G01N2015/1443

Imaging flow cytometer
12270749 · 2025-04-08 · ·

An imaging flow cytometer includes: a flow channel in which an observation object flows and a length in a width direction is longer than a length in a height direction; an acoustic element configured to apply acoustic waves as standing waves to the flow channel; a light source that irradiates the flow channel with illumination light; an image sensor configured to image at least a line included in a cross section of the observation object crossing a flow line direction which is a direction in which the observation object flows in the flow channel by measuring or imaging the observation object passing through a position irradiated with the illumination light; and circuitry configured to generate an image in which the observation object is scanned in the flow line direction on the basis of a plurality of captured images acquired by the imaging unit imaging the line in a time series.

SCANNING INFRARED MEASUREMENT SYSTEM
20170016813 · 2017-01-19 ·

An analyzer of a component in a sample fluid includes an optical source and an optical detector defining a beam path of a beam, wherein the optical source emits the beam and the optical detector measures the beam after partial absorption by the sample fluid, a fluid flow cell disposed on the beam path defining an interrogation region in the a fluid flow cell in which the optical beam interacts with the sample fluid and a reference fluid; and wherein the sample fluid and the reference fluid are in laminar flow, and a scanning system that scans the beam relative to the laminar flow within the fluid flow cell, wherein the scanning system scans the beam relative to both the sample fluid and the reference fluid.

Determining one or more proportional particle group shares in flue gas of a recovery boiler
12298004 · 2025-05-13 · ·

A method and system to determine one or more proportional particle group shares in flue gas of a recovery boiler (110) based on optical information gained from a flue gas sample. A processor (202) is used to read (301) a digital frame comprising the area under consideration, which represents at least a part of the surface of a sampler (120) kept in the flue gas flow of a recovery boiler. Particle group areas matching a color characteristic of the particle group comprised in the flue gas is determined (302) from the area under consideration. The joint area of the identified particle group areas is determined (304), and the share of the joint area from the total area is determined (305) as the proportional particle group share of the particle group.

Systems and methods for improved imaging and fluorescence in flow cytometry and other applications

Provided are systems and methods that allow for brightfield imaging in a flow cytometer, allowing for collection of fluorescence and high-quality image date. The disclosed technology also gives rise to an illumination pattern that allows a user to create different oblique or structured illumination profiles within a static system. With the disclosed approach, a user can illuminate a sample from a first direction (e.g., with laser illumination configured to give rise to one or more of fluorescence information and scattering information), collect scattering information from a second direction, collect fluorescence information from a third direction, and capture an image of the sample from a fourth direction. (Two or more of the foregoing can be accomplished simultaneously.) Also as described elsewhere herein, an illumination used to illuminate the sample for visual image capture can be communicated to the same through a lens that also collects fluorescence from the sample.

CELL ANALYSIS METHOD AND CELL ANALYSIS SYSTEM

A cell analysis method and a cell analysis system are provided. The cell analysis method includes: providing a flow unit to provide a path in which a cell flows, the flow unit including a light emitting layer to, in response to being irradiated by a first light in a first wavelength band, emit a second light in a second wavelength band; irradiating the light emitting layer with the first light; emitting the second light from the light emitting layer in response to the irradiation of the first light; acquiring an image formed by reacting the cell with the second light emitted from the light emitting layer; and analyzing the cell from the acquired image.

Method for automatically examining a liquid sample
12504358 · 2025-12-23 · ·

The invention relates to a method for automatically examining a liquid sample, which has a liquid and at least one particle, by means of a first measurement signal which emanates from a liquid region and which serves to determine at least one particle with a first property, and by means of a second measurement signal which emanates from the liquid region and serves to determine at least one particle with a second property, the first measurement signal and the second measurement signal being evaluated independently of one another and whether a particle condition has been satisfied in the liquid region subsequently being determined on the basis of the evaluated first measurement signal and the evaluated second measurement signal.

Detection optical system, detection device, flow cytometer, and imaging cytometer

A detection optical system includes an objective lens, a first relay lens, a second relay lens, and an imaging lens, which are arranged in order from a side of a specimen along an optical path of light from the specimen illuminated by a light source. A primary imaging plane is provided on the optical path between the first relay lens and the second relay lens. An aspherical correction plate that corrects spherical aberration is arranged at a position located between the second relay lens and the imaging lens and substantially conjugate with a pupil position of the objective lens.