A hollow body includes a wall which at least partially surrounds an interior volume of the hollow body. The wall includes a layer of glass and has a wall surface. The wall surface includes a surface region in which the layer of glass is at least partially superimposed by a plurality of particles. The plurality of particles is characterized by a particle size distribution having a D.sub.50 in a range from 1 to 100 μm. A hollow body having a wall surface including a surface region which is characterized by a coefficient of dry sliding friction of less than 0.15 is also provided.

An example of an electronic medical fluid transfer device can comprise a fluid transfer module with a multidirectional flow control valve and an intermediate container or pumping region, a sensor configured to detect whether at least one of a vacuum or gas is present in the fluid transfer module, a first electromechanical driver configured to interface with and control the multidirectional flow control valve on the fluid transfer module, a second electromechanical driver configured to be mechanically linked to and control the intermediate container or pumping region according to an operational parameter, and one or more computer processors configured to communicate electronically with the sensor and the first and second electromechanical drivers to determine the operational parameter based on a flow characteristic of medical fluid to be transferred and adjust the operational parameter based on output of the sensor.

The disclosure is directed to pharmaceutical compositions comprising esketamine or a pharmaceutically acceptable salt thereof and an oxidative degradant. In certain aspects, the oxidative degradant is 6-(2-chlorophenyl)-6-oxohexanoic acid or a pharmaceutically acceptable salt thereof. Methods for limiting the formation of oxidative degradants in a pharmaceutical composition comprising esketamine or a pharmaceutically acceptable salt thereof are also disclosed.

A medicine dispensing device, configured to contain a liquid medicine to be dispensed by the medicine dispensing device and having a plurality of dosing indicia spaced apart from each other around and in relation to a circumference of a surface of the medicine dispensing device, each dosing indicia being of a different height relative to a reference level and corresponding to different dose of the liquid medicine.

Glass articles with coatings are disclosed herein. According to embodiments, a glass article may include a glass body comprising glass and having a first surface and a second surface opposite the first surface, wherein the first surface is an exterior surface of the glass body. A coating disposed on at least a portion of the exterior surface of the glass body. The coated glass article may have an effective throughput rate greater than or equal to 1.10×R.sub.T, wherein R.sub.T is the effective throughput rate of an uncoated glass article in units of parts per minute (ppm).

Glass articles with coatings are disclosed herein. According to embodiments, a glass article may include a glass body comprising glass and having a first surface and a second surface opposite the first surface, wherein the first surface is an exterior surface of the glass body. A coating disposed on at least a portion of the exterior surface of the glass body. The coated glass article may have an effective throughput rate greater than or equal to 1.10×R.sub.T, wherein R.sub.T is the effective throughput rate of an uncoated glass article in units of parts per minute (ppm).

A hollow body includes a wall which at least partially surrounds an interior volume of the hollow body. The wall comprises a layer of glass comprising a first glass composition, comprises a base surface, and has a wall surface. The wall surface comprises at least one surface region, in which the base surface is at least partially superimposed by at least one elevated region, and at least one contact region, which extends along a contact range of a height of the hollow body. The at least one elevated region comprises a further glass composition. An exterior diameter of the hollow body has a maximum throughout the contact range. The at least one surface region is at least partially positioned in the at least one contact region.

The embodiments relate to improved skin quality, health and appearance using a new delivery method and certain bioactive compositions and formulations. The system incorporates microneedle delivery technology with unique compositions and formulations. Such development allows for the pursuit of personalized medicine, or treatment delivery that can expand to remote controlled environment, immediate compounding and ultimate personalization with a state of the art longitudinal data predictive analytics. Certain formulations described herein are unique, combinatory and synergistic. Secured by high-tech proprietary system, there are unlimited potentials using AQT technology including but not limited to 3-D printing of a biodegradable micro chips that can be delivered via injection, AQT or any other possible route.

A vial container is disclosed to have a base, body, and top portion. The body portion is structured to have at least three flat sides and an optional neck or collar to attach lids or caps. The inner cavity with longitudinal corners of adjoining sides provide a method to accumulate remaining medicinal elements for extraction.

The current pandemic due to Covid-19 stresses the importance of effectively treating highly contagious and deadly infections. The described medical device is meant to help the medical community by enabling them to treat patients more effectively. The delivery mechanism focuses on the mucous membrane. It is noninvasive and easy to use by patients directly. The device is hand-held, with incorporated germicidal UVC lights. It has two chambers connected by an internal application tip. The tip connects to a removable container which can be used with the prescribed treatment/therapy, vaccine, or viral testing fluid/reagent, as needed. Due to its versatility, non-invasive nature and germicidal properties, this device supports rapid response to infectious diseases, such as COVID-19. It may also further promote the development and use of different inoculation and drug techniques and delivery systems by enabling easy administration, via the mucous membrane.