A method for treating cancer is described using combination therapies comprising the use of hyperbaric oxygen with histone deacetylase inhibitors, with and without glycolytic therapies. The patient is subjected to a hyperbaric environment of substantially pure oxygen. A predetermined dose of one or more HDACI substances is administered to the patient. In addition, glycolitic inhibitors may also be administered. Dosages, pressures, and durations are selected as described herein to have a therapeutic effect on the patient.

A system (20) and method (100) using decentralized trace gas sensors (44a, 44b, 44c) and a central control element (46) to detect smoldering material in particulate material processing equipment (26) with continuous air flow (22, 24, 34). First and second sensors (44a, 44c) measure gas concentrations at an air inlet (22) and an air outlet (34), respectively. The control element (46) receives the measurements from the sensors (44a, 44c) simultaneously, considers the first and second concentrations simultaneously to determine an amount of gas being produced in the processing equipment (26), determines whether the amount of gas being produced exceeds a threshold value indicative of smoldering, and if so, activates an alarm. A user interface (48) allows a user to interact with the control element (46), including resetting the alarm, viewing current and stored sensor and system information, and initiating a test of the system by exposing the sensors (44a, 44b, 44c) to gas released from a gas reservoir (50a, 50b, 50c).

A system for wound treatment includes adjunctive wound therapy devices and substrates comprising multiple first reservoirs and multiple second reservoirs. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

A monoplace hyperbaric chamber design to permit at least 2 ATR (about 30 psi relative) internal pressure which accommodates upright seating and, with stiffeners removed for transport, has dimensions to facilitate the chamber passing through a common door opening width of a doctor's examination room where the stiffeners are attached without disturbing a hermetic seal of the hyperbaric chamber.

A system for cooling a hyperbaric chamber includes a compressor, a first hose, a cooling unit, a second hose, and a hyperbaric chamber. The first hose fluidly connects the compressor to the cooling unit, and the second hose fluidly connects the cooling units to the hyperbaric chamber. Compressed air from the compressor travels through a first pressure relief fitting and a second pressure relief fitting, where the compressed air is depressurized according to the system requirements. During the depressurization, the compressed air cools down because of the depressurization and creates a comfortable environment within the hyperbaric chamber.

A portable chamber for hyperbaric and/or hypoxic treatment comprises an open-ended and typically frustro-conical tubular body sized to accommodate at least one occupant, and two end members configured to be respectively received at opposite extremities of the body for closing the body in a seal tight arrangement. The body of the chamber is made of a flexible yet reinforced elastomeric material such as to be collapsible during transport. One of the end members is provided with a door to provide access to the interior of the chamber. The extremities of the body are substantially spherical such as to receive the correspondingly substantially periphery of the end members. When the chamber is supplied with gases during hyperbaric or hypoxic treatment, the spherical peripheries of the end members are urged against the spherical extremities of the body, thereby providing a seal tight chamber. A treatment system comprising the chamber is also disclosed.

A portable hyperbaric chamber with a vertical mounting system includes an inflatable enclosure which is vertically positioned by a rigid base. An internal frame also functions as an additional mounting system so that the inflatable enclosure can be vertically positioned during pressurized and not pressurized instances. A plurality of fill valves allows the inflatable enclosure to be pressurized from externally positioned compressors, and the inside pressure of the inflatable enclosure is measured and displayed through a pressure gauge. The inside pressure can be controlled from a dump valve, a low pressure relief valve, and a high pressure relief valve so that the proper operating pressure can be maintained with the hyperbaric chamber.

A pressured hybrid-construction hyperbaric chamber and method of using same are disclosed. The present invention provides for the fabrication and building of hybrid-construction, solid or semi-flexible wall, exoskeleton reinforced, hybrid hyperbaric chambers suitable for office and/or home use in providing oxygen rich therapies.

A system for wound treatment includes adjunctive wound therapy devices and substrates comprising multiple first reservoirs and multiple second reservoirs. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.

A system (20) and method (100) using decentralized trace gas sensors (44a, 44b, 44c) and a central control element (46) to detect smoldering material in particulate material processing equipment (26) with continuous air flow (22, 24, 34). First and second sensors (44a, 44c) measure gas concentrations at an air inlet (22) and an air outlet (34), respectively. The control element (46) receives the measurements from the sensors (44a, 44c) simultaneously, considers the first and second concentrations simultaneously to determine an amount of gas being produced in the processing equipment (26), determines whether the amount of gas being produced exceeds a threshold value indicative of smoldering, and if so, activates an alarm. A user interface (48) allows a user to interact with the control element (46), including resetting the alarm, viewing current and stored sensor and system information, and initiating a test of the system by exposing the sensors (44a, 44b, 44c) to gas released from a gas reservoir (50a, 50b, 50c).