Disclosed are a method and a device for transferring a nanoparticle monolayer by using a capillary tube, wherein a nanoparticle monolayer present in a liquid-gas interface is locally and selectively separated and then transferred to a substrate by using a capillary tube. Accordingly, nondestructive and reproducible transfer can be made regardless of the surficial properties and structures of the substrate to which the monolayer is to be transferred. Therefore, the method and the device enable an in-situ high-speed inspection of harmful materials, such as an illegal drug and a residual pesticide, on surfaces of various solids such as fiber clothes, food and banknotes, and can be easily coupled to a microfluid channel having a small size and a complicated structure. Further, the method and the device can transfer a nanoparticle monolayer in a simple and inexpensive process without using special and expensive equipment.

A lacrimal tear flow measurement device, and methods of manufacture and use, are described that includes a polymer microcapillary tube or similar structure having at least one end coated on the outside with soft silicone rubber and one end treated on the inside to be hydrophobic. The hydrophobic end keeps liquid from escaping or entering that end while allowing air to pass. The rest of the tube's insides may be hydrophilic or a neutral hydrophobe. As a Schirmer's test strip replacement, the entrance end of the device can be touched to the lacrimal lake of a patient's eye to collect suck up, or merely collect, tear fluid within the collection tube for weighing, volume measurement, or other analysis. Long-term collection devices for wear between doctors' visits can have a bypass channel allowing liquid to flow back onto the eye.

A contact lens according to an embodiment of the present disclosure includes a lens section attachable to an eyeball, and one or a plurality of structure portions provided in the lens section and intended to accumulate tears. This makes it possible to, for example, measure an absorption spectrum of the tears, by emitting light toward the tears accumulated in the one or plurality of structure portions.

A liquid transfer line receives a liquid having particles suspended therein and transfers the liquid to a capillary tube. A support tube secures the capillary tube therein. The support tube is substantially airtight except at a designated position. An optional securement secures the capillary tube within the support tube. A discharge end of the capillary tube is spaced from, and receded into, a discharge end of the support tube. A chuck is positioned below the support tube and is operable to open and to close to seal the designated position of the support tube. A sample substrate filters the liquid introduced through the liquid transfer line. Yet further, the sample preparation system comprises a pump that draws a vacuum that exhausts portions of the liquid that are not retained on the sample substrate.

A liquid transfer line receives a liquid having particles suspended therein and transfers the liquid to a capillary tube. A support tube secures the capillary tube therein. The support tube is substantially airtight except at a designated position. An optional securement secures the capillary tube within the support tube. A discharge end of the capillary tube is spaced from, and receded into, a discharge end of the support tube. A chuck is positioned below the support tube and is operable to open and to close to seal the designated position of the support tube. A sample substrate filters the liquid introduced through the liquid transfer line. Yet further, the sample preparation system comprises a pump that draws a vacuum that exhausts portions of the liquid that are not retained on the sample substrate.

A capillary tube holder is provided for holding a capillary tube. The capillary tube holder includes a holder insert and a holder base. The holder insert includes a capillary groove configured for receiving the capillary tube. The holder base is configured for slidably receiving and retaining the holder insert therein.

Various embodiments are directed to a fluid sampling cartridge for capturing a fluid sample and methods of using the same. In various embodiments, a fluid sampling cartridge comprises a fluid conduit having an interior conduit portion, wherein the fluid conduit is configured to receive a volume of fluid at a fluid conduit inlet such that the fluid conduit defines a fluid flow path within the interior conduit portion; a capillary component having a first capillary end in fluid communication with the interior conduit portion and configured to receive at least a portion of the volume of fluid to define a fluid sample; and a cartridge housing defining an interior housing portion, wherein the cartridge housing is configured for engagement with the fluid conduit and the capillary component such that at least a portion of each of the fluid conduit and the capillary component is disposed within the interior housing portion.

Disclosed are methods for evaluating a value of probability of monoclonality of populations of cells.

A protective cover is for use with a measurement device. The measurement device is provided with an insertion aperture for insertion of a test strip onto which a liquid sample is spotted. The protective cover is inflected such that a rear face side thereof is recessed to match the shape of an end portion of the measurement device at which the insertion aperture is disposed. The protective cover is provided with an opening portion at which the test strip is insertable. A first drawing portion is provided at a rear face side lower edge of the opening portion. The first drawing portion draws the liquid sample by capillary force.

A system includes a capillary having a first end connected to a sampling device and a second end. The sampling device is configured to separate a sample with a separation solution and deliver the sample and the separation solution to the second end. The second end is coupled to a capillary ground contact. A transport liquid supply system in fluidic communication with a transport liquid supply conduit provides a transport liquid from a transport liquid source through the transport liquid supply conduit. The transport liquid provided from the transport liquid supply conduit includes a receiving volume defined at least in part by a meniscus. The second end of the capillary is in fluidic communication with the receiving volume. A liquid exhaust system in fluidic communication with a removal conduit removes liquid from the receiving volume. An analysis system is in fluidic communication with the removal conduit.