A device for light-based analysis of a substance in a liquid sample comprises: an analysis cell for holding the liquid sample during analysis; a plunger configured for movement along walls of the analysis cell for allowing entry of the liquid sample into the analysis cell and pushing the liquid sample out of the analysis cell, wherein a first analysis measurement is allowed to be performed while a second portion of the plunger is arranged between a light source and a light detector; wherein the plunger is movable to a completely retracted position in the analysis cell for allowing a second analysis measurement to be performed such that light being detected by the light detector is passed through the liquid sample filling a space between opposite walls of the analysis cell.

A device for screening of a biological sample in a container includes a lighting system having a radiation source, an analysis station having an optical detector and controller. The lighting system includes a filter holder device for selecting two radiations with different wavelengths. The analysis station includes a system for optical detection of the container before analysis of the sample, which includes a backlight panel and an illuminator for illuminating the container and to allow the optical detector to acquire an image of the container and send to the controller information based on the image. The controller controls a rotation system, set up in the analysis station, to position the container so that, in the analysis phase of the sample, the radiation irradiates the sample at an inspection window and a label is arranged on an opposite side with respect to that from which the radiation originates.

An optical device includes: a light source part configured to project illumination light toward a sensing region; a photodetector configured to receive reflected light of the illumination light reflected on the sensing region; and a condenser mirror. The condenser mirror has a through hole through which the illumination light from the light source part passes and an optical axis of the light source part and an optical axis of the condenser mirror are aligned with each other. A reflection surface of the condenser mirror has a shape obtained by cutting out a columnar body extending in a projection direction of the illumination light, with a spheroid whose rotation axis is a major axis. The photodetector is disposed in a direction toward a first focal position of the condenser mirror. The sensing region is set in a direction toward a second focal position of the condenser mirror.

Apparatus and methods are described for use with a microscopy unit that comprises an objective lens and a microscope camera. A cantilever includes an objective lens housing. A motor moves the cantilever along a direction of the optical axis of the objective lens. The cantilever is configured, during the movement of the cantilever, to support the objective lens within the objective lens housing such that an optical axis of the objective lens is aligned with the camera, without the objective lens being directly connected to the camera. Other applications are also described.

Near-Infrared (NIR) filter photometry is used to calculate component concentrations in multiphase flows. The disclosed methodology adapts the Beer-Lambert law for nonhomogeneous immiscible mixtures (such as oil and water) by modeling the fluid layer as a nonhomogeneous distribution of its components and deriving a mathematical relationship between measured absorbances, component path lengths, and non-homogeneity factors. The methodology is integrated into a multi-channel filter photometer to measure phase concentrations in oil-and-gas pipelines. The system is proven more accurate than current state of the art based on data from simulations, multiphase flow laboratories and field trials.

A method includes receiving an x-ray signal transmitted from an x-ray transmitter through a coated separator membrane. The method also includes obtaining infrared (IR) signals from the coated separator membrane. The IR signals include two or more spectral components including peaks that include a first peak from the separator membrane. The method also includes the processor determining whether a second peak is present, and determining if at least one contaminant/additive exists in the coating present within the coated separator membrane. The method also includes calculating, by the processor, a concentration/area weight of the at least one contaminant/additive and a weight, density, or thickness of the coating.

A method of spectroscopically measuring percent glycated hemoglobin or a glycated hemoglobin:total hemoglobin ratio in a biological sample is disclosed. The method includes the use of a turbidity normalization algorithm to normalize the total hemoglobin concentration calculated from the spectroscopic measurements to substantially remove any turbidity interference therefrom. The turbidity normalization eliminates the negative bias observed with intralipid/lipemia and thus provides a glycated hemoglobin assay with no significant interference from intralipid/lipemia.

A method of spectroscopically measuring percent glycated hemoglobin or a glycated hemoglobin:total hemoglobin ratio in a biological sample is disclosed. The method includes the use of a turbidity normalization algorithm to normalize the total hemoglobin concentration calculated from the spectroscopic measurements to substantially remove any turbidity interference therefrom. The turbidity normalization eliminates the negative bias observed with intralipid/lipemia and thus provides a glycated hemoglobin assay with no significant interference from intralipid/lipemia.

Methods, apparatuses, and systems for improving gas detecting devices are provided. An example gas detecting device may include a receiver element. In some examples, the receiver element may include a sample filter component and a reference filter component. In some examples, the sample filter component may be positioned coaxially with the reference filter component.

A process for quantifying a concentration of a targeted molecule in a liquid sample in which a signal beam and a reference beam (and also optionally an interference beam) are pulsed, each beam being pulsed from its own source (preferably at narrow bandwidths), the pulsed beams are spatially combined into a single radiation beam which passes into the liquid sample and then pulsed output beams are detected after the single radiation beam passes out of the liquid sample. The pulsed signal beam output and the pulsed reference beam are processed to obtain a value over a preselected period of time and, if an interference beam is used, it is processed with the reference beam to obtain a calibration curve adjustment representative of optical interference represented by at least one interfering molecule concentration which is used to calculate the concentration level of the targeted particle in the liquid sample. Two detectors, which may have an optical co-axial configuration, can be used for detection of pulsed beams.