Apparatus and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above overtime. Embodiments of the invention are particularly useful in surgery, clinical procedures, tissue assessment, diagnostic procedures, health monitoring, and medical evaluations, especially in the detection and treatment of cancer.

Systems, apparatuses and methods for rapidly evaluating light transmission through coatings including paints, primers, thin films, surfacing films, laminates and the like are disclosed. The system includes a light source for transmitting light through a coating sample. A sample holder holds the coating sample in a position to receive the incident light. A spectrometer measures an amount of the transmitted light that passes through the coating sample. Optionally, one or more optical filters may be used to condition any transmitted light that passes through the coating sample to reduce the intensity of the light outside of wavelengths of interest. An opaque cover encloses the spectrometer, the one or more optional optical filters, and at least part of the sample holder to prevent light other than the transmitted light from the light source from entering the spectrometer such that any transmitted light passing through the coating sample can be accurately evaluated.

This N.sub.2O analysis device is provided with: a light source (11) which radiates laser light onto an exhaust gas (5) containing N.sub.2O, H.sub.2O and CO.sub.2; a light receiver (13) which receives the laser light that has been radiated onto the exhaust gas (5); a light source control unit (14a) of a control device (14), which controls the wavelength of the laser light radiated by the light source (11) to between 3.84 m and 4.00 m; and a signal analyzing unit (14b) of the control device (14), which calculates the N.sub.2O concentration by means of infrared spectroscopy, using the laser light received by the light receiver (13) and the laser light controlled by the light source control unit (14a) of the control device (14).

A device for determining the composition of a mixture of fluids by spectral absorption, comprises: a radiation source; a detector for detecting radiation that has been attenuated by the mixture; and a device for separating the radiation into a wavelength band corresponding to an absorption band of one of the fluids, a wavelength band corresponding to an absorption band of another of the fluids, and at least one reference wavelength band substantially adjacent to each of the absorption bands, and especially adjacent to each side of the absorption band or group of absorption bands. The device may be used to determine the composition of mixtures of oil, water and gaseous hydrocarbons in oil wells where there is a very large degree of time varying scattering e.g. Rayleigh and Mie scattering due to turbulence.

Methods and systems for performing spectroscopic reflectometry measurements of semiconductor structures at infrared wavelengths are presented herein. In some embodiments measurement wavelengths spanning a range from 750 nanometers to 2,600 nanometers, or greater, are employed. In one aspect, reflectometry measurements are performed at oblique angles to reduce the influence of backside reflections on measurement results. In another aspect, a broad range of infrared wavelengths are detected by a detector that includes multiple photosensitive areas having different sensitivity characteristics. Collected light is linearly dispersed across the surface of the detector according to wavelength. Each different photosensitive area is arranged on the detector to sense a different range of incident wavelengths. In this manner, a broad range of wavelengths are detected with high signal to noise ratio by a single detector.

A device analyzes an anesthesia ventilation gas with an infrared radiation source and includes a gas cuvette, a Fabry-Perot interferometer with a band pass filter function, adjustable with respect to a central transmission wavelength as a function of a control signal, a detector providing a measured signal and a computing and control unit providing the control signal and detecting the measured signal. The computing and control unit is configured to actuate the Fabry-Perot interferometer in a first operating mode by the control signal such that the central transmission wavelength scans a predefined wavelength range, to detect a presence in the ventilation gas sample potential types of anesthetic gases based on the measured signal. In a second operating mode, the control unit controls the central transmission wavelength within a subrange of the predefined wavelength range and determines a plurality of concentration values at consecutive times for detected types of anesthetic gases.

A device analyzes an anesthesia ventilation gas with an infrared radiation source and includes a gas cuvette, a Fabry-Perot interferometer with a band pass filter function, adjustable with respect to a central transmission wavelength as a function of a control signal, a detector providing a measured signal and a computing and control unit providing the control signal and detecting the measured signal. The computing and control unit is configured to actuate the Fabry-Perot interferometer in a first operating mode by the control signal such that the central transmission wavelength scans a predefined wavelength range, to detect a presence in the ventilation gas sample potential types of anesthetic gases based on the measured signal. In a second operating mode, the control unit controls the central transmission wavelength within a subrange of the predefined wavelength range and determines a plurality of concentration values at consecutive times for detected types of anesthetic gases.

Methods and assemblies may be used for determining and using standardized spectral responses for calibration of spectroscopic analyzers. The methods and assemblies may be used to calibrate or recalibrate a spectroscopic analyzer when the spectroscopic analyzer changes from a first state to a second state, the second state being defined as a period of time after a change to the spectroscopic analyzer causing a need to calibrate or recalibrate the spectroscopic analyzer. The calibration or recalibration may result in the spectroscopic analyzer outputting a standardized spectrum, such that the spectroscopic analyzer outputs a corrected material spectrum for an analyzed material, and defining the standardized spectrum. The corrected material spectrum may include signals indicative of material properties of an analyzed material, the material properties of the material being substantially consistent with material properties of the material output by the spectroscopic analyzer in the first state.

An optical device for detecting a first chemical species and a second chemical species contained in a specimen, which includes: a first optical sensor, which may be optically coupled to an optical source through the specimen and is sensitive to radiation having a wavelength comprised in a first range of wavelengths; and a second optical sensor, which may be optically coupled to the optical source through the specimen and is sensitive to radiation having a wavelength comprised in a second range of wavelengths, different from the first range of wavelengths.

Apparatuses and methods are disclosed for performing a light-absorption measurement on a test sample and a compliance measurement on a reference sample. A method includes moving a reference sample receptacle carrier of an apparatus to position a first reference sample receptacle received in the carrier at a second position in a light path, directing light from an illumination system to a detection system along the light path to perform a light-absorption measurement on a first reference sample at the second position, moving the carrier to position the first receptacle out of the light path, placing a test sample receptacle in a test sample receptacle holder of the apparatus in the light path at a first position different from the second position, and directing light along the light path to perform a light-absorption measurement on a test sample in the test sample receptacle holder at the first position.