A method for imaging a coronary arterial system of an individual includes releasing, using an actuator, pulses of a radio-opaque dye into a coronary arterial tree of the individual. The method further includes obtaining, using an image capture device, a sequence of invasive coronary x-ray angiogram images over time of the pulses of the radio-opaque dye. The method also includes tracking, using a processor, the pulses through the sequence of invasive coronary x-ray angiogram images and locating the pulses on a three dimensional (3D) structural model of the coronary arterial system to generate a three dimensional (3D) functional model of the coronary arterial system that shows a trajectory of the dye as it flows through different arterial branches.

A method and apparatus for vascular assessment are disclosed. The apparatus, in some embodiments, receives a plurality of 2-D angiographic images of a portion of a vasculature of a subject, and processes the images to produce a stenotic model over the vasculature. The stenotic model has measurements of the vasculature at one or more locations along vessels of the vasculature. The apparatus, in some embodiments, determines a flow characteristic of the stenotic model and calculates an index indicative of vascular function, based, at least in part, on the flow characteristic in the stenotic model.

A system and method for determining a trajectory parameter of particles, comprising receiving a plurality of particles at a microfluidic channel, applying a force to each particle of the microfluidic channel, acquiring a dataset of each particle, measuring a trajectory of the particle, and determining a trajectory parameter of the particles.

A method for processing blood pressure measurement includes obtaining a facial feature point of an object, determining a first height difference between the facial feature point and an origin of a second coordinate system based on a first coordinate of the facial feature point in the second coordinate system and a first attitude angle of the second coordinate system relative to a first coordinate system, determining a third height difference between the origin of the second coordinate system and the heart of the object based on the first height difference and a second height difference, where the second height difference is a height difference between the facial feature point and the heart of the object, and determining blood pressure based on a blood pressure measurement signal of the object and the third height difference.

The disclosure provides a method and system for determining a lumen volume of a target blood vessel. The method may include acquiring a temporal sequence of angiography images of the target blood vessel after a contract agent is injected in the target blood vessel. The method may further include identifying a region of interest containing the target blood vessel, by a processor, in each angiography image in the temporal sequence of angiography images. The method may also include integrating, by the processor, pixel values in each region of interest, and determining the lumen volume, by the processor, based on the integrated values of the regions of interest and a predetermined correlation between the integrated values and volumes of the contrast agent.

Provided in the present application are a method and a device for extracting a blood vessel wall, a medical imaging system, and a non-transitory computer-readable storage medium. The method for extracting a blood vessel wall comprises acquiring a medical image, determining at least one first-order feature in the medical image, and extracting, on the basis of the at least one first-order feature, a blood vessel wall image from the medical image.

A method, an apparatus and a system for conveniently measuring coronary artery vascular evaluation parameters are provided by the disclosure. The measurement method includes: measuring a pressure P.sub.d at a distal end of coronary artery stenosis and/or a pressure P.sub.a at a coronary artery inlet via a pressure guide wire (S100); performing coronary angiography for a blood vessel to be measured (S200); selecting an angiogram image of a first body position and an angiogram image of a second body position of the blood vessel to be measured (S300); selecting a segment of blood vessel from a proximal end to a distal end of the coronary artery for segmentation, and obtaining a three-dimensional coronary artery vascular model by three-dimensional modeling (S400); injecting a contrast agent, and obtaining an average time T.sub.a taken for the contrast agent passing from an inlet to an outlet of the segment of blood vessel (S500); obtaining a time T.sub.max taken for the contrast agent passing from the inlet to the outlet of the segment of blood vessel in a maximum dilated state according to hydrodynamic formulas (S600); obtaining coronary artery vascular evaluation parameters (S700).

System and method for evaluating the vascular health condition of a subject using thermal imaging is disclosed. The system and method includes capturing passive thermal images and/or videos of at least one body part, detecting a predefined region of the body part in each frame of the captured images/videos, and segmenting one or more portions from the detected predefined region in each frame of the captured images/videos. Further a region of interest comprising blood vessels in the segmented portions in each frame of the captured images/videos is identified to extract pixel values from each frame of the captured images/videos representing biosignals. Parameters associated with the potential biomarkers of vascular functions and hemodynamics of the subject are determined based on the extracted pixel values representing biosignals. The vascular health condition of the subject is evaluated based on deviation of the determined parameters with respect to predetermined reference parameters.

The present invention relates to the field of medical imaging in the absence of contrast agents. In one form, the invention relates to the field of imaging vessels, particularly blood vessels such as the pulmonary vasculature and is suitable for use as a technique for detecting pulmonary embolism (PE), such as acute PE. Embodiments of the present invention provide improved image processing techniques having the capability to extract and use image data to overcome the need for contrast agents to distinguish between different types of tissue. Furthermore, it has also been realised that the image data accessed by the improved image processing can be used to identify irregularities in vessels.

A time-series morphology index and a time-series shape deformation index of the analysis target region on a time-series medical image are calculated by image processing. A dynamical model of a structural fluid analysis of the analysis target region is temporarily structured, based on the time-series morphology index, the time-series shape deformation index, and the time-series medical image. A latent variable of the identification region is identified so that at least one of a prediction value of a blood vessel morphology index and a blood flow volume index based on the temporarily structured dynamical model match with at least one of an observation value of the blood vessel morphology index and the blood flow volume index measured.