In some aspects, automated rapid antimicrobial susceptibility testing systems for performing a multi-assay testing sequence can include an automated incubation assembly having a nest assembly adapted to house at least one test panel having a plurality of wells for receiving a sample comprising microorganisms originating from a clinical sample, the incubation assembly facilitating incubation of one or more test panels in order to undergo the multi-assay testing sequence; a robotic handling assembly configured to accept one or more incoming test panels and move them to and from the incubation assembly for incubation between each assay of the multi-assay testing sequence; an automated liquid handling assembly configured to exchange one or more fluids in the plurality of wells of the test panels; and an optical assembly for interrogation and readout of each assay of the multi-assay testing sequence being performed in the plurality of wells.

A method to store sample tubes in a laboratory storage and retrieval system is presented. The laboratory storage and retrieval system comprises a storage section, a database comprising a sample tube inventory of the storage section, a control device, and at least one sample tube transport system. The storage section comprises at least two storage subsections. In a first step of the method, the control device identifies at least two sample tubes with at least one substantially identical sample tube attribute and distributed over the at least two storage subsections. In a second step of the method, the at least one sample tube transport system consolidates the at least two sample tubes in at least one storage subsection, wherein the control device further determines in which of the at least two storage subsections the identified sample tubes are consolidated.

Automated analyzer (2000) comprising a housing (2010, 3010), a robotic arm comprising an end effector (2360), the end effector (2360) comprising a body (2320) rotatably connected to an articulating arm and first (2363a) and second fingers (2363b) coupled to the body (2362) and being moveable relative to each other in a first direction, each of the fingers (2363a, b) having an engagement feature (2361) projecting inwardly from each of the first and second fingers (2363a, b) and toward the other of the first and second fingers (2363a, b). The automated analyzer (2000) further comprises a shuttle platform (2030) for receiving a shuttle (2030) carrying sample containers (03), the containers carrying sample (03) to be evaluated by the analyzer (2000) and the shuttle platform (2030) comprising a jaw assembly that engages the bottom portion of the sample containers when the jaw assembly is in the closed position.

Various embodiments include a sample storage system having: a transport module; a storage module coupled with the transport module on at least one side of the transport module, the storage module for storing a plurality of specimen tubes or microtiter plates; a tube selector module coupled to an end of the transport module for selecting at least one of the plurality of specimen tubes or microtiter plates; and an input/output (I/O) module coupled with the transport module on a side of the transport module, wherein the transport module is configured to modularly couple with at least one additional storage module for storing a plurality of specimen tubes or microtiter plates.

A slide rack carousel is provided that includes a base that is configured to support a plurality of slide rack spacers that extend upward from an upper surface of the base. Adjacent slide rack spacers define a slide rack slot of a predetermined size. The plurality of slide rack spacers may include slide rack spacers of varying sizes and therefore a plurality slide rack slot sizes can be selectively configured on the carousel in accordance with the positioning and size of the plurality of slide rack spacers that are attached to the base of the carousel. Accordingly, a desired number of 13 slide rack slots and a desired number of 23 slide rack slots can be configured on the base of the slide rack carousel.

The present invention provides an automatic analysis device and an automatic specimen processing system having a component-rack supply mechanism that, in a state where a plurality of component racks each having a disposable component mounted thereon are stacked, separates only a component rack at the leading stage of the stack from the other component racks, and supplies the separated component rack to the automatic analysis device or the automatic specimen processing system. Specifically, the automatic analysis device and the automatic specimen processing system have a supply mechanism including a separation mechanism that, in a state where a plurality of component racks are stacked, separates only a component rack at the leading stage of the stack from the other component racks, where the separation mechanism includes a movable mechanism having a pair of downward-movement prevention members that can separate the leading stage from the second stage of the stacked component racks; and a correction mechanism having a pair of correction members that correct a positional deviation of the component racks in order to avoid an influence of the positional deviation of the stacked component racks.

An automatic analyzer for analyzing samples includes a lift, a part take-out station and a rack recovery station. The lift is configured to raise and lower a plurality of stacked part racks to the part take-out station and to the rack recovery station while keeping the part racks together. The part take-out station comprises a first rack separator configured to prevent the uppermost one of said stacked part racks from being lowered when the lift lowers, while allowing the other part racks to lower, so that the uppermost rack is separated from the other part racks so as to remain in the part take-out station. The rack recovery station comprises a second rack separator configured to prevent the uppermost one of said stacked part racks from being lowered when said lift lowers, while allowing the other part racks to lower, so as to remain in the rack recovery station.

A plate transport device includes a main body, first and second moving members and first and second elastic members. The main body has an intermediate supporter. The first and second moving members have first and second supporters, respectively. The first and second moving members are supported to be movable in a first direction with respect to the main body. The first elastic member is provided between the intermediate supporter and the first supporter, and supplies a first biasing force directed toward the intermediate supporter in the first direction to the first moving member. The second elastic member is provided between the intermediate supporter and the second supporter, and supplies a second biasing force, which is directed toward the intermediate supporter in the first direction and opposite to the direction in which the first biasing force is directed, to the second moving member.

The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.

We describe a method for conducting an assay in a multi-well assay plate using an apparatus comprising a light detection subsystem, a liquid handling subsystem, and a plate handling subsystem. This is particularly well suited for conducting automated sampling, sample preparation, and analysis in a multi-well plate assay format. For example, it may be used for automated analysis of particulates in air and/or liquid samples derived therefrom in environmental monitoring.