The invention disclosed provides means of inhibiting, ameliorating, and/or treatment of rheumatoid arthritis through the use of Noble gas containing mixtures. In one embodiment, the invention provides means of reducing inflammation and immune associated pathology through administration of Noble gas mixtures. In one specific embodiment, Xenon gas is administered to a patient in need at concentrations and frequencies sufficient to inhibit inflammatory and autoimmune processes. In another embodiment Noble gas mixtures are administered to reduce pain and provide symptomatic relieve to a patient suffering from rheumatoid arthritis. In another embodiment the use of Noble gas containing mixtures is disclosed as a means of reducing joint destruction through inhibition of matrix metalloprotease production and activity.

Disclosed are the unique and unexpected findings that xenon gas possesses the ability to directly inhibited amyloid beta associated toxicity, inhibit production of amyloid beta, and stimulate synthesis of soluble, free-form amyloid beta. The invention teaches the use of xenon gas, as well as various combinations of Noble Gases, for the prevention, amelioration, and treatment of Alzheimer's Disease and other pathologies associated with generation of insoluble aggregates containing amyloid beta.

The present invention provides systems, methods, and apparatus for applying a hyperoxic therapy delivery system to a patient; administering hyperoxic gas to the patient according to an oxygen dose-response model; and adjusting the administration of the hyperoxic gas to the patient based upon monitored parameters related to a condition of the patient. Numerous additional features are disclosed.

A portable hyperbaric chamber device with forward-facing door includes a frame, an inflatable chamber, a dump valve, at least one primary pressure relief valve, at least one secondary pressure relief valve, a plurality of fill valves. Access to the inflatable chamber is gain through a door panel of the inflatable chamber. The inflatable chamber is positioned within and secured to the frame. The plurality of fill valves is in fluid communication with the inflatable chamber so that the inflatable chamber can be pressured for usage. The dump valve is in fluid communication with the inflatable chamber to deflate the inflatable chamber. The primary pressure relief valve and the secondary pressure relief valve are in fluid communication with the inflatable chamber to maintain a safe internal pressure within the inflatable chamber to protect wellbeing of the users and the structural integrity of the complete apparatus.

A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and without glycolytic therapies. The patient is subjected to a hyperbaric environment of substantially pure oxygen. A predetermined dose of one or more HDACI substances is administered to the patient. In addition, glycolitic inhibitors may also be administered. Dosages, pressures, and durations are selected as described herein to have a therapeutic effect on the patient.

An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

The present invention relates to an adaptive hyperbaric oxygen chamber designed to function as a medical apparatus in order to treat a subject suffering from any FDA approved medical condition. The hyperbaric oxygen chamber is designed and constructed in such a way that only one subject can be allowed to sit in an upright seated position, unless the pediatric seat is occupied by a pediatric patient and the adult is seated in the standard seat to accompany the pediatric patient. The upright patient seat when treating a pediatric patient is in the extended position while the occupant enters and exits the mono medical hyperbaric oxygen chamber and the seat is returned to the fixed position inside the hyperbaric oxygen chamber while the overhead door is closed, the seat being operated by an extension device. The hyperbaric oxygen chamber is made, using additive manufacturing technology. The hyperbaric oxygen chamber provides two hundred to five hundred liters of one hundred percent oxygen per minute to the pressure vessel. A nitrogen scrubber is connected to a discharge air duct of this hyperbaric oxygen chamber that converts the oxygen being expelled through the air duct to one hundred percent nitrogen.

An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

The embodied invention is a hyperbaric chamber that is designed to fit through a narrower dimension, such as a doorway, window, garage, or hallway by utilizing a multi-section design. The preferred embodiment is a split chamber design that allows two or three sections to be moved by caster wheels, either on the legs with casters or on a moving cart. The width of the separate sections is designed to fit through a 34″ doorway, and then are readily bolted together to a desirable length. Additionally, the flanges design that connect the individual vessel parts together are designed to provide the pressure needed at a very low weight.

The embodied invention is a hyperbaric chamber that is designed to fit through a narrower dimension, such as a doorway, window, garage, or hallway by utilizing a multi-section design. The preferred embodiment is a split chamber design that allows two or three sections to be moved by caster wheels, either on the legs with casters or on a moving cart. The width of the separate sections is designed to fit through a 34″ doorway, and then are readily bolted together to a desirable length. Additionally, the flanges design that connect the individual vessel parts together are designed to provide the pressure needed at a very low weight.