An optical signal detection module includes an optical measurement device (OMD) configured to detect an optical emission signal from an emission signal source placed in a signal-detecting position of the OMD. The optical signal detection module also includes a cover moveable between a closed position covering the signal-detecting position and an open position not covering the signal-detecting position. The cover includes an optical reference material that emits a reference emission detectable by the OMD. The cover is configured so that, when the cover is in the closed position, the inner surface is in the signal-detecting position of the OMD so that the OMD detects the reference emission. The optical signal detection module can also include a drive assembly coupled to the cover and configured to move the cover between the open position and the closed position. In some embodiments, the OMD can include a fluorometer.

The invention relates to a method and to an assembly for calibrating devices 11 for detecting blood or blood components in a liquid, in particular dialysate, which devices comprise a light transmitter 17 and a light receiver 18, and an evaluation unit 20 that receives the signal from the light receiver 18 and is designed such that blood or blood components in the liquid are detected on the basis of the weakening of radiation passing through the liquid. The method according to the invention is based on the fact that the calibration of the devices 11 for detecting blood or blood components is carried out without the use of blood. The calibration is carried out using an absorption standard 30, which has predetermined optical properties in relation to the absorption of the light in blood, the absorption standard 30 being arranged in the beam path 19 between the light transmitter 17 and the light receiver 18. The absorption standard 30 makes it possible to identify defined spectral weakening in the light depending on the components of the blood, in particular haemoglobin. Since, by contrast with blood, the absorption standard 30 does not bring about any scattering, meaning that the beam path is influenced in a different way from blood, the calibration is also carried out using a scattering standard 36, which has predetermined optical properties in relation to the scattering of the light in blood. The assembly also comprises a beam deflection unit 22 for coupling out light for a spectral measurement of the light transmitter 17 using a spectrometer 27.

Sensor and Measurement Method A turbidity sensor and method of measuring turbidity is provided. The turbidity sensor (100) comprises first and second optical detectors for detecting a respective optical response of each optical signal. The first optical detector (20) may be arranged in direct view of the emitter (10) and the second optical detector (30) may be arranged in indirect view of the emitter (10). The two detectors collect light emitted from the emitter (10) when directed through a fluid sample during two optical tests run in very close succession. Firstly, a control sample is illuminated to determine a calibration factor for the control sample with known turbidity. Then, the calibration factor is used to determine the turbidity of a fluid sample with unknown turbidity. Advantageously, background radiation during the data collection process is ignored because the transient behaviour during each optical test is negligible. The approach is more convenient over known turbidity sensors and measurement methods, particularly in light of the calibration step.

A device for measuring a reflectivity of an object at the seabottom, includes a spectral probe, a first white board, a second white board, a distance meter, and a shaft; the first white board and the second white board respectively have a known reflectivity; the first white board and the second white board are connected to the shaft, wherein the first white board and the second white board are spaced along an axial direction of the shaft and staggered from each other along a radial direction of the shaft; the spectral probe is configured to collect spectral data of the first white board, the second white board and the object at the seabottom; the distance meter is configured to collect distance data between the spectral probe and the object at the seabottom.

The present disclosure relates to a system for process-integrated optical analysis of flowable media, comprising a processing system for processing a flowable medium and an analytical system for analysis of the flowable medium, wherein the analytical system includes an optical measuring head, for irradiation of the medium and for receiving measuring radiation, and a reference unit. The processing system includes a measuring region, into which the medium can be introduced during the processing and which is accessible for measurement by means of the measuring head. According to the invention, a mechanism for achieving defined positions of the measuring head relative to the measuring region and/or relative to a reference unit is included, which selectively enables a measurement of the medium located in the measuring region or of the reference unit.

A method of obtaining a quantum efficiency distribution in a predetermined sample surface, including: irradiating a reference material with excitation light belonging to a first wavelength range; obtaining the reference material's image, which includes a first channel for the first wavelength range and a second channel for a second wavelength range, the first and the second channel's irradiation luminance value in each pixel; irradiating the predetermined sample surface with the excitation light; obtaining the first and the second channel's measurement luminance value in each pixel of the image of the predetermined surface; calculating an absorption luminance value from a difference between the first channel's irradiation luminance value and measurement luminance value; calculating a fluorescence luminance value from difference between the second channel's irradiation luminance value and measurement luminance value; calculating quantum efficiency of each pixel based on the values; and obtaining quantum efficiency distribution.

This relates to systems and methods for measuring a concentration and type of substance in a sample at a sampling interface. The systems can include a light source, optics, one or more modulators, a reference, a detector, and a controller. The systems and methods disclosed can be capable of accounting for drift originating from the light source, one or more optics, and the detector by sharing one or more components between different measurement light paths. Additionally, the systems can be capable of differentiating between different types of drift and eliminating erroneous measurements due to stray light with the placement of one or more modulators between the light source and the sample or reference. Furthermore, the systems can be capable of detecting the substance along various locations and depths within the sample by mapping a detector pixel and a microoptics to the location and depth in the sample.

By way of overview and introduction, various embodiments of the apparatus, systems and methods described herein are directed improved approaches to aligning and standardizing different total spectral radiance factor shapes measured with different instruments. Furthermore, in one or more configurations and approaches, the disclosure presented herein is directed to obtaining a whiteness calibration value for use in sample measurements without the need of UV filter adjustments.

According to an embodiment, a paper sheet processing device includes a fluorescence reference member, a light source, and a sensor. The fluorescence reference member is configured to demonstrate fluorescence in accordance with an intensity of excitation light applied. The light source configured to apply the excitation light to the fluorescence reference member and a paper sheet. The sensor configured to take, at a plurality of sensitivity wavelengths, images of irradiation surfaces of the fluorescence reference member and the paper sheet being irradiated with the excitation light. The fluorescence reference member includes a transmittance control element for the excitation light.

Method for wide range gas detection using a gas detection system comprising a sample gas inlet, a reference gas inlet, a gas modulation valve and a gas analyzer, wherein the gas modulation valve alternatingly connects the sample gas inlet to the gas analyzer during a sample gas time period and the reference gas inlet to the gas analyzer during a reference gas time period, characterized in that the sample gas time period is shorter than the reference gas time period such that the sample gas concentration in the gas analyzer is reduced.