Presented herein are methods, systems, and apparatus for single analyte detection or multiplexed analyte detection based on amplified luminescent proximity homogeneous assay (alpha) technology, but using hollow polymer fiber optics doped with acceptor bead dye (e.g., thioxene, anthracene, rubrene, and/or lanthanide chelates) or donor bead dye (e.g., phthalocyanine) that carry a signal generated by the dopant via singlet oxygen channeling.

The present disclosure relates to a sensor membrane for an optochemical sensor for determining a measurand correlating with a concentration of an analyte in a measuring fluid, comprising: a functional layer comprising a first polymer matrix doped with a luminescent dye whose emissivity after excitation with electromagnetic radiation can be changed by the analyte; and a second polymer matrix in which the functional layer is at least partially encapsulated and which is permeable to the analyte at least in a subregion facing the measuring fluid and adjacent to the functional layer, wherein the sensor membrane comprises an optically detectable substance, different from the luminescent dye, for marking the sensor membrane. The present disclosure further relates to a membrane cap having such a sensor membrane and an optochemical sensor.

An oxygen sensor has an oxygen sensitive fluorescent material including an oxygen sensitive dye and an oxygen insensitive dye, the oxygen sensitive dye and an oxygen insensitive dye being fluorophores; and a large diameter optical fiber. The large diameter optical fiber includes a first end and a second end. The large diameter optical fiber is configured to transit photons and transmit emissions from one or more of the fluorophores upon excitation thereof. The oxygen sensitive fluorescent material is located on the first end of the large diameter optical fiber.

An analyte indicator may include a porous base and may be included in an analyte sensor. The analyte indicator may retain its physical, chemical, and optical properties in the presence of compression. The porous base may not vary in opacity. The analyte indicator may include (i) a polymer unit attached or polymerized onto or out of the porous base and (ii) an analyte sensing element attached to the polymer unit or copolymerized with the polymer unit. The analyte sensing element may include one or more indicator molecule. The analyte sensing element may include one or more indicator polymer chains. The analyte indicator may include (i) an indicator polymer chain attached or polymerized onto or out of the porous base and (ii) indicator molecules attached to the indicator polymer chain.

An indicator and method of use thereof, and indicator system and method of use thereof are provided to determine the degree of an oxidative treatment. An indicator is incorporated into the oxidative treatment. The object and the indicator are subjected to the oxidative treatment. A discoloration of the indicator occurs based on an oxidation of the polymer by a process condition of the oxidative treatment oxidizing the polymer. The discoloration of the indicator is measured against a threshold color value to determine the degree of the oxidative treatment.

A composite comprises a polymer matrix and a luminophore dispersed therein. The composite is useful as a sensing film that is used as an optical sensor for oxygen measurement comprising the composite sensing film; a source of photons for photo-exciting the luminophores and a waveguide, transparent in the frequency range of the excitation photons, for guiding the excitation photons from the source to the composite sensing film; a detector for measuring properties of photons emitted from the luminophores. A system including a computer may be useful for coordinating the activities of the sensor.

Disclosed herein are polymeric dyes, their preparation, and their uses. Some embodiments relate to their use for detecting biological activity in samples, such as the presence of bacteria in blood.

A device for determining at least one condition parameter relating to a concentration or a partial pressure of an analyte in a gaseous medium, the device including at least one light source configured to emit light; at least one light receiver configured to detect the light; at least one optical sensor unit, and at least one temperature measuring device configured to measure a temperature of the optical sensor unit at least indirectly, wherein at least the light source, the light receiver and the temperature measuring device are arranged within a housing and at least the sensor unit is arranged outside of the housing, wherein at least one optical property of the sensor unit is a function of the condition parameter of the analyte, wherein light rays emitted by the sensor unit due to the sensor unit being irradiated by the light source are detectable by the light receiver.

An analyte indicator may include a porous base and may be included in an analyte sensor. The analyte indicator may retain its physical, chemical, and optical properties in the presence of compression. The porous base may not vary in opacity. The analyte indicator may include (i) a polymer unit attached or polymerized onto or out of the porous base and (ii) an analyte sensing element attached to the polymer unit or copolymerized with the polymer unit. The analyte sensing element may include one or more indicator molecule. The analyte sensing element may include one or more indicator polymer chains. The analyte indicator may include (i) an indicator polymer chain attached or polymerized onto or out of the porous base and (ii) indicator molecules attached to the indicator polymer chain.

This document describes a composite substrate for optical detection of a target gas composition within ambient gas in an environment. A composite substrate can include a porous polymer material incorporating a second material, and the second material can include at least one chemical property to establish or adjust a hydrophobicity of the porous polymer material. The composite substrate can also include at least one functionalized region, included such as to be exposed to the ambient gas the functionalized region including at least one electrical or optical property correlative of the target gas composition.