Disclosed are systems and processes related to cardiopulmonary resuscitation (CPR). One embodiment of the system comprises an inspiration chamber and an expiration chamber, which work cooperatively to provide gas (e.g., Oxygen (O.sub.2)) to a subject (e.g., human patient) during inspiration and extract and expel expired gas (e.g., Carbon Dioxide (CO.sub.2)) from the subject during expiration as a medical professional applies CPR to the subject. In other words, this disclosure provides systems and processes that allow for substantially synchronous chest compressions with positive pressure active inspirations and, also, substantially synchronous chest decompressions with negative pressure active expirations.

A mechanical ventilation system comprises a plurality of ventilation therapy sub-systems. Each of the ventilation therapy sub-systems is adapted to assist a respiratory function of the patient. The system also comprises a detector of the respiratory drive of the patient, an operator interface receiving one or more control parameters, and a main controller. The main controller assigns a therapeutic contribution to each of the ventilation therapy sub-systems based on the respiratory drive of the patient and on the control parameters. The controller modulates the respiratory drive of a patient by controlling each of the plurality of the ventilation therapy sub-systems according to its assigned therapeutic contribution. Distinct ventilation therapy sub-systems may apply negative pressure on the abdomen of the patient, deliver a non-pressurizing inspiratory flow to the patient, or induce a positive pressure in the airways of the patient.

Provided herein are methods of treatment, including methods of treating subjects having or at risk of having or having a viral infection, and specifically a SARS-CoV-2 viral infection. The methods provided include the administration of 4-methylumbelliferone (4-MU), palmitoylethanolamide (PEA), reservatrol, fisetin, H.sub.2, nebulized hyaluronidase or combinations thereof. Also provided herein are a respiratory assistance device, methods of generating a customized respiratory assistance device, methods of treating a coronavirus infection, and methods of inhibiting a coronavirus infectivity, virulence and/or spread.

Methods and devices are provided for manipulating the glymphatic system to improve cognitive and other cranial or brain functions of a subject. In particular, pressure is alternately applied to the jugular veins on either side of the subject's neck to generate a to and fro movement of cranial fluids.

A travel pillow includes a main body, at least one module, and a rotary frame. The main body includes at least one compartment. The at least one module is detachably disposed in the at least one compartment; and the rotary frame is disposed on the outer side of the main body. The rotary frame includes a support arm, a rear support part, and an angle adjustment assembly. The support arm is rotatably connected to the rear support part, and the angle adjustment assembly is disposed between the support arm and the rear support part to adjust an angle between the support arm and the rear support part; and the angle adjustment assembly includes a rotating shaft and a damper rotatably sleeving the rotating shaft. The support arm includes a first socket ring. The rear support part includes a second socket ring.

A mechanical insufflation-exsufflation device including an air source to provide positive airway pressure (PAP); a patient interface; at least one sensor to sense air pressure and flow at the patient interface; and a controller to control the air source to deliver at least one mechanically assisted cough to the patient in response to at least one of a target breathing flow and a target inhalation time period being sensed by the at least one sensor, and when the at least one of a target breathing flow and a target inhalation time period is not sensed, the controller is configured to control the air source to deliver each in a series of high-level PAP provided over a duration being followed by a low-level PAP provided over a duration, the series of high-level PAP increasing in pressure level and duration from a prior one in the series of high-level PAP.

An underwater rescue device, including a cabin provided with a hatch is provided, wherein the hatch is capable to open or close the cabin to form a confined space inside the cabin; a salvage device arranged inside the cabin, comprising a rescue platform and a gripper mechanism arranged on the rescue platform, wherein the rescue platform is movable, the rescue platform is capable to rotate relative to the cabin along at least one rotational axis and is capable to lift and lower to remove the cabin, and the gripper mechanism is configured to grab a drowning person and fix the drowning person on the rescue platform; a cardiopulmonary resuscitation device arranged inside the cabin; a drainage device arranged on the cabin; and a power device arranged on an outer side of the cabin. It has a high degree of automation and can provide immediate rescue for drowning personnel.

A device for cardiopulmonary resuscitation, a pad for assisting with cardiopulmonary resuscitation, and a method for controlling such a device, wherein the parameters of compression depth and frequency of the heart massage, and at least one vital parameter, are continuously monitored, and the parameters of the heart massage within the context of the position of the action of force on the patient's thorax, the direction of the action of force on the patient's thorax, the compression depth and/or the frequency of the heart massage are optimized on the basis of the individual anatomy of the patient.

A system for assisting with a cardiopulmonary resuscitation (CPR) treatment being administered to a patient. In one aspect, the system includes electrodes to provide an ECG signal of the patient, one or more sensors configured to measure an intrinsic myocardial wall movement of the patient, and one or more processors. The one or more processors are configured to perform operations including: during the CPR treatment being administered to the patient, receiving an input from the sensor(s), processing the input from the sensor(s) and the ECG signal, determining, based on processing, whether the intrinsic myocardial wall movement is indicative of a perfusion movement of the patient's heart, and providing an indication to a user of the system based on the determination.

A flow sensor system for ventilation treatment comprises a flow conduit configured to allow gas flow between a first region and a second region, the flow conduit defining a lumen for the gas flow; a flow restrictor disposed within the lumen of the flow conduit between the first region and the second region; a first absolute pressure sensor disposed adjacent to the first region of the flow conduit and configured to measure a pressure of the gas flow at the first region of the flow conduit; and a second absolute pressure sensor disposed adjacent to the second region of the flow conduit and configured to measure pressure of the gas flow at the second region of the flow conduit.