A method of determining components present in a sample from spectral data obtained from the sample including resolving each of a plurality of models of the spectral data, the plurality of models including models having a different number of component reference spectra selected from a set of predetermined component reference spectra; selecting a one of the plurality of models based upon a model selection criterion and determining one or more components present in the sample based upon the selected model. The model selection criterion includes a measure for each model, which balances improvements in fit quality of the model to the spectral data against a complexity penalty determined from the number of component reference spectrum used in the model.

A method for automatically quantifying an analyte in a measurement sample includes providing a 1D-NMR spectrum and a 2D-NMR spectrum, providing at least one information item in relation to at least one analyte to be quantified, establishing a chemical shift of the NMR signal of the analyte to be quantified from the measured 2D-NMR spectrum using the at least one information item provided, establishing expected peak positions of the NMR signal of the analyte to be quantified, establishing measured peak positions from the measured 1D-NMR spectrum, and establishing disturbance signal peak positions using the expected peak positions and the actual peak positions. The method further includes modelling the 1D-NMR spectrum using the established disturbance signal peak positions using the established chemical shift and using the at least one information item provided, integrating the modelled 1D-NMR spectrum, and quantifying the analyte by internal or external referencing.

An information processing apparatus includes information acquisition means configured to acquire quantitative information on a test substance, which is estimated by inputting spectrum information of a sample including the test substance into a learning model, and degree-of-contribution acquisition means configured to acquire a degree of contribution of the acquired quantitative information on the test substance.

An NMR magnet system uses a Stirling cooler having a cold head that extends into a housing of the system to cool a cold shield surrounding a cryogen vessel. The system may have a damper located between the cooler and the cold shield to reduce a transmission of vibration from the cooler to a magnet coil immersed in the cryogen. The damper may be passive, or may be part of an active damping system that uses an acceleration sensor to drive an active damper that compensates for cooler vibration. A compensation apparatus may use a stored characteristic of a signal distortion caused by the vibration and, in response to a trigger signal from the cooler, apply compensation to an excitation signal provided to a sample by an NMR probe in a bore of the magnet coil, or to an FID signal from the sample that is detected by the probe.

A system for measuring electromagnetic radiation, comprising at least one light source; a quantum converter arranged to be exposed to radiation emitted by the at least one light source and the electromagnetic radiation, and at least one detector for detecting optical radiation received from the quantum converter. The quantum converter comprises at least a first interaction zone and a second interaction zone, and the system establishes at least a first light beam path for exposing the first interaction zone and a second light beam path for exposing the second interaction zone with radiation emitted by the at least one light source. Each laser beam path is controllable to be in an activated state enabling exposure and in a deactivated state preventing exposure of the respective interaction zone.

A system and method for determining a nuclear magnetic resonance relaxation time of a probe includes polarizing first nuclei and second nuclei by applying a longitudinal static magnetic field to the probe, exchanging the polarizations of the first nuclei and the second nuclei by irradiating a swap sequence of transverse magnetic field pulses, transversely magnetizing the second nuclei by irradiating at least one excitation pulse and measuring the resulting magnetization signal of the second nuclei, and determining the nuclear magnetic resonance relaxation time of the second nuclei based on the measured magnetization signal of the second nuclei.

The present application describes techniques for determining and eliminating a time delay between a radio frequency pulse and a layer selection gradient in a magnetic resonance device. The techniques for determining and eliminating the time delay direct include measuring the time delay between the layer selection gradient and the radio frequency pulse by using phase information. This technique is more sensitive and accurate than existing methods that use signal or artifact strength.

Systems and methods for determining proton spectral characteristics associated with a pair of targets from an MRI data volume are provided. The methods can include identifying spectral widths and peak-to-peak distance associated with the targets from the MRI data volume. The targets could include water and fat. The identified proton spectral characteristics can be useful for accurate spectral fat saturation, improving dynamic shim routines, and optimizing bandwidth of radiofrequency pulses used in multi-slice or multi-band excitation.

An MR signal processing apparatus according to one embodiment includes processing circuitry. The processing circuitry inputs a plurality of MRS signals acquired by MR spectroscopy on the same target to a trained model, and outputs a parameter for MRS reconstruction.

Embodiments of a compact portable nuclear magnetic resonance (NMR) device are described which generally include a housing that provides a magnetic shield; an axisymmetric permanent magnet assembly in the housing and having a bore, a plurality of magnetic elements that together provide a well confined axisymmetric magnetization for generating a near-homogenous magnetic dipole field B.sub.0 directed along a longitudinal axis and providing a sample cavity for receiving a sample, and high magnetic permeability soft steel poles to improve field uniformity: a shimming assembly with coils disposed at the longitudinal axis for spatially correcting the near homogenous magnetic field B.sub.0; and a spectrometer having a control unit for measuring a metabolite in the sample by applying magnetic stimulus pulses to the sample, measuring free induction delay signals generated by an ensemble of hydrogen protons within the sample; and suppressing a water signal by using a dephasing gradient with frequency selective suppression.