A closure for dispensing one or more active agents into a container comprises a sealed or sealable chamber having a breakable wall and a hollow piston slidably mounted in a piston guide. Said hollow piston comprises an outer wall having an end in the chamber and at least one ventilation aperture. Said end has a cutting formation. Said hollow piston is slidable in the piston guide between a ventilation position in which the at least one ventilation aperture allows ventilation of the chamber and a sealed position in which the at least one ventilation aperture is sealed to prevent ventilation of the chamber and a deployed position in which the cutting formation has broken through at least a portion of the breakable wall. The outer wall has a retaining formation which engages with the piston guide to releasably resist sliding of the hollow piston between the ventilation position and the sealed position and the deployed position. The hollow piston may have an outer wall, and said outer wall has an end within the chamber, facing the breakable wall, wherein the cutting end has a first edge having a cutting formation and a gap in said cutting formation.

A closure for dispensing one or more active agents into a container comprises a sealed or sealable chamber having a breakable wall and a hollow piston slidably mounted in a piston guide. Said hollow piston comprises an outer wall having an end in the chamber and at least one ventilation aperture. Said end has a cutting formation. Said hollow piston is slidable in the piston guide between a ventilation position in which the at least one ventilation aperture allows ventilation of the chamber and a sealed position in which the at least one ventilation aperture is sealed to prevent ventilation of the chamber and a deployed position in which the cutting formation has broken through at least a portion of the breakable wall. The outer wall has a retaining formation which engages with the piston guide to releasably resist sliding of the hollow piston between the ventilation position and the sealed position and the deployed position. The hollow piston may have an outer wall, and said outer wall has an end within the chamber, facing the breakable wall, wherein the cutting end has a first edge having a cutting formation and a gap in said cutting formation.

A method and device for conveying tracking and communicating information concerning a dispensed fluid, the device including a measured dispensing device attached to a flexible collapsible container, the device including a sensor for measuring a physical property relating to the dispensing operation, and a communication device configured to communicate information determined by the sensor to a remote device.

A sealing cap for a container for holding a medical liquid comprising a cap body, which bounds an interior and has at least one opening, and at least one connection device, which is arranged on the cap body and to which a conveying device for feeding a medical liquid into the container or for removing a medical liquid from the container can be connected. The connection device has a sealing element, arranged on the cap body. The connection device has a break-off piece, which, in an initial state, is firmly connected to the cap body and covers the outer face of the sealing element in the outward direction. The break-off piece is connected to the cap body by means of a pre-determined breaking point. In addition, the sealing element is convex on the outer face.

A disposable container for containing a patient-customized medicinal fluid as a flowable material, which is adapted to dispense and seal the flowable material, the disposable container including: a plurality of container portions adapted to form spaces containing the flowable material; a bonding portion extended from tops of the container portions in such a manner as to come into contact with a surface of a film protecting the flowable material from the outside; and discharge portions extended from undersides of the container portions in such a manner as to be separable from the containing portions to discharge the flowable material to the outside, wherein the bonding portion connects the container portions with each other.

A container, in particular an ampule, of a plastic material has a container part (10) for receiving the contents of a container (14) to be dispensed via a container opening (12). Opening (12) is closed by a head part (18) that can be separated along a separation line (16). The head part (18) is adjoined by a neck part (20), which has a plurality of different functional surfaces on the inner circumference. One functional contact surface (44) is used to seal against a withdrawal body (32), which is provided for withdrawing the contents of a container (14) when the container opening (12) is opened. A lead-in area (50) is provided as a further functional surface on the interior of the neck part (40) and differs geometrically from the functional contact surface (44). The lead-in area (50) seamlessly merges into the functional contact surface (44). The lead-in area (50) and the functional contact surface are located between the other functional surfaces in the neck part (20).

A system includes a cap for a medical fluid container and an attachment part. The cap includes at least one first port. The first port includes a septum and a connection structure. The attachment part includes a hollow spike and a joining structure in fluid communication with the hollow spike. The joining structure is configured for connecting the device for withdrawing fluid from the fluid container and/or for supplying fluid into the fluid container. The connection structure is configured to be connected to a complementary connection structure of the attachment part in a releasable or non-releasable manner such that the hollow spike of the attachment part pierces the septum.

An apparatus and method of using a device for dispensing fluid comprising a flexible and collapsible container, a fluid dispenser pump connected to the flexible and collapsible fluid container configured to draw fluid from the flexible and collapsible fluid container into the fluid dispenser pump and to dispense fluid through a fluid delivery channel to an exit port upon actuation of the pump. The dispenser pump having an actuator comprising a dose delivery button, and a sensor located in the apparatus and configured to actuate the dispenser pump upon physical contact of the dose delivery button by a user.

Method for the aseptic filling of a bag with a pharmaceutical product or liquid which comprises the following steps: a) a first step in which the cap is inserted in the inlet of the bag; b) a second step in which said cap is raised and the pharmaceutical product or liquid concerned is introduced; c) a third step in which the cap is re-inserted in the inlet of the bag; and d) a fourth step in which the cap and the inlet of the bag are welded.

An apparatus and method for aseptically filling a container utilizing an adaptor formed of severable and heat-sealable material connected to a tube and container. The adaptor includes a membrane which is unsealed to allow filling by a known filling machine. Once the adaptor tube and container is formed as a unit, it is sterilized. The adaptor is then severed and sealed, creating a usable aseptic liquid product.