An approach to noninvasively and remotely detect the presence, location, and/or quantity of a target substance in a scene via a spectral imaging system comprising a spectral filter array and image capture array. For a chosen target substance, a spectral filter array is provided that is sensitive to selected wavelengths characterizing the electromagnetic spectrum of the target substance. Elements of the image capture array are optically aligned with elements of the spectral filter array to simultaneously capture spectrally filtered images. These filtered images identify the spectrum of the target substance. Program instructions analyze the acquired images to compute information about the target substance throughout the scene. A color-coded output image may be displayed on a smartphone or computing device to indicate spatial and quantitative information about the detected target substance. The system desirably includes a library of interchangeable spectral filter arrays, each sensitive to one or more target substances.

A system and method are disclosed for configuring an integrated computational element (ICE) to measure a property of a sample of interest. The system includes an illumination source to provide a sample light which is reflected from or transmitted through a sample. A dispersive element disperses the sample light into wavelength portions. An intensity modulation device having an array of electronically controllable modulation elements is disclosed that forms a pattern which modulates the dispersed sample light. Collection optics focuses the modulated sample light on a detector, which generates a signal that correlates to a property of the sample. The electronically controllable modulation elements can be readily altered to conform to a different measurable property of a sample of interest as desired.

An embodiment of the present disclosure provides a spectrum inspecting apparatus. The apparatus includes a laser source; a focusing cylindrical lens configured to converge a light beam onto a sample; a light beam collecting device configured to collect a light beam signal, which is excited by the light beam, from the sample, so as to form a strip-shaped light spot; a slit configured to receive the collected light beam and couple it to downstream of a light path; a collimating device; a dispersing device configured to disperse the collected light beam so as to form a plurality of sub-beams having different wavelengths; an imaging device configured to image the sub-beams on the photon detector array respectively, wherein the light beam emitted from the laser source has a rectangular cross-section, the strip-shaped light spot impinges on the slit and its length is smaller than a length of the slit.

The present disclosure relates to a device for measuring an optical absorption property of a fluid as function of wavelength. The device comprises a broadband light source for emitting light, a plurality of integrated optical waveguides for guiding this light, and a light coupler for coupling the emitted light into the integrated optical waveguides such that the light coupled into each integrated optical waveguide has substantially the same spectral distribution. The device also comprises a microfluidic channel for containing the fluid, arranged such as to allow an interaction of the light propagating through each waveguide with the fluid in the microfluidic channel. Each integrated optical waveguide comprises an optical resonator for filtering the light guided by the waveguide according to a predetermined spectral component. The spectral component corresponding to each waveguide is substantially different from the spectral component corresponding to another of the waveguides.

An approach to noninvasively and remotely detect the presence, location, and/or quantity of a target substance in a scene via a spectral imaging system comprising a spectral filter array and image capture array. For a chosen target substance, a spectral filter array is provided that is sensitive to selected wavelengths characterizing the electromagnetic spectrum of the target substance. Elements of the image capture array are optically aligned with elements of the spectral filter array to simultaneously capture spectrally filtered images. These filtered images identify the spectrum of the target substance. Program instructions analyze the acquired images to compute information about the target substance throughout the scene. A color-coded output image may be displayed on a smartphone or computing device to indicate spatial and quantitative information about the detected target substance. The system desirably includes a library of interchangeable spectral filter arrays, each sensitive to one or more target substances.

A purpose of the present invention is to provide an optical measurement system or the like suitable for optical measurement of nucleic acids, proteins, etc.

In a first aspect of the present invention, an optical measurement system that provides optical sample measurement comprises: an optical cell having a sample-holding hollow portion; and a light source unit that emits broadband light containing first and second light to the optical cell. The optical cell includes: a first light guide where light passes through a first transparent portion that transmits the first light more readily than the second light and the hollow portion without passing through a second transparent portion that transmits the second light more readily than the first light; and a second light guide that differs from the first light guide, in which light passes through the second transparent portion and the hollow portion without passing through the first transparent portion.

An optical device for detecting a first chemical species and a second chemical species contained in a specimen, which includes: a first optical sensor, which may be optically coupled to an optical source through the specimen and is sensitive to radiation having a wavelength comprised in a first range of wavelengths; and a second optical sensor, which may be optically coupled to the optical source through the specimen and is sensitive to radiation having a wavelength comprised in a second range of wavelengths, different from the first range of wavelengths.

The present disclosure describes a device for measuring an optical absorption property of a fluid as function of wavelength. The device comprises a broadband light source for emitting light, a plurality of integrated optical waveguides for guiding this light and a light coupler for coupling the emitted light into the integrated optical waveguides such that the light coupled into each integrated optical waveguide has substantially the same spectral distribution. The device also comprises a microfluidic channel for containing the fluid, arranged such as to allow an interaction of the light propagating through each waveguide with the fluid in the microfluidic channel, and a plurality of spectral analysis devices optically coupled to corresponding waveguidessuch as to receive the light after interaction with the fluid. The spectral analysis devices are adapted for generating a signal representative of a plurality of spectral components of the light.

A portable device for detecting and/or quantifying hemozoin by optical reflectance spectrophotometry, directly on the patient's skin, on tissues or in a liquid sample which comprises means for calibrating the device; at least one optical emitter to excite the sample; at least eight optical detectors to detect the reflectance spectrum of the sample; at least eight bandpass optical filters to filter the reflected light for each optical detector; wherein the optical filters and optical detectors are aligned with each other, wherein the emitter and optical detectors are positioned allowing reflection of the emitted light towards the optical detectors, wherein the optical filters and optical detectors comprise wavelengths between 400 nm and 800 nm; and a microcontroller configured to calculate a ratio between the reflectance values of the sample at each wavelength to detect the reflectance peaks. Also disclosed is a method of detecting and/or quantifying hemozoin by optical reflectance spectrophotometry.

A food processing device or food storage device (70), having: a chamber (72) for housing a foodstuff (42) to be processed or stored; and a nutrition/ingredient analysis system (30), having: an electromagnetic radiation source (32); a radiation guide (34) for guiding the electromagnetic radiation based on total internal reflection (attenuated total reflection, ATR), wherein the radiation guide comprises an input (36) coupled to the electromagnetic radiation source (32), an output (38), and a sensing surface (40) between the input and output for placing against a foodstuff to be analyzed, wherein the sensing surface (40) is for contact with the foodstuff (42); a detector (44) for detecting guided electromagnetic radiation at the output of the radiation guide; and a filter arrangement (46) for wavelength filtering the guided electromagnetic radiation reaching the detector, wherein the filter arrangement includes a plurality of optical bandpass filters (46a, 46b), and the plurality of filters are selectively movable into the path of the detector (44) or there is a respective detector (44a, 44b) for each optical bandpass filter.