Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.

An apparatus for vascular modeling is disclosed. The apparatus receives medical images from an imaging device that include representations of a coronary vessel tree of a subject recorded at a different viewing angles. The apparatus determines, from a first of the medical images, a first centerline set and first vessel diameters for sample points along the first centerline set, and determines, from a second of the medical images, a second centerline set and second vessel diameters for sample points along the second centerline set. The apparatus determines a correspondence between the first centerline set and the second centerline set, and determines diameters for a combined centerline set based on the correspondence of sample points along the first and second centerline sets. The apparatus provides the combined centerline set for estimating blood flow resistance values of the coronary vessel tree of the subject to determine at least one potential stenosis.

An automatic clipping technique capable of satisfactorily extracting blood vessels to be extracted is provided. A specific tissue extraction mask image which is created by extracting a specific tissue (for example, a brain) from a three-dimensional image acquired by magnetic resonance angiography and a blood vessel extraction mask image which is created by extracting a blood vessel from an area (a blood vessel search area) which is determined using a preset landmark position and the specific tissue extraction mask image are integrated to create an integrated mask. By applying the integrated mask to the three-dimensional image, a blood vessel is clipped from the three-dimensional image.

Systems and methods are provided for automatic detection and quantification for traumatic bleeding. Image data is acquired using a full body dual energy CT scanner. A machine-learned network detects one or more bleeding areas on a bleeding map from the dual energy CT scan image data. A visualization is generated from the bleeding map. The predicted bleeding areas are quantified, and a risk value is generated. The visualization and risk value are presented to an operator.

A dynamic analysis system includes a hardware processor. The hardware processor: analyzes a dynamic image for a dynamic state of a living body; generates an analysis result image showing the analysis result; determines, for each pixel of the dynamic image or the analysis result image, whether a pixel value is within a predetermined range of values; classifies the pixels into groups according to the determination result; extracts, as each border pixel, a pixel in a group adjacent to a pixel classified into a different group; generates a border between the groups based on the extracted border pixels; superimposes the border on, between the dynamic image and the analysis result image, an image not subjected to the classification, thereby generating a combined image; and causes an output device to output the combined image.

Detecting a pulmonary embolism (PE) in an image dataset of a blood vessel involves obtaining a volume of interest (VOI) in the blood vessel, generating a plurality of PE candidates within the VOI, generating a set of voxels for each PE candidate, estimating for each PE candidate an orientation of the blood vessel that contains the PE candidate, given the set of voxels for the PE candidate, and generating a visualization of the blood vessel that contains the PE candidate using the estimated orientation of the blood vessel that contains the PE candidate.

An image synthesis unit of an X-ray imaging apparatus is configured to correct a synthesis target image or a transparent image based on movement information of a feature point and movement information of a pixel and generate a synthesized image by synthesizing a corrected synthesis target image and a transparent image or synthesizing a synthesis target image and a corrected transparent image.

An image acquisition unit acquires a CT image and one or more MRI images of the brain of a subject that has developed a cerebral infarction. An infarction region extraction unit extracts an infarction region corresponding to the time elapsed since the development from the MRI image. A registration unit performs registration between the CT image and the MRI image. An infarction region specification unit specifies the infarction region corresponding to the time elapsed since the development in the CT image on the basis of the result of the registration. A learning unit learns a discriminator which discriminates an infarction region corresponding to the time elapsed since the development in the CT image to be discriminated, using the infarction region corresponding to the time elapsed since the development, which has been specified in the CT image, as teacher data.

A computer-implemented method of reducing 4D Digital Subtracted Angiography (DSA) reconstruction artifacts using a computational fluid dynamics (CFD) simulation includes a computer receiving first DSA time sequence data comprising a representation of a plurality of vessels and segmenting a vessel of interest from the first DSA time sequence data. The computer uses the CFD simulation to simulate fluid dynamics across the vessel of interest to yield a flow field and determines a plurality of simulated time activity curve parameters for each voxel inside the vessel of interest using the flow field. Then, the computer applies a reconstruction process to second DSA time sequence data to yield a DSA volume. This reconstruction process is constrained by the plurality of simulated time activity curve parameters for each voxel inside the vessel of interest.

The present disclosure relates to a device, a system, and a computer-readable medium for calculating vessel flow parameters based on angiography. In one implementation, the device includes a processor and a memory storing computer-executable instructions that, when executed by the processor, cause the processor to perform the following operations: selecting a plurality of template frames from the angiographic images to generate a 3D model for a vessel; determining a start frame and an end frame in the plurality of angiographic images showing a contrast filling process; determining corresponding locations of front ends of the contrast in the start frame and the end frame in the 3D model of the vessel; calculating a vessel volume between the determined locations of the front ends in the 3D model; and determining an average blood flow rate based on the calculated volume, and a time interval between the start frame and the end frame.