An alignment device for assisting a rescuer for correctly aligning a mechanical cardiopulmonary resuscitation (CPR) device. The alignment device can guide positioning of the backboard so that the backboard is correctly positioned prior to connecting an upper portion of the mechanical CPR device to the backboard. The alignment device can also include positioning the mechanical CPR device without a backboard or positioning the backboard and the upper portion of the mechanical CPR device nearly simultaneously.

A method for providing information to a user, preferably including: determining environmental information; determining a set of features based on the information; determining output parameters based on the features; and controlling a sensory output system to generate outputs based on the output parameters. A sensory output device, preferably including a plurality of sensory output actuators. A system for providing information to a user, preferably including one or more: sensory output devices, sensors, and computing systems.

A method for cardiopulmonary resuscitation (CPR) includes supplying an inflation gas at an operative pressure to an inflation actuated soft gripper device to change form from an undeployed state to a deployed grip state that accommodates and grips a human torso. The inflation actuated soft gripper device includes a first inflatable gripper arm having a first distal end and a second inflatable gripper arm having a second distal end. The first distal end and the second distal end approach one another from the undeployed state to the deployed grip state. The first and second distal ends are spaced apart from one another further in the undeployed state than in the deployed grip state. An actuator power and a CPR control signal are delivered to a CPR pressure application device to cyclically extend and retract a pressure applicator along an axis in alignment with a sternum of the human torso.

An improvement to portable cardiopulmonary resuscitation (CPR), includes a first module hub housing, an inflation actuated soft gripper configured to receive an inflation gas in response, to change form to a deployed grip state that accommodates and grips a human torso. Improvements include the inflatable gripper not requiring lifting the patient. Improvements also include modularity for in-the-field reconfigurability, in which a second module hub housing attaches to the first module hub housing, carrying a CPR pressure applicator configured to receive an actuator power and control signal causing, concurrent with the deployed grip state, cyclic extension and retraction of a pressure applicator along an axis aligned with a sternum of the human torso.

The present disclosure relates to extracellular vesicles (EVs) that are capable of targeting a cell in the CNS of a subject. Also provided herein are methods for producing the EVs and methods for using the EVs to treat and/or prevent diseases or disorders of the CNS (e.g., neurological disorders).

The present invention provides, among other things, apparatus and methods of use for treating a subject in need of assistance with breathing. In some embodiments the subject suffers from airflow obstruction. In some embodiments, the subject suffers from chronic obstructive pulmonary disease.

The present invention relates to an automated stimulation device for inducing a tactile inter-stimulus onset asynchrony (ISOA) effect in a subject suffering from apnea, bradycardia and/or hypoxia, the device comprising at least two actuators configured for contacting a body portion of the subject, and interspaced for producing an apparent tactile movement in the subject upon sequential induction of actuation, wherein the duration of the actuations and the overlap in actuation time between the at least two actuators is controlled to attain an inter stimulus onset asynchrony (ISOA).

There is provided a dynamic and proactive system for supporting sitting while detecting and changing sitting postures of a user and method of operation thereof. The system including a frame, a plurality of supports, each configured to support a different body part, and a plurality of joints each configured to move independently of or together with any other of the joints, each of the supports is connected to the frame via a corresponding joint, at least one of the joints is a two dimensional joint which enables a change in angle between the frame and a corresponding support. Each one of the plurality of supports is configured to move with respect to the frame or to another support, thereby enabling any changes in sitting postures of the user. The system comprises sensors, which based on their readings, the system detects user postures and suggests or creates posture changes.

A percussion apparatus for sputum clearance includes a percussion unit, a drive unit, and a control unit, the percussion unit includes a percussion member and an angle detector, the angle detector is configured to detect an included angle between the reference plane and a horizontal plane, the control unit is electrically connected with the drive unit, and when the included angle conforms to a preset angle, the control unit controls the drive unit to drive the percussion unit to periodically percuss, which greatly saves the manpower and increase the efficiency of sputum clearance.

Compression garment systems and methods may deliver fluid to one or more fluid cells using a target pressure and an adjustable manifold pressure that may be adjusted to, for example, deliver an amount of fluid to the one or more fluid cells to achieve the desired target pressure. Further, the compression garment systems and methods may provide a graphical user interface depicting a human-shaped graphical element and a compression therapy graphical indication about the human-shaped graphical element. The compression therapy graphical indication may indicate, or show, where on the human-shaped graphical element the compression therapy may be delivered to. Still further, the compression garment systems and methods may include or use a communication interface to determine or identify a compression garment to be used therewith. The identity of the compression garment can be used to configure compression therapy for the compression garment.