body is induced. The body may then be subject to a time-varying magnetic field configured to induce a spatial gradient of the electron spin magnetization such that concentrations of nuclear spin magnetization are induced. The body may be configured to receive a biological sample such that a concentration of nuclear spin magnetization may diffuse into the biological sample. The apparatus may further include a sensor configured to detect nuclear spin magnetization within the biological sample.

Apparatuses and methods are provided for concentrating the magnetization of nuclear spins within a body, in one apparatus, a body having an electron spin moments and nuclear spin moments may subject to a polarizing magnetic field and a gradient magnetic field, such that a space-varied distribution of magnetic resonant frequencies of respective electron spin moments in the body is induced. The body may then be subject to a time-varying magnetic field configured to induce a spatial gradient of the electron spin magnetization such that concentrations of nuclear spin magnetization are induced. The body may be configured to receive a biological sample such that a concentration of nuclear spin magnetization may diffuse into the biological sample. The apparatus may further include a sensor configured to detect nuclear spin magnetization within the biological sample.

According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B.sub.0 coil configured to contribute to a B.sub.0 field suitable for use in low-field magnetic resonance imaging (MRI).

According to some aspects, a laminate panel is provided. The laminate panel comprises at least one laminate layer including at least one non-conductive layer and at least one conductive layer patterned to form at least a portion of a B.sub.0 coil configured to contribute to a B.sub.0 field suitable for use in low-field magnetic resonance imaging (MRI).