To acquire both excellent spectrum and sample image reflecting actual conditions of a sample, and to increase convenience of measurement, provided is a display device for a photometric analyzer, which is configured to irradiate a sample with light to analyze the sample, the display device being configured to display a measurement result of the photometric analyzer, and including: a controller; and a display, which is configured to display an image based on measurement data processed by the controller. The measurement data at least contains a spectrum indicating an intensity of emitted light, which is emitted by the sample irradiated with the light, and a sample image of the sample, which is taken by an imaging device. The display is configured to display the spectrum and the sample image in an arrangement in the same screen.

A time-resolved hyper-spectral imaging system for imaging a sample, includes a radiation source suitable for illuminating the sample repeatably, a first optical system configured to form an image I of the sample on a spatial light modulator forming a transmission or reflection mask P, a processor connected to the spatial light modulator and configured to make the transmission or reflection mask P vary for each repetition of the illumination, a second optical system suitable for focusing the radiation transmitted or reflected by the spatial light modulator so as to form, in its image focal plane, a partial image S=P.I, the imaging system being wherein it comprises: a dispersive device comprising a slit placed in the image focal plane of the second optical system, the dispersive device being suitable for spatially splitting the various wavelengths of the radiation transmitted or reflected by the spatial light modulator; a streak camera arranged so as to be illuminated by the radiation issuing from the dispersive device and configured to acquire a plurality of time-resolved partial images of the sample, the images being associated with respective and different transmission or reflection masks P, the streak camera being connected to the processor and the processor also being configured to combine the partial images of the sample so as to construct a 4D image cube I.sub.tot forming an image resolved in time and in wavelength of the sample; and corresponding time-resolved hyper-spectral imaging method for imaging a sample.

The invention provides a method for the selection of cultivation component batches to be used in the cultivation of a mammalian cell expressing a protein of interest wherein at least two different components are employed in the cultivation.

High-throughput hyperspectral imaging systems are provided. According to an aspect of the invention, a system includes an excitation light source; an objective that is configured to image excitation light onto the sample, such that the excitation light causes the sample to emit fluorescence light; a channel separator that is configured to separate the fluorescence light into a plurality of spatially dispersed spectral channels; and a sensor. The excitation light source includes a light source and a plurality of lenslet arrays. Each of the lenslet arrays is configured to receive light from the light source and to generate a pattern of light, and the patterns of light generated by the lenslet arrays are combined to form the excitation light. The objective is configured to simultaneously image each of the patterns of light to form a plurality of parallel lines or an array of circular spots at different depths of the sample.

A fluorescence photometer includes a photometer unit and an optical fiber unit. The photometer unit includes a light source, an excitation-side spectroscope for separating light emitted from the light source to generate excitation light, and a fluorescence-side spectroscope for separating fluorescent light emitted from a sample irradiated with the excitation light to generate monochromatic light. The optical fiber unit guides the excitation light to the sample placed outside the photometer unit and guides the fluorescent light emitted from the sample to the photometer unit and includes an image fiber for capturing an image of the sample, an excitation-side fiber arranged around the image fiber and for guiding the excitation light to the sample, and a fluorescence-side fiber arranged around the image fiber and to guide the fluorescent light emitted from the sample to the photometer unit. The excitation-side fiber and the fluorescence-side fiber are arranged to surround the image fiber.

The invention relates to a device for automatic species analysis and to a method for carrying out the same. In particular, the invention relates to a device for automatic species analysis within a large biological group and to a method for automatically carrying out such analyses. A device according to the invention for automatic species analysis within a large biological group comprises a first beam path (10), directed from a first laser radiation source (12) to a sample region (40), the fluorescence radiation emitted by a sample (42) within the sample region (40) as a result of excitation by the first laser radiation source (12) being collected and fed to a first spectrometer (14) for spectral evaluation; a second beam path (20), directed from a second laser radiation source (22) to the sample region (40), the fluorescence radiation emitted by the sample (42) within the sample region (40) as a result of excitation by the second laser radiation source (22) being collected and fed to a second spectrometer (24) for spectral evaluation; and a camera (30), which is designed to capture a photograph of the sample (42) within the sample region (40); the device also comprising a means for automatic species analysis (50), which is designed to carry out an automatic species analysis from the sample-related results of the spectroscopic evaluation of the first spectrometer (14) and of the second spectrometer (24) and the photograph of the camera (30) by means of a multi-step threshold value comparison for certain determination parameters stored in an associated database. A method according to the invention serves to carry out an automatic species analysis by means of a device according to the invention.

A method of illumating an item is disclosed. The method includes applying adhesive to the item, interspersing a taggant in the adhesive, illuminating the item with an excitation signal, sensing luminescence emitted by the taggant in response to illumination by the excitation signal, and determining the authenticity of the item based on the sensed emitted luminescence. The item can include any item benefited by authentication, and can include a postage stamp. A method of customizing an item is disclosed. This can include the steps of preparing a substrate, applying a security feature to the substrate, printing non-customized information on the substrate, receiving image information, and printing the image information on the substrate.

A method of illuminating an item is disclosed. The method includes applying adhesive to the item, interspersing a taggant in the adhesive, illuminating the item with an excitation signal, sensing luminescence emitted by the taggant in response to illumination by the excitation signal, and determining the authenticity of the item based on the sensed emitted luminescence. The item can include any item benefited by authentication, and can include a postage stamp. A method of customizing an item is disclosed. This can include the steps of preparing a substrate, applying a security feature to the substrate, printing non-customized information on the substrate, receiving image information, and printing the image information on the substrate.

A microscopy method includes illuminating an object with illumination light, recording a first color image of the illuminated object by a color image sensor suitable for recording colors of a first gamut, producing a second color image of the object, the second color image including pixels that each have assigned a color from a second gamut, depicting the second color image by a display apparatus suitable for rendering colors of the second gamut, wherein the producing the second color image includes determining the colors at the pixels of the second color image by applying a color transfer function to the colors of the corresponding pixels of the first color image, the color transfer function mapping input colors onto output colors, and the color transfer function mapping those input colors that belong to the first gamut but not to the second gamut onto output colors that belong to the second gamut.

A method of intimating an item is disclosed. The method includes applying adhesive to the item, interspersing a taggant in the adhesive, illuminating the item with an excitation signal, sensing luminescence emitted by the taggant in response to illumination by the excitation signal, and determining the authenticity of the item based on the sensed emitted luminescence. The item can include any item benefited by authentication, and can include a postage stamp. A method of customizing an item is disclosed. This can include the steps of preparing a substrate, applying a security feature to the substrate, printing non-customized information on the substrate, receiving image information, and printing the image information on the substrate.