Systems and methods are disclosed that facilitate obtaining two dimensional (2D) ultrasound images, using two or more ultrasound imaging modes or modalities, to generate 2D multi-parametric ultrasound (mpUS) images and/or to generate a three-dimensional (3D) mpUS image. The different ultrasound imaging modes acquire images in a common frame of reference during a single procedure to facilitate their registration. The mpUS images (i.e., 2D or 3D) may be used for enhanced and/or automated detection of one or more suspicious regions. After identifying one or more suspicious regions, the mpUS images may be utilized with a real-time image to guide biopsy or therapy the region(s). All these processes may be performed in a single medical procedure.

An inverse visualization of a time-resolved angiographic image data set of a vascular system of a patient that was recorded by a medical imager during the flow of a contrast medium through the vascular system is provided. The time-resolved angiographic image data set of the vascular system has a temporal sequence of frames of the vascular system corresponding to the contrast medium filling process. A data set from bolus arrival times for each pixel or voxel is determined. The bolus arrival time corresponds to the time in the temporal sequence at which a predetermined contrast enhancement due to the contrast medium filling first occurs. A data set of temporally inverted bolus arrival times with respect to the contrast medium filling is determined for each pixel or voxel, resulting in a temporally inverted sequence of frames with respect to the contrast medium filling. The time-resolved angiographic image data set in the temporally inverted sequence is visualized.

A computer implemented method for generating a 3D printable model of a patient specific anatomic feature from 2D medical images is provided. A 3D image is automatically generated from a set of 2D medical images. A machine learning based image segmentation technique is used to segment the generated 3D image. A 3D printable model of the patient specific anatomic feature is created from the segmented 3D image.

Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Methods and apparatus for predicting performance of an individual on a task, the method comprises receiving brain imaging data for the individual, wherein the brain imaging data comprises structural brain data, determining values for at least one characteristic of the structural brain data within regions of interest defined for a population of individuals having different performance levels, and predicting based on the determined values, a performance potential of the individual.

A system includes a processor circuit configured for communication with an external imaging device. The processor circuit receives, from the external imaging device, an image comprising a blood vessel within a patient. The processor circuit determines, using the image, a first location of the blood vessel with a restriction in blood flow caused by compression of the blood vessel by an anatomical structure within the patient and different than the blood vessel. The processor circuit generates a first graphical representation associated with the restriction. The processor circuit outputs, to a display in communication with the processor circuit, a screen display. The screen display includes the image and the first graphical representation at the first location of the blood vessel in the image.

The image processing apparatus acquires a plurality of types of candidate images based on an endoscope image, performs control of displaying, on a display, a display image based on at least one type of candidate image, performs a first analysis process on one or the plurality of types of candidate images set in advance, selects at least one type of candidate image from the plurality of types of candidate images as an optimum image based on a first analysis process result obtained through the first analysis process, and obtains a second analysis process result by performing a second analysis process on the optimum image.

Methods and systems are provided for assessing a vasculature of an individual. In an embodiment of a method, one or more angiographic parametric imaging (API) maps of the vasculature are obtained, wherein each API map of the one or more API maps encodes a hemodynamic parameter. A state of the vasculature is determined using a machine-learning classifier applied to the one or more API maps.

Systems and methods for analysis of a whole blood sample from an individual to determine the platelet function and coagulation status of the individual in a substantially automated and efficient matter. Also provided here are systems, reagent kits, and methods for concurrent assessment of platelet function and coagulation as they interact during hemostasis.

The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, perform computational fluid dynamics analysis, facilitate assessment of risk of heart disease and coronary artery disease, enhance drug development, determine a CAD risk factor goal, provide atherosclerosis and vascular morphology characterization, and determine indication of myocardial risk, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.