A fluid container holder includes a body having a receptacle configured to receive a container. The body has a conductive outer surface for connection to an electrical ground or voltage source, and the holder is not formed solely of an electrically conductive metal. A fluid container handling assembly includes a drawer having a holder supporting a fluid container, and a frame supporting the holder. The frame is movable between a first position providing access to the holder and a second position positioning the holder within the instrument. The assembly also includes a first lock securing the holder to the frame when the frame is at the first frame position and unlocking the holder from the frame when the frame is at the second frame position. The assembly also includes a holder transporter configured to move the holder between a first holder position and a second holder position within the instrument.

A robotic sample handling system (100) may be provided for performing sample handling tasks in a laboratory environment. The system may comprise at least one robotic arm (140), (142) which is controllable to be positioned in a plane parallel to a work area and along a Z-axis perpendicular to the work area, and a controller (180) configured to control the robotic arm to position and operate the robotic arm as part of a sample handling task. The work area may comprise a module (204) for use with one or more of the samples, wherein the module comprises a mechanism which is actuatable by downward force, and wherein the controller is configured to control the robotic arm to actuate the mechanism by pushing downward in Z-direction. For example, the module may be a stand (204) for a sample container which comprise a push-push mechanism which may be operated by the robotic arm to bring the sample in the sample container in a vicinity of an effector, such as a magnet or a heat source.

A tray feeder mechanism comprising a plurality of trays within a tray feeder, each tray including a tray handle, and a gripper positioned within a gripping area defined by the tray handles, wherein the gripper is configured to remove a tray from the tray feeder when the tray feeder stops.

The specimen treatment and measurement system 2000 according to the present invention is provided with: a movement stage 2300 having a plurality of treatment lanes for treating specimens in parallel; a consumables supply module 2100 for storing consumables for use in treatment of the specimens, and supplying the consumables to the movement stage 2300; a cartridge supply module 2500 for storing cartridges for use in treatment of the specimens, and supplying the cartridges to the movement stage 2300; and a stage transfer mechanism 2400 for transferring the movement stage 2400 to each module. The cartridge supply module 2500 has a plurality of cartridge cartons for accommodating the cartridges stacked on top of each other, and a push-out mechanism for pushing cartridges out of a cartridge carton to a supply position of the cartridge supply module 2500.

The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.

An instrument for processing a biological sample includes a chassis. Connected to the chassis is a tape path along which a tape with a matrix of wells can be automatically advanced through the instrument, a dispensing assembly for dispensing the biological sample and a reagent into the matrix of wells of the tape to form a biological sample and reagent mixture, a sealing assembly for sealing the biological sample and reagent mixture in the tape, and an amplification and detection assembly for detecting a signal from the biological sample and reagent mixture in the matrix of wells in the tape.

A plate changer includes a plate storage that includes therein a plate setting base, and is provided with a transport window for retrieving, in one direction in a horizontal plane, a sample plate set on the plate setting base; and a transport mechanism that has at least a pair of holding portions holding both side surfaces of a sample plate, and holds and transports the sample plate by the holding portions. The plate storage has a plate guide that supports a side surface of the sample plate set on the plate setting base and guides the sample plate to a predetermined setting position. When the holding portion is inserted into the plate storage from the transport window, the plate guide is configured to move to a position not interfering with the action of the holding portion.

A plate changer includes a casing that stores a sample plate and one or a plurality of first rack plates that each support the sample plate. One or a plurality of plate supporters that respectively support the one or plurality of first rack plates at different heights are provided in the casing. Each first rack plate is configured to be supportable on and removable from any of the one or plurality of plate supporters. The plate changer further includes a detector that detects whether the first rack plate is supported on each plate supporter.

A module for an automated biology laboratory system includes a housing and a storage device located within the housing. The storage device has a plurality of plate slots for receiving microplates or lab-ware with a microplate footprint or containers. The laboratory system further includes a transfer slot to transfer the microplates or containers between an inside of the module and an outside of the module; indexing means to facilitate alignment of the transfer slot with a microplate transfer interface comprising an aperture of the housing; and connection means for fixedly connecting the transfer interface of the module to a transfer interface of an adjacent module.

A tray engine includes a vertical drive column, a rotation mechanism for rotating the vertical drive column, and an end effector attached to the vertical drive column. The end effector includes an end effector base attached to the vertical drive column. The end effector further includes a slide attached to the end effector base to support a tray, when present. The slide enables the tray to slide along a length of the end effector base. The tray engine includes a drive mechanism attached to the end effector base for moving along the length of the end effector base to enable the tray, when present, to slide linearly along the length and load or unload the tray to or from the slide.