A device of an embodiment includes: an optical mechanism that guides light from a light source to skin tissue to scan the skin tissue; a control computation unit that controls driving of the optical mechanism, acquires tomographic images of the skin by processing optical interference signals from the optical system, and calculates a network of blood vessels on the basis of the tomographic images; and a display device that displays the network of blood vessels. The control computation unit computes autocorrelation values at coordinates in epidermis corresponding regions of the tomographic images, excludes combinations of tomographic images with the computed autocorrelation values corresponding to predetermined low autocorrelation, computes autocorrelation values at coordinates in dermis corresponding regions, determines coordinates at which the autocorrelation values in the dermis corresponding regions are within a predetermined low correlation range to be blood vessels or blood vessel candidates, and calculates a network of blood vessels.

In part, the disclosure relates to methods, and systems suitable for evaluating image data from a patient on a real time or substantially real time basis using machine learning (ML) methods and systems. Systems and methods for improving diagnostic tools for end users such as cardiologists and imaging specialists using machine learning techniques applied to specific problems associated with intravascular images that have polar representations. Further, given the use of rotating probes to obtain image data for OCT, IVUS, and other imaging data, dealing with the two coordinate systems associated therewith creates challenges. The present disclosure addresses these and numerous other challenges relating to solving the problem of quickly imaging and diagnosis a patient such that stenting and other procedures may be applied during a single session in the cath lab.

A method of treating a human patient identified as having an injury to a body region includes receiving CT images, where the CT images were generated by performing a CT angiography of an injured body region of the human patient. The method further includes determining, based on the CT images, a total volumetric rate of active bleeding in the injured body region; and recommending at least one treatment approach for the human patient based on the total volumetric rate of active bleeding.

A medical-information processing apparatus according to an embodiment includes processing circuitry. The processing circuitry acquires medical image data that is obtained during imaging on the subject in a resting state in the time phase where the relationship between the volume of blood flow and the pressure in a blood vessel in the cardiac cycle of the subject indicates a proportional relationship. The processing circuitry extracts the structure of a blood vessel, included in the medical image data, applies fluid analysis to the structure of the blood vessel to obtain a first index value, which is obtained based on the pressure in the blood vessel on the upstream side of a predetermined position within the blood vessel and the relation equation between the volume of blood flow and the pressure in the blood vessel in the resting state, and a second index value, which is obtained based on the pressure in the blood vessel on the downstream side of the predetermined position and the relation equation, and calculates the pressure ratio, which is the ratio of the first index value to the second index value.

Systems, methods, and devices for generating ultrasound images that have reduced or minimized grating lobe artifacts are provided. In one embodiment, an ultrasound imaging system includes an array of acoustic elements, and a processor in communication with the array. The processor is configured to receive electrical signals from the array, determine, based on the directivity of the acoustic elements, a portion of the electrical signals corresponding to on-axis components, generate a weighting mask based on the portion, and apply the weighting mask to an original image to generate a grating lobe minimized image. Because grating lobe artifacts are caused, in part, by reflections from off-axis objects, applying the weighting mask to an original image can reduce the presence of grating lobe artifacts in the original image.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a DHM image acquired using a digital holographic microscopy system and identifying one or more erythrocytes in the DHM image. For each respective erythrocyte included in the one or more erythrocytes, a cell thickness value for the respective erythrocyte using a parametric model is estimated, and a cell volume value is calculated for the respective erythrocyte using the cell thickness value.

The present invention provides a method of detecting microbubbles in a vessel of an affected part, comprising aggregates the microbubbles, acquiring phase-contrast magnetic resonance images and analyzing the phase-contrast magnetic resonance images. Thus, we can detect or monitor the size and location of the microbubbles in vessels of any part of body.

A system and method for camera-based heart rate tracking. The method includes: determining bit values from a set of bitplanes in a captured image sequence that represent the HC changes; determining a facial blood flow data signal for each of a plurality of predetermined regions of interest (ROIs) of the subject captured by the images based on the HC changes; applying a band-pass filter of a passband approximating the heart rate to each of the blood flow data signals; applying a Hilbert transform to each of the blood flow data signals; adjusting the blood flow data signals from revolving phase-angles into linear phase segments; determining an instantaneous heart rate for each the blood flow data signals; applying a weighting to each of the instantaneous heart rates; and averaging the weighted instantaneous heart rates.