Medical devices in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to expand.

Provided herein is a living bone graft including a biofabricated graft core including demineralized bone matrix and a carrier and a pre-vascularized shell at least partially enrobing the graft core, the pre-vascularized shell including isolated, intact adipose-derived microvessel fragments, mesenchymal stem cells, and collagen. The disclosed bone grafts include stromal cells that differentiate and microvessels that inosculate to provide a functional microvasculature, thereby approximating native bone repair as the graft matures in the patient. Also provided herein are methods of fabricating a bespoke, living, vascularized bone graft and methods of treating a segmental bone defect in a patient.

Medical devices in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to expand.

An improved mechanism for expanding or lifting a device in accordance with various embodiments of the present invention is a coaxial screw gear sleeve mechanism. In various embodiments, coaxial screw gear sleeve mechanisms includes a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing a device utilizing such a mechanism to expand or lift between a collapsed configuration and an expanded configuration.

An improved mechanism for expanding or lifting a device in accordance with various embodiments of the present invention is a coaxial screw gear sleeve mechanism. In various embodiments, coaxial screw gear sleeve mechanisms includes a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing a device utilizing such a mechanism to expand or lift between a collapsed configuration and an expanded configuration.

A surgical implant (20) comprises a flexible, areal basic structure (22) having a first face and a second face and being provided with pores (26) extending from the first face to the second face. A barrier layer (24) having a first face and a second face is placed, with its second face, at the first face of the basic structure (2) and attached to the basic structure (22). The barrier layer (24) is deformed into at least part of the pores (26) where it forms, in a respective pore (10), a barrier region (28).

Medical devices in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to expand.

Fibrocartilage implants characterized by circumferential fiber networks embedded in arcuate or torroidal scaffolds with orthogonal fiber networks embedded therein to prevent separation of the circumferential fiber networks. The fiber networks convert axial compressive forces on the scaffolds to tensile loads on the circumferential fibers. Artificial knee meniscus and vertebral disc implants are disclosed, as well as articular disc implants for joints such as the temporomandibular joint and wrist. Methods for implanting the fibrocartilage devices are also disclosed.

Medical devices in accordance with various embodiments of the present invention employ one or more coaxial screw gear sleeve mechanisms. In various embodiments, coaxial screw gear sleeve mechanisms include a post with a threaded exterior surface and a corresponding sleeve configured to surround the post, the corresponding sleeve having a threaded interior surface configured to interface with the threaded exterior surface of the post and a geared exterior surface. A drive mechanism can be configured to interface with the geared exterior surface of the sleeve, causing the device to expand.

A method for removing a basivertebral nerve (BVN), includes the following sequential steps. First, inserting a bone needle into a vertebral body of a vertebra and advancing the bone needle under fluoroscopy to a BVN base site. The bone needle includes an elongated shaft having a cannula extending from a proximal end to a distal end of the shaft, and a removable bevel tipped inner stylet extending through the cannula. Next, removing the inner stylet from the cannula and inserting a drill/awl through the cannula into the BVN base site and once the drill/awl position and depth is confirmed via fluoroscopy drilling the BVN base out. Next, removing the drill/awl from the cannula and inserting a cup curette through the cannula into the BVN base site to further resect under fluoroscopy the BVN base. Next, removing the cup curette from the cannula and inserting a pituitary rongeur through the cannula into the BVN base site and removing under fluoroscopy all resected portions of the BVN base. Next, removing the pituitary rongeur from the cannula and inserting an electric ablation probe through the cannula into the BVN base site and once the ablation probe depth and position is confirmed ablating and cauterizing any remaining BVN base and forming a lesion in the BVN site. Next, removing the ablation probe from the cannula and inserting a nerve monitoring probe through the cannula into the BVN base site and testing to ensure that the BVN base has been fully removed from the BVN site and a void has been formed. Next, removing the nerve monitoring probe from the cannula and attaching a syringe filled with bone graft to the proximal end of the shaft, and filling the void formed in the BVN site with bone graft.