Images of individuals obtained using perfusion-based imaging techniques or diffusion-based imaging techniques can be analyzed to determine regions of the brains of the individuals where the supply of blood has been disrupted. The images can be used to generate alerts indicating the disruption of blood flow to one or more regions of the brains of the individuals. The images can be used to identify vessel segments (eg M1, M2, M3, M4, . . . ) and branches (MCA, ACA, PCA) of the brains of individuals in which abnormalities may be present.

A method for detecting vascular obstruction and a system using the same are provided. The method includes steps of: detecting a blood vessel through a probe to generate a reference signal before the blood vessel is obstructed, wherein the probe is configured to transmit or receive ultrasonic waves; detecting the blood vessel through the probe to generate a detection signal; performing Fourier transformation on the reference signal to generate a reference power spectrum, and performing Fourier transformation on the detection signal to generate a detection power spectrum; transforming the reference power spectrum into a reference time-frequency spectrogram, and transforming the detection power spectrum into a detection time-frequency spectrogram; judging a similarity between the reference time-frequency spectrogram and the detection time-frequency spectrogram, and judging whether the blood vessel is obstructed or not according to the similarity.

Images can be generated indicating damaged brain tissue based on the disruption of blood supply. First imaging data can be generated by a first imaging technique that can be a vascular imaging technique, such as CT-perfusion imaging or CT angiography. Second imaging data can be generated by a second imaging technique that can be a non-perfusion-based imaging technique, such as non-contrast CT imaging, or the unenhanced portion of a CT-perfusion imaging examination. Intensity values of voxels of the first imaging data can be analyzed to determine a first region of interest in which brain tissue damage may be present. Intensity values of voxels of the second imaging data can be analyzed to determine a second region of interest in which brain tissue damage may be present. An aggregate image including overlays corresponding to the first region of interest and the second region of interest can be generated.

An apparatus for classifying a brain tissue area as functional or non-functional by a stimulation of the brain includes a receiver unit for receiving information about a performed stimulation, a recording device for recording images that represent the brain tissue area, a detection unit for detecting a change in perfusion in the brain tissue area, and a classification unit configured to determine with the information whether there is a correlation between the performed stimulation and the detected change in perfusion, and to classify the brain tissue area as functional or as non-functional. The recording device is an endomicroscope for recording endomicroscopic images of the brain tissue area with a spatial resolution better than 20 μm and a frame rate of at least 0.4 frames per second. The detection unit is configured to detect a change in perfusion based on the positions of certain tissue structures in the recorded images.

A medical image-processing apparatus according to embodiments includes processing circuitry. The processing circuitry is configured to acquire image data including a blood vessel of a subject. The processing circuitry is configured to acquire an index value relating to blood flow at each position of the blood vessel by performing fluid analysis of a structure of the blood vessel included in the acquired image data. The processing circuitry is configured to acquire information indicating a display condition of the index value, as switching information to switch a display mode at displaying the index value. The processing circuitry is configured to generate a result image in which pixel values reflecting the index value are assigned in a display mode according to the switching information, for an image indicating a blood vessel of the subject. The processing circuitry is configured to cause a display to display the result image.

A system for measurements and calculations of a microcirculatory high-velocity blood flow includes a data acquisition module configured to select and acquire microcirculatory blood vessel image data; a storage module configured to store the acquired microcirculatory blood vessel image data; a velocity measurement module configured to measure a traveling distance and a traveling time of red blood cell (RBC), white blood cell (WBC), or plasma particles in a blood vessel sample and calculate a ratio of the traveling distance to the traveling time to obtain a blood flow velocity; and a high-velocity blood flow index module configured to determine an index level for the microcirculatory high-velocity blood flow. Specifically, an initial threshold, i.e. 1000 μm/s, for the microcirculatory high-velocity blood flow of sepsis is proposed, which facilitates early diagnosis on sepsis. The changing process of the high-velocity blood flow shows development of the early-stage, intermediate-stage and end-stage sepsis.

An actual measurement value calculation unit calculates a first actual measurement value of oxygen saturation of a tissue to be observed. A reference value calculation unit calculates a first reference value of the oxygen saturation of the tissue to be observed. A relative value calculation unit calculates a relative value of the first actual measurement value with reference to the first reference value. An image generation unit generates an image of the relative value of the first actual measurement value on the basis of an evaluation color table to generate an evaluation oxygen-saturation image. A display unit displays the evaluation oxygen-saturation image.

Pulsed hyperspectral imaging in a light deficient environment is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes a plurality of bidirectional pads comprising an output state for issuing data and an input state for receiving data. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises electromagnetic radiation having a wavelength from about 513 nm to about 545 nm, from about 565 nm to about 585 nm, or from about 900 nm to about 1000 nm.

The embodiment of the invention discloses an intraoperative blood flow imaging method based on fluorescence imaging and belongs to the technical field of medical fluorescence imaging. The present invention effectively removes shadow or tissue pulsation interference by utilizing the fluorescence imaging images to identify the blood flow area; and meanwhile, by conducting pseudo-color imaging on the blood flow area, as a pseudo-color value has correlation with a blood flow perfusion time, the present invention may accurately indicate the blood flow areas in the images and is easy to distinguish the blood flow areas.

Systems and methods of predicting future medical events are based on the processing of medical image. The prediction of premature birth and estimation of gestational age based on ultrasound images are presented as illustrative examples. The new abilities to estimate the probability of future medical events, before they otherwise could be predicted, provides new avenues for the development of preventative treatments.