A device for endovascular treatment to ameliorate aneurysm recurrences by deploying a treatment mesh having a plurality of vertically oriented elongated support reinforcement elements that are substantially parallel and oriented upon a plane in communication with the mesh. Upon deployment, the array of distal ends of the support extensions and reinforcements are substantially oriented upon a plane, which plane is in substantially the same orientation as the opening of the aneurysm into which the device was deployed. The treatment mesh may incorporate a coating of hydrogel, optionally impregnated with pharmaceutical compounds.

A method of implanting a prosthetic heart valve includes advancing a delivery catheter toward a native heart valve, wherein the delivery catheter has a distal capsule containing a prosthetic valve in a compressed state. The prosthetic valve includes a self-expandable interior stent and a self-expandable exterior wire mesh surrounding the interior stent. The exterior wire mesh preferably has a lower radial strength than the interior stent for conforming to a surrounding shape of the native valve. The prosthetic valve is expelled from the distal capsule and allowed to expand within the native valve. Capturing elements extending from a ventricular end of the interior stent trap native leaflets between the capturing elements and an outer surface of the wire mesh.

A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

A side-deliverable prosthetic heart valve includes a valve frame defining an aperture that extends along a central axis and a flow control component mounted within the aperture and configured to permit selective blood flow therethrough. The prosthetic heart valve has a compressed configuration for side-delivery to a heart of a patient via a delivery catheter. The prosthetic heart valve is configured to transition to an expanded configuration when released from the delivery catheter for seating in a native annulus. The valve frame includes distal, proximal, and septal anchoring elements, each of which is insertable through the native annulus prior to seating the prosthetic heart valve therein. The septal anchoring element is configured to extend below the annulus and contact ventricular septal tissue to stabilize the prosthetic heart valve in the annulus when the prosthetic heart valve is seated in the annulus.

An anchoring device that can be positioned within a native valve, such as the native mitral valve, to secure a replacement prosthetic valve in place. The anchoring device can comprise a docking station formed of an elastic tube-like member defining a generally coiled shape. The docking station can have an atrial or stabilization turn, a leading or encircling turn, and a central region. In many embodiments, the docking device possess a plurality of cuts on opposing sides of the tube-like member to allow biasing of the member.

Apparatus and methods are described herein for use in the delivery of a prosthetic mitral valve. In some embodiments, an apparatus includes an epicardial pad configured to engage an outside surface of a heart to secure a prosthetic heart valve in position within the heart. The epicardial pad defines a lumen configured to receive therethrough a tether extending from the prosthetic valve. The epicardial pad is movable between a first configuration in which the epicardial pad has a first outer perimeter and is configured to be disposed within a lumen of a delivery sheath and a second configuration in which the epicardial pad has a second outer perimeter greater than the first outer perimeter. The epicardial pad can be disposed against the outside surface of the heart when in the second configuration to secure the prosthetic valve and tether in a desired position within the heart.

The present disclosure is directed to a system and method for containing a penile prosthesis in a neophallus, to stabilize this device in the neophallus and to give the neophallus additional stiffness in erection. The contained penile prosthesis further resembles a glans at the distal end of the neophallus.

A luminal endoprosthesis assembly (1) at least partially delimits a prosthesis lumen (2), for implantation in an anatomical structure (3) that at least partially defines at least one cavity (4) and includes at least one pathological portion (13). The luminal endoprosthesis (1) has two or more layers (5, 6, 7). At least one layer (5, 6, 7) includes a threadlike element (8) forming an armor (9). The luminal endoprosthesis (1) includes an anchoring portion (10) for anchoring to an anatomical portion (11) of the walls of the cavity (4) of the anatomical structure (3), and a working portion (12) for facing the pathological portion (13) of the anatomical structure (3). The two or more layers (5, 6, 7) are separated from each other in the working portion (12) of the luminal endoprosthesis (1), avoiding connecting elements between one layer (5, 6, 7) and at least one adjacent layer.

A device comprising: a tubular anchoring element configured and dimensioned for implanting about a multifurcation zone of a body lumen dividing a main vessel into at least two branches, to anchor the device therein; a removable sleeve defined by a tubular sidewall, the removable sleeve e being dimensioned for being removably received within a lumen of the anchoring element and extending therein at least the multifurcation zone, wherein the removable sleeve is self-expandable from a radially compressed state defining a delivery configuration into the anchoring element, to a radially expanded state defining a fully expanded configuration, wherein at least a portion of the sidewall, the portion encompassing at least inlets of the at least two branches, comprises a mesh having a mesh size sufficient to allow passage of blood and to deflect the flow of embolic material exceeding a predetermined size.

An anchor for a prosthetic heart valve includes a core, a first cover layer, and a second cover layer. The core includes a plurality of helical turns. One or more outflow turns of the plurality of helical turns has a diameter configured to be disposed on an outflow side of a native valve, and one or more inflow turns of the plurality of helical turns has a diameter configured to be disposed on an inflow side of a native valve. The first cover layer is disposed over and contacts the helical core, and the first cover layer includes a first material. The second cover layer is disposed over and contacts the first cover layer, and the second cover layer includes a second material, which is different than the first material.