An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to receive an input of first ultrasound data and to output second ultrasound data. The processing circuitry is configured to reconstruct third ultrasound data on the basis of amplitude information in the second ultrasound data and phase information in the first ultrasound data. The processing circuitry is configured to perform a process that uses amplitude information and phase information in the third ultrasound data.

Systems and methods for high spatial and temporal resolution ultrasound imaging of microvessels in a subject are described. Ultrasound data are acquired from a region-of-interest in a subject who has been administered a microbubble contrast agent. The ultrasound data are acquired while the microbubbles are moving through, or otherwise present in, the region-of-interest. The region-of-interest may include, for instance, microvessels or other microvasculature in the subject. By imaging microbubbles, a cross-correlation map between each microbubble image and a point spread function of the system can be generated. Accumulation of power-based cross-correlation maps may then be used to generate a high-resolution high-contrast image of the microvasculature.

Circuitry for ultrasound devices is described. A multilevel pulser is described, which can provide bipolar pulses of multiple levels. The multilevel pulser includes a pulsing circuit and pulser and feedback circuit. Symmetric switches are also described. The symmetric switches can be positioned as inputs to ultrasound receiving circuitry to block signals from the receiving circuitry.

The present invention relates to an apparatus (10) for tracking a position of an interventional device (11) respective an image plane (12) of an ultrasound field. The position includes an out-of-plane distance (Dop). A geometry-providing unit (GPU) includes a plurality of transducer-to-distal-end lengths (Ltde.sub.1 . . . n), each length corresponding to a predetermined distance (Ltde) between a distal end (17, 47) of an interventional device (11, 41) and an ultrasound detector (16, 46) attached to the interventional device, for each of a plurality of interventional device types (T.sub.1 . . . N). An image fusion unit (IFU) receives data indicative of the type (T) of the interventional device being tracked; and based on the type (T): selects from the geometry-providing unit (GPU), a corresponding transducer-to-distal-end length (Ltde); and indicates in a reconstructed ultrasound image (RUI) both the out-of-plane distance (Dop) and the transducer-to-distal-end length (Ltde) for the interventional device within the ultrasound field.

Circuitry for ultrasound devices is described. A multilevel pulser is described, which can provide bipolar pulses of multiple levels. The multilevel pulser includes a pulsing circuit and pulser and feedback circuit. Symmetric switches are also described. The symmetric switches can be positioned as inputs to ultrasound receiving circuitry to block signals from the receiving circuitry.

A Doppler measurement system includes a random generator outputting a control signal encoding a random selection, and an ultrasonic array transducer for emitting a sequence of transmit pulses at a target at either an adjustable steering angle (plane wave imaging) or from a selectable non-sequential transducer element order (synthetic aperture imaging) corresponding to the random selection and for receiving an echo of each transmit pulse reflected from the target. Each transmit pulse is independently adjusted to a steering angle (plane wave imaging) or selectable transducer element order (synthetic aperture imaging) corresponding to a unique random selection so that the sequence of transmit pulses is a random sweep. The system can also include a memory for storing echo data, and a processor connected to the memory for using transmit data and echo data to extract a Doppler parameter. Methods of Doppler measurement and computer-readable medium can incorporating the measurement system.

This two-dimensional Fourier transform ultrasound imaging method includes by controlling transmitting and receiving transducers: obtaining M matrices MR.sub.m, 1≤m≤M, of sampled ultrasonic time signals; two-dimensional Fourier transforming each matrix MR.sub.m to obtain M spectral matrices FTMR.sub.m; converting each spectral matrix FTMR.sub.m to obtain M spectral images FTI.sub.m; combining the M spectral images FTI.sub.m and two-dimensional inverse Fourier transforming the resulting spectral image FTI to obtain an ultrasound image I. The conversion includes taking into account a change of propagation mode during a backscatter, by adding a parameter characterizing this change of mode in equations (SYS) of change of reference frame, and/or taking into account a reflection against a wall, by adding a phase shift term in a relation (REL) of matrix transformation.

Method for ultrasonic characterization of a medium, including generating a series of incident ultrasonic waves, generating an experimental reflection matrix R.sub.ui(t) defined between the emission basis (i) as input and a reception basis (u) as output, and determining a focused reflection matrix RFoc(r.sub.in, r.sub.out, δt) of the medium between an input virtual transducer (TV.sub.in) calculated based on a focusing as input to the experimental reflection matrix and an output virtual transducer (TV.sub.out) calculated based on a focusing as output from the experimental reflection matrix, the responses of the output virtual transducer (TV.sub.out) being obtained at a time instant that is shifted by an additional delay Ot relative to a time instant of the responses of the input virtual transducer (TV.sub.in).

Described herein are methods and apparatus for increasing sensitivity of ultrasound imaging of fluid flow in an object of interest. Ultrasound imaging of blood perfusion can be performed without contrast enhancement. Embodiments include transforming a spatiotemporal echo data array into a three-dimensional perfusion data array having a spatial dimension, a slow-time dimension, and a frame-time dimension, and filtering the perfusion data array with an eigen passband clutter filter. The clutter filter can increase sensitivity and utility of ultrasound imaging of fluid flow. In some aspects, the method can yield blood flow signal power and perfusion values well separated from tissue clutter. In an example, enhancements to ischemic tissue perfusion maps in a murine model are shown.

This disclosure describes systems and methods for crosstalk-free source encoding for ultrasound tomography. This disclosed systems and methods feature real data acquisition acceleration and/or numerical simulation acceleration (or image processing acceleration).