A cartridge (10) for injecting a pharmaceutical solution includes at least one flexible small bag (18, 22) made of thin film walls, having a chamber (12, 14) containing a pharmaceutical substance (S, P, L) and having a head surface (37) being outwardly convex. A syringe (100) for injecting a pharmaceutical solution (S) includes a body (102) extended along a main axis (X), an accommodating space (120) to accommodate a cartridge (10), and a plunger (110) with a head (113) being dome-shaped and convex towards the space (120), preferably asymmetrical with respect to the main axis (X). An injection kit for injecting a pharmaceutical solution including a syringe (100) and at least one cartridge (100).

An apparatus for delivering a therapeutic agent may be associated with a cap for a bottle that contains a prescription for a drug to which the therapeutic agent corresponds. When the prescription bottle contains an opioid, the therapeutic agent may comprise a substance that counteracts the effects of the opioid. The apparatus may include a nozzle that facilitates nasal administration of the therapeutic agent. The apparatus may be capable of attaching to a cap for a prescription bottle, or the apparatus may have a configuration that enables it to serve as the cap for the prescription bottle.

An extender for filling a syringe cartridge at a filling station having an elevating bar has a connector portion connecting a proximal portion of the extender to a distal portion of the syringe cartridge. A head on a distal portion of the extender is sized and shaped to engage the elevating bar of the filling station. The syringe cartridge having the extender may be provided to a filling station that is configured for filling a long syringe cartridge having a long syringe-cartridge length greater than a length of the syringe cartridge. The syringe cartridge and extender may be supported on a syringe support of the filling station and passed through the filling station to fill the syringe cartridge.

The present disclosure relates to devices and methods for neutralizing an acidic anesthesia solution. An anesthesia neutralization device includes an outer housing and an inner housing. The inner housing holds a buffer carpule and an anesthetic carpule in a side by side arrangement, with the buffer solution maintained under pressure prior to deployment. A curved transfer needle is coupled to the outer housing and includes ends that both point respectively toward the buffer carpule and anesthetic carpule. The device is actuated by moving the inner housing relative to the outer housing to bring the anesthesia carpule and buffer carpule into contact with the transfer needle and to force buffer solution through the transfer needle and into the anesthesia carpule.

The one or more embodiments disclosed herein provide a method for automatically assembling multiple compounds into a single edible custom composition, in which each compound is individually customized to proportions formulated from a profile of an individual or group. The single custom mixture can contain a plurality of compounds including foods or flavors, nutritional additives, herbals, biologics, or pharmacologically active substances. Using the method and a related algorithm, the formulation of a custom mixture is suggested.

Devices and methods for filling a medicament cartridge of a pump, including a user-wearable, ambulatory infusion pump. A device for supporting a medicament cartridge can comprise a body portion resembling a tray, with recesses disposed therein to support one or more of a cartridge body, cartridge tubing, interconnect fitting, and vial adapter. The recesses of the tray may be shaped to correspond to that component intended to be placed in its respective recess so to provide a visual indication to a user how to couple and align the various components necessary to fill the cartridge.

The present invention provides a lyophilized formulation containing a therapeutic agent and a surfactant sealed in a glass container, wherein an inner surface of the glass container is sulfur-treated or VIST-treated.

A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.

A medicament container for a syringe or carpule has a base body surrounding an interior at least in sections. The base body has a central axis and a proximal opening. An end plug is arranged in the interior such that the end plug in the interior is displaceable along the central axis and separates a first proximal region of the interior from a second distal region of the interior. A plug securing part is at least partially insertable into the second region through the proximal opening. When inserted into the interior, the plug securing part is arranged closer to the proximal opening than the end plug and is fixedly held in the interior by the positive and/or non-positive connection at least in a holding area.

A device and method for testing and inspecting the integrity of an autoinjector device is disclosed. The autoinjector devices includes a medication container, a housing that receives the medication container, the housing including a plurality of electrodes arranged circumferentially relative to the medication container, and a plurality of electrical contacts corresponding to the plurality of electrodes and in electrical communication therewith, the electrical contacts being accessible from the exterior of the autoinjector device, wherein a circuit between at least one pair of electrodes, measured at the electrical contacts, indicates a defect in the medication container. A method of testing the integrity of the autoinjector device is also disclose, wherein a voltage is applied to the electrical contacts in order to determine the integrity of the medication container in the autoinjector device. Accordingly, defects in the pre-packaged medication container in the autoinjector device may be detected.