A pH-weighted chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) method and system are provided that works by indirectly measuring the NMR signal from amine protons found on the backbones of amino acids and other metabolites, which resonate at a frequency of +2.8-3.2 ppm with respect to bulk water protons. The technique uses a modified magnetization transfer radiofrequency saturation pulse for the generation of image contrast. A train of three 100 ms Gaussian pulses at high amplitude (6 uT) or Sinc3 pulses are played at a particular frequency off-resonance from bulk water prior to a fast echo planar imaging (EPI) readout, with one full image acquired at each offset frequency. This non-invasive pH-weighted MRI technique does not require exogenous contrast agents and can be used in preclinical investigations and clinical monitoring in patients with malignant glioma, stroke, and other ailments.

The present disclosure discusses systems and methods for imaging tissue. The system can reduce the amount of vibrations that are transmitted from a magnetic resonance imaging device to a tissue sample. The system can include a stabilization platform with at least one vibration dampener coupled towards either end of the stabilization platform. A fluid reservoir is coupled to the stabilization platform and a resonator is coupled to the exterior of the fluid reservoir.

In a method and computer for creating a pulse sequence for controlling a magnetic resonance (MR) tomography system to generate image data, raw MR data are acquired by exciting different transverse magnetizations in a number of sub-volumes of the subject, with a sequence of pulse iterations being executed that each prepare, excite and read out sub-volumes. The pulse iterations are designed so that a readout occurs when the pulse sequence is applied between a preparation of two spatially directly adjacent sub-volumes.

A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report.

A method for obtaining magnetic resonance imaging (MRI) echo-planar image (EPI) data, including providing a homogeneous, static background field; providing a gradient field to select a slice of an object for imaging; applying Radio-frequency (RF) pulses to excite magnetic resonance in the selected slice; and measuring a radio frequency signal emitted by the selected slice containing image data. The RF pulses are repeatedly applied separated by a time period shorter than a recovery time of static material in the selected slice such that the static material remains in a state of magnetic saturation, while dynamic material arriving within the slice since a previous RF pulse is not magnetically saturated.

An apparatus and method are provided for transmitting control information and data in an SC-FDMA communication system. The method includes placing a reference signal onto one middle symbol among a plurality of symbols in one slot, wherein the one slot is one of two slots in one subframe; placing CQI information onto at least one symbol of other symbols except for the one middle symbol; placing the data onto the other symbols except for the one middle symbol; placing a HARQ-ACK onto two symbols, wherein the two symbols are directly adjacent to the one middle symbol; and transmitting a signal including the reference signal, the data, the CQI information, and the HARQ-ACK. The HARQ-ACK is placed onto a position of at least part of the data. The symbols are SC-FDMA symbols, the one middle symbol is a 4th symbol, the two symbols are a 3rd symbol and a 5th symbol.

In various embodiments, the invention teaches systems and methods for magnetic resonance imaging. In some embodiments, the invention teaches systems and methods for determining the source of pain in intervertebral discs by measuring one or more physiological biomarkers associated with disc pain and/or disc degeneration.

A system and method is provided that includes acquiring chemical exchange saturation transfer (CEST) data with the MRI system and generating an acquired Z-spectrum (Z) from the CEST data. The system and method also includes computing an estimated direct water saturation (Z) based using at least one of relaxation measurements derived from the CEST data or imaging parameters used to acquire the CEST data with the MRI system, computing a direct saturation corrected Z-spectrum (Z) using the acquired Z-spectrum (Z) and the estimated direct water saturation (Z), and generating a CEST image of the subject using the direct saturation corrected Z-spectrum (Z).

A magnetic resonance imaging apparatus according to an embodiment includes processing circuitry. The processing circuitry performs at least one of data collection for collecting first data of an imaging region of a subject at a plurality of time intervals after a tag pulse is applied to fluid flowing into the imaging region, and data collection for collecting second data of the imaging region by differing at least one of applying or not-applying the tag pulse and a position of the applying. The processing circuitry performs phase correction for at least one of the first data and the second data by using data in which the longitudinal magnetization of the fluid is a positive value, to generate an image for each time phase.

In a method for automatic control of an examination sequence in magnetic resonance (MR) system during recording of MR signals in an examination segment of a person being examined, which has two tissue components with two different MR resonant frequencies, an examination sequence for examination of the examination segment is determined. Further, whether the examination sequence includes an imaging sequence in which one of the two tissue components is to be suppressed and for which at least two different suppression options exist to reduce the one of the two tissue components during the recording of the MR signals is determined. In response to the determination that the examination sequencing included the imaging sequence, the method can include determining a sequence parameter of the examination for the imaging sequence; and selecting one of the at least two suppression options as a function of the sequence parameter determined for the imaging sequence.