Prosthesis (1) comprising one porous mesh (2) comprising a first face and a second face opposite the first face, the prosthesis (1) comprising: —one porous strengthening means (6) which strengthens the mesh (2) and is intended to cover at least part of one of said first and second faces of the mesh (2), —fastening means for fastening the strengthening means (3) to the mesh (2), in a position fastened to the mesh (2), the strengthening means (6) covers a peripheral part (7) of one of said first and second faces of the mesh.

A surgical implant (10) comprises an areal, flexible, porous basic structure (12) having a first face and a second face. At least one resorbable dyed film piece (20) is attached to the basic structure (12) and comprises a plurality of solid protrusions emerging from the dyed film piece (20) in a direction away from the basic structure (12). The at least one dyed film piece (20) is arranged in a shape structure which is asymmetric (“E”) in the area of the basic structure (12). Optionally, the implant (10) further comprises an adhesion barrier sheet (16).

An intravascular cell therapy device comprises a scaffold (2, 12) that is radially adjustable between a contracted orientation suitable for transluminal delivery to a vascular locus and an expanded orientation, and a biodegradable matrix provided on at least a portion of the scaffold that is suitable for seeding with cells and degrades in a vascular environment. The scaffold is configured to have a distal piercing tip (5) when in a deployed orientation. The scaffold comprises a plurality of sidewall panels (3, 13, 14) arranged around a longitudinal axis of the scaffold, and adjustable couplings (4) between the panels configured for adjustment between an expanded configuration and a contracted orientation, and in which each sidewall panel comprises a matrix suitable for seeding with cells.

A stent and a stent manufacturing method results in a stent exhibiting improved fracture resistance. The stent has metal portions that shape a tubular outer periphery provided with a gap and a polymer portion that connects the metal portions to each other in the gap. The polymer portion has a curved portion that is curved to be concave toward the outer side from the inner side in the radial direction of the tubular outer periphery.

A vascular filter system comprises a vascular filter (1), a clamp device (50), and a delivery catheter (51). The filter (1) comprises filter elements (6). When used without the clamp device (50), the filter elements (6) move from a closed state to an open state upon elapse of a predetermined period of time. In the closed state the filter elements (6) capture thrombus passing through the inferior vena cava (2). The delivery catheter (51) is employed to deliver the clamp device (50) to the filter (1) after the filter (1) has been deployed in the inferior vena cava (2). The clamp device (50) engages with the filter elements (6) of the filter (1) to clamp the filter (1) in the closed state beyond elapse of the predetermined period of time. Because of the presence of the clamp device (50), the filter elements (6) are no longer free to move from the closed state to the open state upon elapse of the predetermined period of time. In this manner the period of time in which the filter (1) captures thrombus is extended either temporarily or permanently.

A vascular filter system comprises a vascular filter (1), a clamp device (50), and a delivery catheter (51). The filter (1) comprises filter elements (6). When used without the clamp device (50), the filter elements (6) move from a closed state to an open state upon elapse of a predetermined period of time. In the closed state the filter elements (6) capture thrombus passing through the inferior vena cava (2). The delivery catheter (51) is employed to deliver the clamp device (50) to the filter (1) after the filter (1) has been deployed in the inferior vena cava (2). The clamp device (50) engages with the filter elements (6) of the filter (1) to clamp the filter (1) in the closed state beyond elapse of the predetermined period of time. Because of the presence of the clamp device (50), the filter elements (6) are no longer free to move from the closed state to the open state upon elapse of the predetermined period of time. In this manner the period of time in which the filter (1) captures thrombus is extended either temporarily or permanently.

Soft tissue repair grafts are described comprising an anti-adhesion layer, a structural layer, and a localization layer. These layers may be distinct or integrated into one substrate. The term layer is used to distinguish tissue repair graft functionality rather than distinct material layers. The distinct layers of functionality may comprise a single plane of a substance.

The invention relates to medicine, in particular, to gynecology and urology, namely, to for ligature delivery system for axial fixation of pelvic floor structures in pelvic organ prolapse and stress urinary incontinence. Ligature delivery system for axial fixation of pelvic floor structures in pelvic organ prolapse and stress urinary incontinence consisting of the mesh material that is woven from a non-biodegradable and biodegradable monofilament threads, according to the invention so that non-biodegradable threads are arranged along to the implant axis and are not linked with each other. The technical effect is providing the axial support that is physiological for apical structures of pelvic floor and minimizing risks of mesh-associated postsurgical complications.

A novel single plane tissue repair patch is disclosed. The patch has a base member with an opening therethrough, and a closure member associated with the opening. The mesh may be used in open surgical procedures for hernia repairs and other repairs of body wall defects.

The present invention concerns a bio-resorbable prosthesis (1, 1′) for organs with lumens, as blood vessels and the like, comprising at least one bio-absorbable material layer (2), intended to be arranged in contact with said lumen organ when said prosthesis (1, 1′) is implanted, and at least one auxetic material layer (3), arranged in contact with said at least one bio-absorbable material layer (2).

The present invention also concerns a method for the production of a bio-absorbable prosthesis (1, 1′).