In vivo methods for non-invasively imaging (or measuring without spatial localization) of neuro-electro-magnetic oscillations are achieved by a pulse sequence of radio frequency (RF) irradiation and magnetic field gradients. These RF and gradient pulses create an intermolecular zero-quantum coherence (iZQC), the frequency of which is: 1) controlled by one or more magnetic field gradients; and 2) made to match the frequency of the targeted neuro-electro-magnetic oscillation.

An apparatus to jointly measure oxygen utilization and tissue strain includes an imaging system and a computer processor operatively coupled to the imaging system. The computer processor is configured to control the imaging system to perform a pulse sequence on tissue of a subject. The computer processor also acquires oxygen utilization data and strain data responsive to the pulse sequence. The computer processor further determines an amount of strain on the tissue of the subject based at least in part on the strain data and an amount of oxygen utilization of the tissue of the subject based at least in part on the oxygen utilization data.

In a method (100 to 208) in which hyperpolarizable tracer molecules (20, 88 to 98) are hydrogenated and then optionally also hyperpolarized for magnetic resonance imaging, it is provided that, in a first method step (104, 202), a hydrogen solution (10, 12, 4) having a saturation factor of at least 50% be prepared and that the hydrogenation reaction (186 to 190, 206) not be triggered until a subsequent, second method step (106, 204). An apparatus (1) with which the method of the invention (100 to 208) is executable is also provided.

In a method (100 to 208) in which hyperpolarizable tracer molecules (20, 88 to 98) are hydrogenated and then optionally also hyperpolarized for magnetic resonance imaging, it is provided that, in a first method step (104, 202), a hydrogen solution (10, 12, 4) having a saturation factor of at least 50% be prepared and that the hydrogenation reaction (186 to 190, 206) not be triggered until a subsequent, second method step (106, 204). An apparatus (1) with which the method of the invention (100 to 208) is executable is also provided.

The invention provides a multi-slice magnetic resonance imaging method and device based on long-distance attention model reconstruction. The method includes that: a deep learning reconstruction model is constructed; data preprocessing is performed on multiple slices of simultaneously acquired signals, and multiple slices of magnetic resonance images or K-space data is used as data input; learnable positional embedding and imaging parameter embedding are acquired; the preprocessed input data, the positional embedding and the imaging parameter embedding are input into the deep learning reconstruction model; and the deep learning reconstruction model outputs a result of the magnetic resonance reconstruction image. The invention further provides a device for implementing the method. The invention may improve the quality of the magnetic resonance image, improve the diagnosis accuracy of a doctor, increase the imaging speed, and improve the utilization rate of a magnetic resonance machine.

In a method for actuating a magnetic resonance system including a radio-frequency unit configured to generate a radio-frequency (RF) pulse for saturating nuclear spins in an examination area of an examination object, a BO card of the magnetic resonance system is loaded, frequency information of nuclear spins to be saturated in the examination area is loaded, a subarea of the examination area in which nuclear spins are to be saturated is determined, at least one RF saturation pulse for saturating the nuclear spins to be saturated in the determined subarea is determined based on the BO card and the frequency information, and the RF saturation pulse is output via the radio-frequency unit of the magnetic resonance system.

In a method for determining imaging parameters for a Magnetic Resonance (MR) image, a set of image sequence parameters of the imaging sequence is determined, a frequency offset of off-resonant tissue potentially present in the object under examination is determined, an allowed maximum position shift of the off-resonant tissue along a slice selection direction is determined, a rotation angle which leads to the allowed maximum shift for the off-resonant tissue is determined based on the determined set of image sequence parameters, and the determined rotation angle is provided to the MR imaging system to allow the MR imaging system to generate the MR image using the determined rotation angle in the imaging sequence.

The devices, systems, and methods can improve magnetic resonance imaging (MRI), MR spectroscopy (MRS), MR spectroscopic imaging (MRSI) measurement(s), thereby providing more reliable quantification. The method may include a method for correcting MR image(s)/spectrum. The method may include providing an inhomogeneity field/response map of a region of interest; and providing MR image(s)/spectrum of the region of interest. The method may include determining an intravoxel/voxel inhomogeneity correction coefficient for each voxel of at least one subregion of the region of the interest using the inhomogeneity field/response map. The method may include correcting each voxel of the MR image(s)/spectrum of the region of interest using the intravoxel/voxel inhomogeneity correction coefficient. The MR image(s)/spectrum may include chemical exchange saturation transfer (CEST)/magnetization transfer (MT) imaging with Z-spectrum, CEST/MT imaging without Z-spectrum, CEST spectroscopy, CEST MRS, MRS, MRSI, or any combination thereof.

The devices, systems, and methods can improve magnetic resonance imaging (MRI), MR spectroscopy (MRS), MR spectroscopic imaging (MRSI) measurement(s), thereby providing more reliable quantification. The method may include a method for correcting MR image(s)/spectrum. The method may include providing an inhomogeneity field/response map of a region of interest; and providing MR image(s)/spectrum of the region of interest. The method may include determining an intravoxel/voxel inhomogeneity correction coefficient for each voxel of at least one subregion of the region of the interest using the inhomogeneity field/response map. The method may include correcting each voxel of the MR image(s)/spectrum of the region of interest using the intravoxel/voxel inhomogeneity correction coefficient. The MR image(s)/spectrum may include chemical exchange saturation transfer (CEST)/magnetization transfer (MT) imaging with Z-spectrum, CEST/MT imaging without Z-spectrum, CEST spectroscopy, CEST MRS, MRS, MRSI, or any combination thereof.

The disclosure facilitates determining patient motion during a magnetic resonance protocol. According to some examples, the patient motion may be corrected or compensated.