Embodiments disclosed herein relate to prosthetics for augmenting or repairing a tissue defect, such as a ventral or incisional hernia. In some embodiments, a repair prosthetic may include a patch body and a first fastener attached to a first portion of the patch body. A coupler may be attached to and extend from a second portion of the patch body, and a second fastener may be attached to the second portion of the patch body via the coupler. The coupler may be retracted relative to the second portion of the patch body or the second fastener to apply tension to the patch body in some embodiments.

A device includes a first end portion, a second end portion, an intermediate portion between the first end portion and the second end portion, and a graft material coupled to at least the intermediate portion. The first end portion has a first end diameter. The second end portion has a second end diameter larger than the first end diameter. The intermediate portion tapers between the first end portion and the second end portion. A method of diverting fluid flow from a first passage to a second passage comprising deploying the device in a third passage between the first passage and the second passage, expanding the first end portion against sidewalls of the first passage, and expanding the second end portion against sidewalls of the second passage.

The present invention relates to a prosthetic fabric comprising an arrangement of yarns defining at least two faces for said fabric, said fabric comprising, on at least one of its faces, one or more barbs that protrude outwards relative to said face, characterized in that said barbs are covered with a coating made of a water-soluble biocompatible material. The invention also relates to a process for obtaining such a fabric and to prostheses obtained from such a fabric.

A method of treating prolapse of a vagina is provided by placing a reinforcing implant inside of the vagina. The method includes inserting a porous sheet of material inside of the vagina through a natural vaginal opening of the patient. The porous sheet of material is an implantable support that is adapted to integrate with tissue inside of the vagina to reinforce and support at least an apical portion of the vagina. The method includes maintaining the apical portion of the vagina in an anatomically natural position by supporting the porous sheet of material inside of the vagina relative to one of a sacrum and a ligament of the patient.

Novel enhanced products and processes for trapping emboli utilize self-expanding skeletons and biodegradable polymer systems, for example stent-like Nitenol® elements and PLGA, to address longstanding issues related to thrombus capture without deleterious impacts on the vasculature or other negative artifacts of the procedure by at least partial post-use dissolution in situ.

A stent able to minimize occurrences of strain and stress concentration in a drug coat layer upon expansive deformation of the stent in a radial direction to avoid the possibility of the drug separating from the stent, includes a stent body and a drug coating layer coated on the outside surface of the stent body so that the thickness of the drug coating layer gradually decreases toward a bent portion of the stent.

Disclosed is a hybrid surgical mesh that is partially absorbable or biodegradable. The hybrid surgical mesh described herein generally comprises a central absorbable or biodegradable portion surrounded on at least its sides by a non-absorbable portion which forms a support structure for supporting a prolapsed region. While the absorbable or biodegradable portion provides support to the prolapsed region immediately following the surgical procedure to correct such prolapse, over time the central absorbable or biodegradable portion dissolves so as to leave only the non-absorbable interrupted hammock-like support structure. Such configuration provides the initial structural support required after the surgical procedure necessary to ensure healing and strengthening of the prolapsed region, while significantly reducing the risk of healing abnormalities or complications resulting in the central portion of the graft.

A method of effecting a tendon repair in a patient comprising providing a suture tape, using the suture tape to connect tendon tissue to bone of the patient such that the suture tape lays flat on the tendon, and permitting ingrowth of the tendon tissue into the suture tape as the absorbable fibers are absorbed into the patient's tissue. The suture tape is a flat braid of elastic, absorbable fibers and high strength fibers, the tape being at least 1 mm wide and 2 cm long, and less than 1 mm high. The suture tape includes at least 4 absorbable fibers and at least 4 high strength fibers. Further, the suture tape is capable of being stretched at least 10% from its shortest length to the length at which it breaks and is capable of withstanding a load of at least 260 Newtons before breaking.

This disclosure describes, inter alia, materials, devices, kits and methods that may be used to treat chronic sinusitis.

A reinforced graft construct for repairing a tendon or ligament formed by inserting a piece of material, such as suture, through the graft lengthwise. The material may be inserted along only a portion of the graft or along the entire graft. The material may be a reinforcement (reinforcing) material such as suture, tape, weave, or mesh passed lengthwise through the graft (for example, along the center of the graft). The ends of the graft may be whipstitched to provide additional fixation when implanted. The material may be bioabsorbable such that it will resorb away after a period of time in the body.