A41D2400/32

PHOTOSENSITIZING ANTIBODY-FLUOROPHORE CONJUGATES

The present disclosure relates to compositions and methods of killing cells in vitro or in vivo. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein. In particular examples the antibody recognizes a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm.sup.2, thereby killing the cell. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods.

Radiation protection device and methods thereof

A radiation protection device for providing protection of a body part that includes active bone marrow from ionizing radiation may include a radiation protection component configured to be placed adjacent to and externally cover the body part so as to reduce a radiation dose absorbed in that body part.

PHOTOSENSITIZING ANTIBODY-FLUOROPHORE CONJUGATES

The present disclosure relates to compositions and methods of killing cells. In particular examples, the method includes contacting a cell having a cell surface protein with a therapeutically effective amount of an antibody-IR700 molecule, wherein the antibody specifically binds to the cell surface protein, such as a tumor-specific antigen on the surface of a tumor cell. The cell is subsequently irradiated, such as at a wavelength of 660 to 740 nm at a dose of at least 1 J cm.sup.2. The cell is also contacted with one or more therapeutic agents (such as an anti-cancer agent), for example about 0 to 8 hours after irradiating the cell, thereby killing the cell. Also provided are methods of imaging cell killing in real time, using fluorescence lifetime imaging. Also provided are wearable devices that include an article of clothing, jewelry, or covering; and an NIR LED incorporated into the article, which can be used with the disclosed methods.

Therapeutic clothing having sensory strips and stress relieving components incorporated therein
10589058 · 2020-03-17 ·

Therapeutic clothing includes a garment adapted to be worn over a lower portion of a body having a waistband and first and second legs extending below the waistband. The therapeutic clothing has a first elongated sensory strip attached to an outside surface of the first leg and extending along the length of the first leg between the waistband and a lower end of the first leg. The first elongated sensory strip has an inner edge attached to the outside surface of the first leg and a free outer edge. The therapeutic clothing has a second elongated sensory strip attached to an outside surface of the second leg and extending along the length of the second leg between the waistband and a lower end of the second leg. The second sensory strip has an inner edge attached to the outside surface of the second leg and a free outer edge.

Sleep apnea prevention mask
10582732 · 2020-03-10 · ·

A sleep apnea prevention sleep-aid mask is described. The sleep-aid mask is configured to secure the lips of a user together in a natural state, in order to encourage the respiratory system of the user to employ the nasal passages rather than the mouth for respiration. A pad equipped with a perforated mesh or channel is positioned over the lips and mouth of the user, and secured in position on the user via an adhesive, which temporarily affixes the pad to the face of the user. The sleep-aid mask is preferably shaped and sized according to the specific size of the user's face, and is configured to limit the effective diameter of the mouth of the user, in order to cause continued use of respiration via the nasal passages.

Topical Therapeutics
20200054887 · 2020-02-20 ·

The present invention classifies disorders, including Local Anesthetic Responsive Headaches as a general class. The present invention also uses exclusion and inclusion criteria in order to better determine the proper treatment of disorders including dorsonasal targeted therapies.

Article of Clothing with Magnets
20200046038 · 2020-02-13 ·

An article of clothing with magnets. The article of clothing with magnets is at least one material configured to receive a body part of a user, as well as at least one magnet disposed on the material. In various embodiments, the at least one magnet can be comprised of magnetic discs or magnetic strips. The article of clothing can cover the entire body, or various parts of an individual's body. In another embodiment, the at least one magnet is disposed on the inner layer such that it is in contact with a wearer's skin. In various embodiments, the at least one magnet is disposed at a plurality of meridian lines, a plurality of pressure points, a plurality of muscle groupings, a plurality of acupuncture points, or combinations thereof.

ARM COVER GLOVE DEVICE FOR PROTECTING THE REMOVAL OF INTRAVENOUS ACCESS DEVICE AND METHOD OF USE THEREOF
20200029634 · 2020-01-30 ·

An arm cover glove device for protecting the removal of an intravenous access device includes a sleeve portion, a glove portion and a securing system. The sleeve portion is configured to go around an arm of a patient. The sleeve portion includes an open top end configured to receive and cover an arm of the patient into a hollow interior of the sleeve portion, and a bottom end. The glove portion is connected to the bottom end of the sleeve portion. The glove portion is configured to receive and cover the hand of the patient. The sleeve portion and the glove portion are configured to cover the intravenous access device while connected to the arm or hand of the patient. The securing system is configured to keep the patient from removing the arm cover glove device.

GARMENT SYSTEM PROVIDING BIOMETRIC MONITORING FOR MEDICAL CONDITION ASSESSMENT

A garment (e.g., a shirt) for monitoring biometric properties of the wearer of the garment is disclosed. The garment may include sensors for monitoring or assessing the vital signs and body position of the wearer. A processor associated with the garment may provide an output indicative of an assessed condition of the wearer based on the assessed vital signs and the assessed body position of the wearer of the fabric. The garment may include an injector assembly that is used to administer a drug injection to the wearer when the assessed condition indicates that the wearer is in an alert condition.

Belt additional substance having self-heating and functionality using graphene and nano inorganic substance, and belt and manufacturing method using the same
10543120 · 2020-01-28 ·

A method for manufacturing a belt, which molds a heating member 13 by 20 to 98 parts by weight selecting at least one of nonferrous metals constituted by tourmaline, bentonite, pozzolan, mica, red clay, zeolite, magnesium oxide, white clay, calcium, and silica, 0.1 to 30 parts by weight selecting at least one of A type Tio sol, Ag sol, and Zno having a particle size of 5 to 20 nm, graphene 01 to 10 parts by weight having a particle size of 0.20 to 2.25 nm, and functional metal colloidal 0.05 to 8 parts by weight having a size of 1 to 10 nm by selecting at least one of Ag, Au, Zn Pt, and Y, 20 to 98 parts by weight are combined by selecting at least one of the nonferrous metals and thereafter, ground into particle sizes of 500 to 1500 meshes.