A sensing system for characterizing analytes of interest in a sample comprises a photonic integrated circuit with an integrated interferometer. The integrated interferometer is configured for spectroscopic operation. The integrated interferometer comprises at least a sensing arm and a reference arm, both the sensing arm and the reference arm having an exposable segment available for interaction with the sample, whereby the exposable segment of the reference arm has an optical path length which is smaller than twice the optical path length of the exposable segment of the sensing arm. The exposable section of the sensing arm is selective to the analyte of interest, whereas the exposable section of the reference arm is not selective to the analyte of interest.

A side illuminated multi point multi parameter optical fiber sensor that requires no sensitive coating is provided. This sensor comprises an optical fiber having at least one removed cladding section as the sensitive region, at least one probing light source that side illuminates the fiber, a power supply, a detector, a signal processor and a display. The sensitive optical fiber is optically affected by the presence of a measurand medium that can fluoresce, phosphoresce, absorb and/or scatter the probing light. This probing light is guided by the fiber core towards a detector which measures the light intensity and this light intensity is correlated with a measurand.

Disclosed is an optical fiber including a plasmonic optical filter with a closed curved shape provided at, at least portion thereof. A method of manufacturing the plasmonic optical filter includes a step of exposing a core, a step of forming a thin metal film on the core through physical vapor deposition while rotating the core in a circumferential direction after changing a rotation axis of the core, and a step of patterning nanopatterns on the cylinder-shaped thin metal film using focused ion beam technique assisted with endpoint detection method. Due to such constitutions, an active area to generate an optical signal for optical sensor can be increased.

Chalcogenide waveguides with high width-to-height aspect ratios and a smooth exposed surfaces can serve as mid-infrared evanescent-absorption-based sensors for detecting and identifying volatile organic compounds and/or determining their concentration, optionally in real-time. The waveguide sensors may be manufactured using a modified sputtering process in which the sputtering target and waveguide substrate are titled and/or laterally offset relative to each other and the substrate is continuously rotated.

A method of measuring a concentration of an analyte is provided, including: reacting a test solution including an analyte with a nanoparticle solution including a plurality of nanoparticles and an optical waveguide element to form a sandwich-like structure; and measuring evanescent wave energy of the optical waveguide element absorbed and/or scattered by the plurality of nanoparticles after the plurality of nanoparticles forming the sandwich-like structure by using a photodetector to obtain a first signal, and calculating the concentration of the analyte based on the first signal. Wherein, a detection recognition element is conjugated on a surface of each of the plurality of nanoparticles, and a capture recognition element is conjugated on a waveguide surface of the optical waveguide element.

An assay unit for carrying-out fluorescence-detected assays having a microfluidic chip with a microfluidic system to convey a sample or analyte solution through one or more microfluidic channels arranged on the chip, and a photonic system with two or more rectangular waveguide structures. The microfluidic channels and the waveguide structures cross each other at a detection site. In an assay area, where a certain microfluidic channel and a certain waveguide structure cross each other, one or more lateral surfaces of the core of the waveguide structure at least partially face an inner volume of the microfluidic channel, such that an evanescent field of light guided within the waveguide structure overlaps with a certain part of the inner volume of the microfluidic channel.

A system and method for forming a low cost optical sensor array. The sensor includes an optical fiber; a first nanocomposite thin film along at least a portion of the optical fiber for interrogating a first parameter through a correlated signal having a first wavelength; and a second nanocomposite thin film along at least a portion of the optical fiber for interrogating a second parameter through a correlated signal having a second wavelength different from the wavelength of the first parameter.

Provided are an optical sensor and an analyzer, including an optical sensor section in which a cladding layer of an optical fiber is removed so as to expose a core layer by a predetermined optical path length, and a protective material is added to a surface of the exposed core layer, the protective material having higher resistance to an organic solvent, base, or acid than that of the cladding layer; a light source device that causes light to enter one end of the optical fiber; a light receiving device that receives transmitted light emitted from another end of the optical fiber; and a control device that controls the light source device and the light receiving device to measure optical transmittance in the optical sensor based on a ratio of intensity of the light emitted from the light source device to intensity of the light received by the light receiving device.

The present disclosure relates to a biological detection chip and a detecting method thereof. The biological detection chip includes a light guiding substrate having a top surface, a bottom surface opposite to the top surface, and a side surface between the top surface and the bottom surface, and a biosensitive membrane on the top surface of the light guiding substrate.

Disclosed is an optical fiber including a plasmonic optical filter with a closed curved shape provided at, at least portion thereof. A method of manufacturing the plasmonic optical filter includes a step of exposing a core, a step of forming a thin metal film on the core through physical vapor deposition while rotating the core in a circumferential direction after changing a rotation axis of the core, and a step of patterning nanopatterns on the cylinder-shaped thin metal film using focused ion beam technique assisted with endpoint detection method. Due to such constitutions, an active area to generate an optical signal for optical sensor can be increased.