Methods are disclosed for non-invasively obtaining fetal cells from a pregnant female. The methods include placing an absorbent medium in an interlabial or intravaginal space or adjacent to the perineum at the vaginal opening of the pregnant female, and collecting vaginal fluid comprising cells in the absorbent medium while the absorbent medium is interlabial or intravaginal space or adjacent to the perineum at the vaginal opening. The absorbent medium is removed and cells are isolated from the absorbent medium to obtain the fetal cells. The fetal cells can be, for example, somatic cells, embroyic stem cells, fetal stem cells or trophoblast cells.

The present disclosure provides diaper prediction and correction system and method. This system includes a diaper sensor, a server and a mobile device. The server is configured to store crowdsourcing data including a plurality of sensing criteria corresponding to a plurality of geographic regions, different genders, a plurality of ages, a plurality of diaper data. The mobile device is configured to execute a mobile application to pair with the diaper sensor and to transmit a location information, a wearer's sex and age, and a brand or a model of a diaper to the server, so that the server selects a corresponding sensing criterion from the sensing criteria and returns the corresponding sensing criterion to the mobile device, and the mobile device is based on the corresponding sensing criterion to determine whether a diaper sensing signal from the diaper sensor reflect that the diaper needs to be replaced.

The present disclosure concerns a wound monitoring system for monitoring a bacterial 5 infection at a wound site, comprising a biosensing module that is contactable with the wound site, the biosensing module being configured to output a signal indicative of presence of at least one biomolecule released by bacterial cells at the wound site, and a readout circuitry coupled to the biosensing module for wirelessly transmitting the signal to an external device. The signal is a change in dielectric permittivity of the biosensing module. The present disclosure concerns a method of fabricating the wound monitoring system and a method of monitoring a bacterial infection at the wound.

Described herein are apparatus and methods for detecting substances of abuse or other analytes in liquids. For example, the apparatus and methods described herein can be used for real-time detection of analytes, such as substances of abuse. The methods comprise providing a detection area comprising a chromatographic membrane capable of receiving the liquid and allowing for migration of the liquid, the chromatographic membrane comprising an anti-analyte antibody-particle conjugate, an analyte-conjugate protein at a test line; exposing at least the first location of the apparatus to the liquid; and determining whether an interaction between the analyte-conjugate protein and the liquid occurs to detect the presence of the analyte. The chromatographic membrane may further comprise an anti-species antibody at a control line. Specific buffers are disclosed, and these buffers may be used in the preparation of the apparatus to overcome challenges associated with miniaturization and challenges associated with exposure to beverages.

Described herein are a wearable apparatus and methods for detecting the presence of a targeted substance in a liquid. For example, the wearable apparatus can be a fingernail that detects illicit drugs in a beverage. The wearable apparatus comprises a detection layer comprising an indicator that is configured to display a signal upon the detection of an interaction with the targeted substance. In some examples, the wearable apparatus can include a lateral flow assay.

One embodiment of the present invention provides an apparatus for analyzing a liquid comprising a plurality of different substances. The apparatus includes an absorber that comprises one or more layers of absorbent material for absorbing the liquid and one or more sensors embedded within the one or more layers of absorbent material. The sensors are configured to provide information associated with the different substances included in the absorbed liquid, and a location of a respective sensor is determined based on a corresponding substance detected by the sensor and a diffusion property of the substance.

One embodiment of the present invention provides an apparatus for analyzing substances included in a sample. The apparatus includes a physical enclosure for holding the sample and one or more sensors positioned on an inner surface of the physical enclosure. The sensors are configured to provide information associated with the substances included in the sample. The apparatus further includes electrical conductive traces positioned on the inner surface and coupled to the one or more sensors, thereby facilitating transmission of outputs of the sensors.

A liquid measurement article includes an absorbent wicking layer and a marking cluster having at least one mark whose location on the article is calibrated to correspond to a particular quantity of liquid having been deposited on the article at a liquid receiving site thereof and having wicked toward the mark. A label associated with at least one of the marks indicates the particular quantity.

Disclosed is fluid rapid testing device, comprising: a box body having transparent side walls, a box cover cooperating with an opening of the box body, and a protection cover hinged to the box cover; wherein the testing device further comprises: a fluid sampling swab, a fluid collection chamber operable to accommodate the fluid sampling swab and collect a fluid on the fluid sampling swab, and a fluid collection groove in communication with a bottom of the fluid collection chamber; and a testing strip extending into the fluid collection groove is arranged on at least one inner wall of the box. The testing device according to the present invention has a simple structure and operation convenience. The box body of the testing device may be conveniently and quickly opened or closed, a small amount of fluid is needed, the sampling process is simplified, and the fluid may also be conveniently taken out for subsequently-desired tests.

A lateral flow device for testing a bodily fluid, such as urine, blood, mucous, saliva, etc., is provided. The lateral flow device is configured to be attached to an absorbent article via an attachment mechanism located on the lateral flow device or the absorbent article. The lateral flow device includes a chromatographic medium (e.g., porous membrane) that defines a detection zone that provides a signal indicative of the presence or absence of the analyte. The device may also include a control zone that provides a signal indicative of whether a sufficient amount of bodily fluid has been provided and tested. Regardless of its specific configuration, the lateral flow device is configured to be attached onto the absorbent article to provide a user or caregiver with rapid information about a health condition. For example, the device may be attached onto a diaper to provide information about the presence of enzymes or other compounds often encountered with a patient having a urinary tract infection. This information may provide an early warning system to allow the user or caregiver to seek additional testing and/or treatment. Alternatively, semi-quantitative or quantitative results may be derived from the test.