The present application provides a magnetic resonance imaging scan method, a magnetic resonance imaging system, and a non-transitory computer-readable storage medium. The magnetic resonance imaging scan method comprises indicating in real time values of parameters associated with an implant device in a tested object and safety status of one or a plurality of the parameters during performing an imaging scan.

The present disclosure provides a method that includes applying at least one radiofrequency saturation pulse at a frequency or a range of frequencies to substantially saturate magnetization corresponding to an exchangeable proton in the ROI to generate magnetic resonance (MR) data. The MR data is then acquired using an echo-planar imaging readout, which is configured to sample a series of gradient echo pulse trains at a series of gradient echo times and a series of spin echo pulse trains at a series of spin echo times. One or more relaxometry measurement is then computed using the MR data sampled at the gradient echo times and the spin echo times. An oxygen-weighted image is then generated using the one or more relaxometry measurement, and a pH-weighted image is generated using MR data sampled at one or more of the spin echo times or gradient echo times.

Described herein are systems, methods, and computer-readable medium for magnetic resonance (MR) based thermometry. In one aspect, in accordance with one embodiment, a method for magnetic resonance based thermometry includes: acquiring, by a variable flip-angle T1 mapping sequence, MR data in an area of interest of a subject that is heated by the application of focused ultrasound (FUS) to the brain of the subject, where the MR data includes T1 values over time, and where the acquisition of the MR data includes applying an accelerated three-dimensional ultra-short spiral acquisition sequence with a nonselective excitation pulse; and determining, based at least in part on a mathematical relationship established by T1 mapping thermometry, a temperature change in the area of interest over time, and where the temperature change is caused at least in part by a change in the applied FUS.

The present disclosure provides a system for MRI. The system may obtain a plurality of echo signals relating to a subject that are excited by an MRI pulse sequence applied to the subject. The system may perform a quantitative measurement on the subject based on the plurality of echo signals. The MRI pulse sequence may include a CEST module configured to selectively excite exchangeable protons or exchangeable molecules in the subject, an RF excitation pulse applied after the CEST module configured to excite a plurality of gradient echoes, and one or more refocusing pulses applied after the RF excitation pulse. Each of the refocusing pulses may be configured to excite one or more spin echoes. The one or more spin echoes excited by at least one of the one or more refocusing pulses may include a symmetric spin echo and one or more asymmetric spin echoes.

In a method for filtering magnetic resonance (MR) image data, complex MR image data is acquired from a region to be imaged, and a sliding window averaging is applied to the complex MR image data to generate filtered MR image data. For each window position of the sliding window averaging: a phase variation of the complex MR image data of individual image points of a sliding window is estimated with a model using a linear phase progression, and filtered complex MR image data is generated based on the estimated phase variation of the complex MR image data. The generation of the filtered complex MR image data uses an average formation of the complex MR image data of the individual image points of the sliding window.

A pH-weighted chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method and system are provided that works by indirectly measuring the NMR signal from amine protons found on the backbones of amino acids and other metabolites, which resonate at a frequency of +2.8-3.2 ppm with respect to bulk water protons. The technique uses a modified magnetization transfer radiofrequency saturation pulse for the generation of image contrast. A train of three 100 ms Gaussian pulses at high amplitude (6 uT) or Sinc3 pulses are played at a particular frequency off-resonance from bulk water prior to a fast echo planar imaging (EPI) readout, with one full image acquired at each offset frequency. This non-invasive pH-weighted MRI technique does not require exogenous contrast agents and can be used in preclinical investigations and clinical monitoring in patients with malignant glioma, stroke, and other ailments.

The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering a new dual-frequency dynamic nuclear polarization (DNP) method that uses a microwave beam to polarize the spins of electrons and concomitantly act as a NMR transmitter.

The disclosure relates to a method for correcting image data acquired by a magnetic resonance device, a magnetic resonance device, and a computer program product. According to the method, first navigator data, image data, and second navigator data are acquired. Moreover, temperature values of the magnetic resonance device are determined. The image data is corrected based on the first navigator data, the second navigator data, and the temperature values.

The present invention relates to on the use of exogenous agents having a pool of mobile proton(s) in CEST-MR imaging to generate Chemical Exchange Rotation Transfer/based CEST contrast, and to a ratiometric-based CEST-MR procedure that comprises using these exogenous agents to set-up CERT-based concentration-independent CEST MR imaging, and as responsive agents to set-up CERT-based concentration independent responsiveness.

A pH-weighted chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method and system are provided that works by indirectly measuring the NMR signal from amine protons found on the backbones of amino acids and other metabolites, which resonate at a frequency of +2.8-3.2 ppm with respect to bulk water protons. The technique uses a modified magnetization transfer radiofrequency saturation pulse for the generation of image contrast. A train of three 100 ms Gaussian pulses at high amplitude (6 uT) or Sinc3 pulses are played at a particular frequency off-resonance from bulk water prior to a fast echo planar imaging (EPI) readout, with one full image acquired at each offset frequency. This non-invasive pH-weighted MRI technique does not require exogenous contrast agents and can be used in preclinical investigations and clinical monitoring in patients with malignant glioma, stroke, and other ailments.