An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.

A vial cap is configured to releasably contain a portion of a material, for example a powdered medication, for dispensing into a container. Via operation of a depressable plunger, the material is released into the container for rehydrating and mixing with a liquid, and thereafter may be extracted, such as via a needle. In this manner, a rehydrated medication may be provided in a predetermined amount and at a desired time.

A borosilicate glass for a pharmaceutical container having high appearance quality, particularly a small number of air lines, and a glass tube for a pharmaceutical container are provided. The borosilicate glass for a pharmaceutical container contains, in mass %, from 70.0 to 78.0% of SiO.sub.2, from 5.0 to 8.0% of Al.sub.2O.sub.3, from 5.0 to 12.0% of B.sub.2O.sub.3, from 0 to 4.0% of CaO, from 0 to 4.0% of BaO, from 4.0 to 8.0% of Na.sub.2O, from 0 to 5.0% of K.sub.2O and from 0.001 to 1.0% of SnO.sub.2.

A method of providing a remedy is described. The method includes: (i) receiving, from a client device, answers to one or more of sets of questions that are relevant to one or more ailments and/or one or more unique expressions of the ailments; (ii) grading the answers using one or more remedy appropriateness values to produce graded answers, and wherein an remedy appropriateness value quantifies clinical importance of a remedy with respect to a question that is answered; (iii) scoring one or more remedies based on the graded answers to arrive at one or more remedy scores and identifying one or more top remedies that have high remedy scores; (iv) choosing, from a library of frequency files, one or more frequency files that correspond to one or more of the top remedies; and (v) presenting the frequency file as a remedy to the client device.

A transport and packaging container for a plurality of pharmaceutical containers and a method for transferring the pharmaceutical containers from the transport and packaging containers into a clean room are provided. By placing a side wall of the transport and packaging container in close proximity to or in contact with the side wall of the clean room and by opening the side wall of the transport and packaging container and a transfer port door of the clean room, the pharmaceutical containers can be transferred into the inside space of the clean room via the access opening.

A dispenser actuator assembly (100) has base member (102) and an actuator arm (104) that is configured to crush a glass ampoule assembly (10). The glass ampoule assembly (10) has a rupturable glass ampoule (12) containing a flowable material (M). The glass ampoule (12) is contained within an outer container (14), the outer container (14) having a first open end (22) and a second closed end (24). The glass ampoule assembly (10) has an applicator (16) positioned in the first open end (22). The dispenser actuator assembly (100) has the base member (102) that is configured to mount on the outer container (14). The actuator arm (104) is pivotally connected to the base member (102). The actuator arm (104) is pivotable from a first position to a second position that is configured to engage the outer container (14) to crush the glass ampoule (12) wherein the flowable material (M) is dispensed from the glass ampoule assembly (10).

A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The container exhibits a ratio of a break loose force (BLF) relative to a glide force (GF) of BLF/GF≤2 during a break loose and glide force test and a total glide force variation TGFV=GF.sub.max−GF.sub.min measured when the stopper is moved from a start position to its end position is TGFV<2 N.

Provided is a packaging system for an oxygen-sensitive compound (a drug, such as DHE, or an excipient such as exametazime), the system including a container, a self-activated oxygen scavenger (including an iron-based or non-iron based) and an oxygen-impermeable enclosure (e.g., an aluminum pouch). Also provided is a method of producing an oxygen-sensitive compound.

A method of powderizing a dry cake pharmaceutical drug product for injection within a vial may include securing a vial containing a dry cake pharmaceutical drug product for injection to a shaker device and powderizing the dry cake pharmaceutical drug product within the vial by shaking the vial with the shaker device operated at between about 100 to about 5000 cycles per minute for between about 10 minutes and about 1 hour.

The present invention provides, medical rubber parts that do not physically and chemically affect the quality of preparations. The present invention relates to a medical rubber part obtained by press-molding an unvulcanized rubber mainly containing a rubber for forming a liquid-contacting portion and an unvulcanized rubber mainly containing a butyl-based rubber for forming a non-liquid-contacting portion, wherein a color difference dE between the liquid-contacting portion and the non-liquid-contacting portion is 6.0 or more in NBS units.