The present disclosure relates to the field of endoscopy. Specifically, the present disclosure relates to systems and methods which allow the distal portion of a catheter to be visualized within the body using a colored marker and one or more secondary markers. In particular, the present disclosure relates to systems and methods which indicate when a medical device is properly positioned for deployment within a body lumen.

An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.

There is disclosed a synthetic joint stabilisation device (10) and associated assembly, the device having a particular use in a method of stabilising a dislocated acromioclavicular joint. The joint stabilisation device (10) comprises a first elongate portion (22) forming a first free end (24); a second elongate portion (26) forming a second free end (28) which is opposite the first free end; and an integral eye (30) provided at a location which is between the first and second free ends, the eye serving for securing the device to a bone (19) of a patient. The device (10) is at least partly tubular so as to define an internal cavity (32), said part, of the device being of a woven material. One of the first and second elongate portions (22, 26) extends into the internal cavity (32) through a wall (34) of the other one of the first and second elongate portions at a first location (36) along a length of said other portion, and then extends out of the internal cavity at a second location (38) which is spaced along a length of said other portion from the first location, to thereby form a loop (40) which defines the eye.

Tissue anchors, kits that include a tissue anchor, and methods of anchoring tissue to a bone are described. An example embodiment of a tissue anchor includes a screw and a stem releasably attached to the screw. The screw defines a first opening, a second opening, and a lumen that extends from the first opening to the second opening. A portion of the stem is sized and configured to be received within the lumen defined by the screw.

The invention relates to a device (1) and method for selecting the size and shape of a prosthesis and/or for determining the location of marks to be made on the external face of the skin of a patient intended to receive such a prosthesis, for example for repairing a hernia, comprising a sheet (2) of transparent material, the said sheet comprising: a plurality of graphical representations (3a, 3b, 4a, 4b, 5a, 5b, 5c, 5d) concentrically embodying the respective outlines of various shapes and sizes of prosthesis, a plurality of first holes (6a, 6b, 6c, 6d, 6e, 7a, 7b, 7c, 7d, 7e) arranged along the transverse line passing through the centre of the said sheet, and a plurality of second holes (8a, 8b, 8c, 8d, 8e, 8f, 8g, 9a, 9b, 9c, 9d, 9e, 9f, 9g) arranged along the longitudinal line passing through the centre (C) of the said sheet.

Embodiments of an implant for use in surgery are disclosed. The implant may include elastic polymer file made from a suitable biologically compatible polymer. The implant may also include a reinforcement element.

Tissue anchors, kits that include a tissue anchor, and methods of anchoring tissue to a bone are described. An example embodiment of a tissue anchor includes a screw and a stem releasably attached to the screw. The screw defines a first opening, a second opening, and a lumen that extends from the first opening to the second opening. A portion of the stem is sized and configured to be received within the lumen defined by the screw.

A method of inserting an intervertebral disc implant into a disc space includes accessing a spinal segment having a first vertebral body, a second vertebral body and a disc space between the first and second vertebral bodies. The method includes securing a first pin to the first vertebral body and a second pin to the second vertebral body, using the first and second pins for distracting the disc space, and providing an inserter holding the intervertebral disc implant. The method also desirably includes engaging the inserter with the first and second pins, and advancing the inserter toward the disc space for inserting the intervertebral disc implant into the disc space, whereby the first and second pins align and guide the inserter toward the disc space.

The present disclosure provides a system of gender specific pharmaceuticals. The system includes a first package of a pharmaceutical for use by a male and a second package of a pharmaceutical for use by a female. The first package includes a pharmaceutical for use by a male and a first label coupled to the first package, wherein at least one of the first package and first label includes a male specifier and a recommended male dosage. The second package includes a pharmaceutical for use by a female and a second label coupled to the second package, wherein at least one of the second package and second label includes a female specifier and a recommended female dosage.

An implant for insertion through a punctum and into a canalicular lumen of a patient. The implant includes a matrix of material, a therapeutic agent dispersed in the matrix of material, a sheath disposed over a portion of the matrix of material and configured to inhibit the therapeutic agent from being released from the matrix of material into the canalicular lumen and to allow the therapeutic agent to be released from a surface of the matrix of material to a tear film, and a retention structure configured to retain the implant within the canalicular lumen.