Prosthetic heart valves described herein can be deployed using a transcatheter delivery system and technique to interface and anchor in cooperation with the anatomical structures of a native heart valve. Some embodiments of prosthetic valves described herein include an anchor portion that couples to the anatomy near a native valve, and a valve portion that is mateable with the anchor portion. In some such embodiments, the anchor portion and/or the deployment system includes one or more prosthetic elements that temporarily augment or replace the sealing function of the native valve leaflets.

Embodiments of the present invention provide medical devices and methods for treating a target site within the body. For example, one embodiment provides a stent graft for treating a target site proximate to a bifurcated lumen, wherein the stent graft includes a first tubular structure having proximal and distal ends and a side wall extending therebetween. The first tubular structure includes an opening defined within the side wall and is configured to define a first portion having first and second ends and a second portion having first and second ends. The opening corresponds to the first ends of the first and second portions and the second ends of the first and second portions respectively correspond to the proximal and distal ends of the first tubular structure, and at least a portion of the first and second portions are configured to be positioned within respective branches of a bifurcated lumen.

The present invention provides a prosthetic heart valve device that has a frame, and a leaflet assembly having a plurality of leaflets that are secured to the frame. The frame is defined by an annular body and has three spaced-apart commissure regions, each commissure region having a commissure post extending from a proximal outflow end of the frame. A first clipping arm and a second clipping arm extend from opposite sides of each commissure post, each clipping arm extending from each commissure post at an obtuse angle with respect to each commissure post. Each clipping arm has a free end with a tip provided at the free end. The body has a first diameter at a location where the tips of the clipping arms are located, and the tips of the clipping arms extend away from define a second diameter, with the second diameter being greater than or equal to the first diameter.

A suture rigging assembly for use with a prosthetic heart valve delivery device includes a coupling ring having a plurality of apertures, and at least one tether coupled to the apertures of the coupling ring and extending distally therefrom. Each tether is formed by two lengths of suture thread, the lengths of suture thread joined together at a position spaced from the coupling ring, and a second joining of the lengths of suture thread forming an attachment loop at the distal end of the tether. The first connection in the tethers collectively define the shortest and longest lengths of each of the tethers, and the attachment loops provide a mechanism to releasably attach the tethers to a prosthetic heart valve. Optionally, knots can be used to join the tethers and one or more tethers may include a radiopaque marker secured thereon between two knots.

A radially expandable, tubular stent, includes a first section having a first crush resistance force and a second section have a second crush resistance force, wherein the first crush resistance force is less than the second crush resistance force. The first section is connected to the second section to form a tube, connection of the first and second sections extending in an axial direction of the tube.

A stent configured for implantation in a body lumen, includes: a tubular structure having a first end, a second end opposite from the first end, and a tubular body extending between the first end and the second end, the tubular body comprising a plurality of elongate portions defining a porosity for the stent, at least one of the elongate portions having a zig-zag configuration, the first end of the tubular structure having a plurality of crown elements disposed circumferentially with respect to a longitudinal axis of the tubular structure, the crown elements forming a crown configuration for the first end of the tubular body; and a plurality of tabs coupled to the first end of the tubular structure; wherein a number of the crown elements is higher than a number of the tabs; wherein the tabs are coupled to only a subset, and not all, of the crown elements.

A stent configured for implantation in a body lumen, includes: a tubular structure having a first end, a second end, and a tubular body, the tubular body comprising a plurality of elongate portions, the first end of the tubular structure having a plurality of crown elements; and a plurality of tabs coupled to the first end of the tubular structure; wherein the elongate portions comprise a first zigzag portion forming a first ring element, the first ring element having a first ring end, and a second ring end opposite from the first ring end, wherein the first ring end of the first ring element has a first set of peaks, and wherein the second ring end of the first ring element has a second set of peaks; and wherein the peaks in the first set are flat or are rectilinear.

The present invention relates to a stent graft for implantation in vessels of a patient, wherein the stent graft has a hollow cylindrical main body made of a first prosthesis material, with a proximal end and a distal end, with a longitudinal axis c and a circumference u, at least one pocket element which is made of a second prosthesis material and which is mounted circumferentially on the outer face and/or inner face of the main body in order to form a circumferential closed pocket on a longitudinal portion of the main body, and at least one stent element which extends in a meandering formation around the main body and is received inside the pocket element.

An annuloplasty device is disclosed for treating a defective mitral valve having an annulus, comprising a removable and flexible elongate displacement unit for temporary insertion into a coronary sinus (CS) adjacent the valve, wherein the displacement unit has a delivery state for delivery into the CS, and an activated state to which the displacement unit is temporarily and reversibly transferable from said delivery state, the displacement unit comprises a proximal reversibly expandable portion, a distal anchoring portion being movable in relation to the proximal expandable portion in a longitudinal direction of the displacement unit to said activated state in which the shape of the annulus is modified to a modified shape, wherein the proximal expandable portion is reversibly foldable to an expanded state for positioning against a tissue wall at the entrance of the CS.

Medical implants including sensors are described. The implant may have a flexible shell with a base, wherein the plurality of sensors may be incorporated onto and/or into the shell. The plurality of sensors may be distributed at different locations of the shell. Each sensor of the plurality of sensors may be configured to measure one or more parameters such as, e.g., temperature and/or pressure, and may comprise an electromagnetic coil useful for wireless transmission of data. Each sensor may be configured to transmit data at a frequency different from the frequency of one or more of the other sensors, may be configured to transmit data at a time different from a time data is transmitted by one or more of the other sensors, and/or may include a device identifier different from the device identifier of one or more of the other sensors.