Disclosed herein are nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a HBV and/or HDV and/or HIV infection with one or more nucleotide analogs.

An article including a front region, a back region, and a chassis. The chassis may include an absorbent core having a front end edge and a back end edge. The front region and the back region may extend laterally outward beyond side edges of the chassis. The front region and the back region may abut to form a first seam and a second seam. At least one of the front region and the back region may include an elastic member. A first outer nonwoven layer of the front region and a second outer nonwoven layer of the back region may be folded to form an upper edge in the front and back regions such that a distal end of each of the first and second outer nonwoven layer may be disposed between the upper edge and the front and back end edges of the absorbent core, respectively.

A sensor system for detecting a property of or within an absorbent article may comprise an absorbent article and an auxiliary article.

A sensor system for detecting a property of or within an absorbent article may comprise an absorbent article and an auxiliary article.

A patterned apertured web is disclosed. The patterned apertured web includes a plurality of land areas in the patterned apertured web and a plurality of apertures defined in the patterned apertured web. At least some land areas of the plurality of land areas surround at least some apertures of the plurality of apertures. The patterned apertured web has an Effective Open Area in the range of about 3% to about 30%, according to the Aperture Test herein. The plurality of apertures include a first set of apertures defining a first shape and a second set of apertures defining a second shape. The first shape is positioned within the second shape.

An absorbent article or an array of absorbent articles comprising visual characteristics.

Absorbent articles comprising a multilayer outer cover comprising a first outer layer and a second outer layer comprising a component that exhibits at least partial elastic recovery after mechanical activation in the machine direction; an inner layer, disposed between the first outer layer and the second outer layer, the inner layer comprising elastic strands; and wherein at least one of the first outer layer and second outer layer is laminated to the inner layer.

A nonwoven fabric. The nonwoven fabric can include a first surface and a second surface and a visually discernible pattern of three-dimensional features on one of the first or second surface. Each of the three-dimensional features can define a microzone comprising a first region and a second region. The first and second regions can have a difference in values for an intensive property. The nonwoven further has a plurality of apertures, wherein at least a portion of the aperture abuts at least one of the first region and the second region of the microzone.

An absorbent article has a liquid pervious topsheet, a liquid impervious backsheet, an absorbent core disposed between the topsheet and backsheet; first and second opposing longitudinal side edges, a front waist region and a back waist region; and a first and second back ear extending outwardly from the first and longitudinal side edges in the back waist region, respectively. The first and second back ears have an engineering strain greater than about 8% at about or below 2N of force when measured according to the Back Ear Extension Test, and a roughness Ra lower than about 300 μm when measured according to the Roughness Test.

A system of pantiliners and menstrual pads that can be used to alleviate undesirable conditions associated with dysmenorrhea or other physiological conditions is provided. The pantiliners of the invention include a top layer of composite material, a ventilation layer, and a bottom layer of breathable material. The menstrual pads of the invention include a top layer of composite material, an air-laid layer, a layer of super adsorbent polymer inside the air-laid layer, a ventilation layer, and a bottom layer of breathable material. The present system of pantiliners and menstrual pads is helpful in providing a decrease of pain and other unwanted symptoms during a menstrual cycle. In another advantage, the right placement guide and the left placement guide are provided to assist in placing the menstrual pads of the invention accurately in relation to the undergarment of the user.