An automated analyzer with an on-board fridge for long-term cooling of reagents, and a method for isolating and analyzing an analyte comprising long-term cooling of reagents.

The present invention generally relates to the determination of an analyte concentration (quantitative determination) or whether an analyte threshold level has been passed (qualitative determination) in a biological sample through employment of a disposable analytical microprocessor device. The device can include a batch-specific, self-executable algorithm for the calculation of the analyte concentration.

A diagnostic test reader system including two or more reader modules and at least one mother module is provided. Each of the reader modules includes a unique code and is configured for reading a specific test cartridge type. Each of the reader modules is configured to be in data communication with the mother module for receiving instructions from the mother module and for transmitting read and/or derived data to the mother module. The mother module is configured for communicating individually with each of the reader modules.

A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

A sealing apparatus is provided that enables a sealing agent bottle to be replaced with input of an inappropriate sealing agent prevented, and a cover slip, a sealing agent, and a clearing agent appropriately combined. A sealing apparatus (10) includes a starting bath (22) in which a clearing agent is stored and a slide glass (12) on which a specimen before the sealing is attached is dipped in the clearing agent, a sealing agent bottle (44) that stores a sealing agent dispensed onto the slide glass (12) taken out from the starting bath (22), and includes a recording unit (62) in which at least a type of the sealing agent is recorded, a storage unit (68) storing information on compatibility of the clearing agent with respect to a cover slip (26) and the sealing agent currently applied, and a control unit (66) that performs, when the sealing agent bottle (44) is replaced, control of determining the compatibility of the sealing agent read from the recording unit (62) with respect to the cover slip (26) and the clearing agent stored in the storage unit (68), and at least when the result of the determination is incompatible, making a notification unit (20) issue a notification indicating the incompatibility.

The invention is related to a pipette calibration managing system (PCMS), comprising a PCMS managing application to be hosted by the PCMS customer and to be run by a PCMS host server, which is accessible for clients via a data network and is configured for man-aging the access of the clients to PCMS data contained in a PCMS database stored in a PCMS data storage being located on premises of the PCMS customer, a client application to be run by a client computer and configured to communicate with the PCMS managing application via the data network, a calibration ordering software configured for providing the calibration order data to be transferred to a calibration service provider, the PCMS managing application being configured to receive calibration data from the calibration service provider via an external data network, in particular the Internet, and the PCMS data-base being configured to store the calibration data, which thereby form at least a part of the PCMS data. The invention also relates to a corresponding method.

A disposable fluidic cartridge has a recess therein. A mechanically-actuated mechanism is disposed within the recess for effecting an operation of the fluidic cartridge. The cartridge further comprises a machine-readable identification code on a breakable label covering at least a portion of the recess such that the portion of the breakable label covering the recess may be broken upon insertion of a mechanical actuator into the recess to actuate the mechanically-actuated mechanism. This renders the identification code unreadable and prevents reuse of the cartridge.

A microplate reader and a method for operating the microplate reader are disclosed. The microplate reader includes a housing, a first NFC reader/writer, a filter tray positioning device, a filter tray, an optical filter disposed in the filter tray, and a controller. The filter tray has a filter tray NFC tag disposed thereon and the filter has a filter NFC tag disposed thereon. The controller receives information about an assay protocol to be undertaken, wherein the assay protocol specifies a filter to be used. The first NFC reader/writer reads filter information stored in the filter NFC tag, the controller directs the NFC reader/writer to store the filter information in the filter tray NFC tag, and the controller enables operation of the microplate reader to undertake the assay protocol only if filter information indicates that the optical filter is in accordance with the filter specified in the assay protocol.

A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

An analysis system and a method for testing a biological sample are proposed, wherein certain pieces of at least two different pieces of control information are selected and/or used to carry out the test using a cartridge and/or certain pieces of at least two different pieces of evaluation information are selected and/or used to evaluate the measurement results determined by the test.