A chip-scale integrated multi-wavelength biological sensing device employing a plurality of filter-sensor assemblies is provided. The plurality of filter-sensor assemblies can include sufficient number of optical channels enabled by plasmonic filters having different nanoscale patterns and provided directly on an array of photodetectors. Combined with simultaneous illumination of light including multiple peak wavelengths with small full width at half maximum values, the independent optical channels of the plurality of filter-sensor assemblies enable correlation of detected optical signals with biological parameters. Signal processing methods for robustly extracting The PPG signals can be extracted by a robust signal processing method. Successful measurement of peripheral blood oxygen (SpO.sub.2) and blood pressure has been demonstrated.

A device for measuring oxygen saturation includes circuitry configured to measure a first diode voltage at a light emitting diode while applying a first current through the light emitting diode, measure a second diode voltage at the light emitting diode while applying a second current through the light emitting diode, and measure a third diode voltage at a light emitting diode while applying a third current through the light emitting diode. The circuitry is further configured to determine a series resistance based on the first diode voltage, the second diode voltage, and the third diode voltage and determine an intensity of a received photonic signal corresponding to an output photonic signal output using the light emitting diode. The circuitry is further configured to determine an oxygen saturation level based on the intensity of the received photonic signal and the series resistance.

An analysis device includes a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, an image sensor that includes a RGB color filter, and a signal processing unit. In this configuration, the first special light includes light in a first wavelength region and the second special light includes light in a second wavelength region that is different from the first wavelength region. The signal processing unit calculates an indicator that indicates a feature amount of biological tissue based on a pixel signal that corresponds to the light in the first wavelength region and a pixel signal that corresponds to the light in the second wavelength region, and generates a color captured image based on a pixel signal that corresponds to light that passes through the RGB color filter.

A breath analyte capture device includes a breath input port into which a user exhales a breath sample, and a cartridge insertion port for receiving a disposable cartridge containing an interactant. During exhalation of a breath sample, at least a portion of the breath sample is routed through the cartridge such that the analyte (such as breath acetone) is captured by the interactant. In some embodiments, the concentration of the analyte in the breath sample is measured by monitoring a chemical reaction that occurs in the disposable cartridge. The chemical reaction may be monitored by illuminating the cartridge at each of multiple light wavelengths while measuring reflected light.

A plurality of color sensing sections are attached to a toilet seat so as to test a health state or a fecal occult blood portion every time by capturing the feces surface color during defecation. Before feces which have been excreted from a body sink into a water-seal portion, the circumference of the feces is optically captured to detect the color of the surface of the feces. By monitoring changes in color, the health state of the defecator is monitored. In particular, by checking the presence/absence of an occult blood portion, the present invention assists in early detection of colorectal cancer and allows a fecal occult blood test to be performed in a hygienic manner without burdening the user.

A plurality of color sensing sections are attached to a toilet seat so as to test a health state or a fecal occult blood portion every time by capturing the feces surface color during defecation. Before feces which have been excreted from a body sink into a water-seal portion, the circumference of the feces is optically captured to detect the color of the surface of the feces. By monitoring changes in color, the health state of the defecator is monitored. In particular, by checking the presence/absence of an occult blood portion, the present invention assists in early detection of colorectal cancer and allows a fecal occult blood test to be performed in a hygienic manner without burdening the user.

Systems, methods and apparatus for determining an amount of blood in a blood culture are provided where an initial biological state and then periodic measurements of the biological state of the culture are taken. For each respective measurement, a normalization relative value between the respective measurement and the initial measurement is made thereby forming normalization relative values. For each interval of time points represented by the normalization relative values, a first derivative of the normalization relative values in the interval is made thereby forming a plurality of rate transformation values. For each set of rate transformation values in the plurality of rate transformation values, an average relative transformation value is computed, thereby forming average relative transformation values. A lookup table that matches a measure of central tendency of the average relative transformation values to a blood amount is used to determine the amount of blood in the culture.

A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, and a CPU determining temporal relative change amounts of oxygenated hemoglobin concentration and deoxygenated hemoglobin concentration and determining a correlation coefficient of the relative change amounts and a polarity of a slope of a regression line.

An oximeter sensor system includes a light source group having a plurality of LEDs including at least a first visible light LED, a second visible light LED and an infrared LED adjacent the first visible light LED and the second visible light LED, an infrared filter disposed in front of only the first visible light LED and the second visible light LED, a light source housing having a base, one or more sidewalls and a light-emitting end where the light source housing has a frustum shape where the light source group is disposed adjacent the base and facing the light-emitting end and where the one or more sidewalls has a reflective coating thereon, a light detector disposed opposite to, spaced from and facing the light-emitting end of the light source housing, and a cuvette disposed between the light-emitting end of the light source housing and the light detector.

An analysis device includes a wavelength selection unit that alternatively extracts first special light and second special light from light emitted from the light source device, an image sensor that includes a RGB color filter, and a signal processing unit. In this configuration, the first special light includes light in a first wavelength region and the second special light includes light in a second wavelength region that is different from the first wavelength region. The signal processing unit calculates an indicator that indicates a feature amount of biological tissue based on a pixel signal that corresponds to the light in the first wavelength region and a pixel signal that corresponds to the light in the second wavelength region, and generates a color captured image based on a pixel signal that corresponds to light that passes through the RGB color filter.