A fluidic valve for a sample separation apparatus for separating a fluid, wherein the fluidic valve comprises a stack of connected layer structures, a first conduit within the stack, a second conduit within the stack, a movable body within the stack, and an actuator configured for actuating the movable body to selectively bring the movable body into a flow enabling configuration in which flow of fluid between the first conduit and the second conduit is enabled, or into a flow disabling configuration in which flow of fluid between the first conduit and the second conduit is disabled.

A multi-way valve has an upper part, a lower part and a central part connected to the upper part via an interposing first membrane and the lower part via an interposing second membrane, wherein the upper and lower parts contain recesses on the upper and lower part faces facing the membranes, where a control fluid is introducible into the recesses, the central part contains a pair of openings in regions opposite the recesses on the central part faces lying adjacent to the membranes, where while introducing the control fluid into a recess, the membrane closes respective opposite openings in the central part, and where the membrane otherwise recedes into the recess, thereby releasing the opposite openings, where valve connections are mounted on the upper or lower part such that the central part can have a very thin design while preventing dead regions in the channel systems.

A flow path structure incorporated into a measuring device that facilitates maintenance, includes a base, and a flow path switch member provided in a flow path switch member accommodation part and measures a liquid to be measured. The base includes a separation element accommodation part to accommodate a separation element that separates a plurality of components included in the liquid to be measured, and the flow path switch member accommodation part provided at an intermediate part of a flow path that guides the liquid to be measured. The flow path switch member measures the liquid to be measured, and switches a state of a flow path inside the base between a first flow path state in which the liquid to be measured is guided outside the separation element accommodation part, and a second flow path state in which the measured liquid is guided inside the separation element accommodation part.

A high-pressure switching valve includes a stator and a rotor. The stator includes a plurality of ports where each port is connected at one end to a port connection and having at another end a predetermined port opening cross section at a stator end face of the stator. The rotor includes a rotor end face and at least one or a plurality of grooves. The rotor can be configured to have a rotary position with respect to the stator where two predetermined port opening cross sections connect to one of the grooves in a pressure-tight manner. The rotor and the stator can be pressed together in a sealing manner at the rotor end face and the stator end face in regions away from the port opening cross sections and the at least one or a plurality of grooves. The rotor and the stator each include a hard material. The rotor can be configured to wobble or tilt with respect to a rotational axis of the rotor.

A preparative chromatograph system includes a sample injector that injects a sample into a separation flow path (8) through which a mobile phase flows, a separation column that is provided on the separation flow path and is to separate a sample injected into the separation flow path into components, a detector that is provided at a position farther downstream than the separation column on the separation flow path and is to detect sample components obtained by separation in the separation column, a collector having a plurality of collection containers for collecting part of an eluate eluted from the separation column and a switch mechanism configured to be capable of selectively connecting a downstream end of the separation flow path to any one of the collection containers, a collection setter configured to set a portion, to be collected in each of the collection containers, of an eluate eluted from the separation column using a pre-acquired chromatogram of a sample, and a collection setter configured to be capable of setting a portion, including a sample component, of an eluate eluted from the separation column, and a portion, between two sample components that are adjacent to each other on the chromatogram, of an eluate eluted from the separation column, as the portion to be collected, and a controller configured to control an operation of the switch mechanism of the collector and collect the portion, which is to be collected and is set by the connection setter, in the predetermined collection container.

The invention relates to a method which realizes a two-dimensional separation of ionic species on the basis of the online coupling of ion chromatography (IC) and capillary electrophoresis (CE). A device for ICCE coupling, its implementation in terms of two alternatives, the connection to a mass spectrometric detector, and corresponding application are described.