Systems and methods related to polymer foams are generally described. Some embodiments relate to compositions and methods for the preparation of polymer foams, and methods for using the polymer foams. The polymer foams can be applied to a body cavity and placed in contact with, for example, tissue, injured tissue, internal organs, etc. In some embodiments, the polymer foams can be formed within a body cavity (i.e., in situ foam formation). In addition, the foamed polymers may be capable of exerting a pressure on an internal surface of a body cavity and preventing or limiting movement of a bodily fluid (e.g., blood, etc.).

A closure for dispensing one or more active agents into a container comprises a sealed or sealable chamber having a breakable wall and a hollow piston slidably mounted in a piston guide. Said hollow piston comprises an outer wall having an end in the chamber and at least one ventilation aperture. Said end has a cutting formation. Said hollow piston is slidable in the piston guide between a ventilation position in which the at least one ventilation aperture allows ventilation of the chamber and a sealed position in which the at least one ventilation aperture is sealed to prevent ventilation of the chamber and a deployed position in which the cutting formation has broken through at least a portion of the breakable wall. The outer wall has a retaining formation which engages with the piston guide to releasably resist sliding of the hollow piston between the ventilation position and the sealed position and the deployed position. The hollow piston may have an outer wall, and said outer wall has an end within the chamber, facing the breakable wall, wherein the cutting end has a first edge having a cutting formation and a gap in said cutting formation.

The present invention provides composition, apparatus, kit and method for compounding an orally administered dosage form of at least one medicament comprising a container for mixing a crushed medicament with a gel-based carrier. The container comprises at least one chamber and at least one membrane as a separating element. The container comprises a flexible membrane, when removed or partially broken, provides a mixture of a defined dosage form of said medicament comprising the crushed medicament and said gel-based carrier. The membrane is further configured to prevent contamination, overdosing and non sanctioned abuse of active ingredient of said medicament.

A closure for dispensing one or more active agents into a container comprises a sealed or sealable chamber having a breakable wall and a hollow piston slidably mounted in a piston guide. Said hollow piston comprises an outer wall having an end in the chamber and at least one ventilation aperture. Said end has a cutting formation. Said hollow piston is slidable in the piston guide between a ventilation position in which the at least one ventilation aperture allows ventilation of the chamber and a sealed position in which the at least one ventilation aperture is sealed to prevent ventilation of the chamber and a deployed position in which the cutting formation has broken through at least a portion of the breakable wall. The outer wall has a retaining formation which engages with the piston guide to releasably resist sliding of the hollow piston between the ventilation position and the sealed position and the deployed position. The hollow piston may have an outer wall, and said outer wall has an end within the chamber, facing the breakable wall, wherein the cutting end has a first edge having a cutting formation and a gap in said cutting formation.

A bottle cap with additive supply structure, comprising a bottle cap body and a storage cap; the bottle cap body comprises a first top and a first outer skirt part; the storage cap comprises a second top and a second outer skirt part, the second top, the second external skirt and a crackable part form a sealed storage space. In the invention, the additives are placed in the storage cap, the storage cap is mounted in the mounting groove, sealing performance of the storage space is better, and the additives can be prevented from being affected by damp and going bad. The bottle cap body is provided with the crackable part, the crackable part can be opened only by knocking on the storage cap downwards during use, making the additives fall into a bottle body so as to be mixed with bottled contents.

Various aspects of this patent document relate cannabinoid anions including methods to produce cannabinoid anions, compositions comprising cannabinoid anions, containers that contain compositions comprising cannabinoid anions, and methods to consume cannabinoid anions.

Disclosed herein is a package having: a housing defining a body and a container; a frangible closure which, in combination with the body, defines a soluble compartment; a frangible closure which, in combination with the container, defines a water compartment separate from the soluble compartment; a quantity of a soluble contained within the soluble compartment; and a quantity of water contained within the water compartment and which, if mixed with the soluble contained in the soluble compartment, produces an ingestible.

A drug mixing container is provided. The drug mixing container includes a container with an opening facing upward and a cover body. An inner peripheral wall of the container includes at least one piercing structure protruding toward the opening of the container. The cover body accommodates a drug and includes a sealing film for sealing the drug in the cover body. In use, when an opening of the cover body is coupled downward to the opening of the container, the sealing film is pierced and torn by the piercing structure to make the drug in the cover body flow into the container, thereby preventing hands of an operator from being stained with the drug.

The present disclosure relates to drug delivery devices, and in particular, to drug delivery devices configured to reconstitute a lyophilized drug powder into liquid form prior to delivery into a patients body. In some embodiments, such devices include a flexible drug reservoir having a proximal reservoir component storing a liquid diluent and a distal reservoir component storing a lyophilized drug powder, wherein the two compartments are separated by a frangible seal. A compression member may be positioned above the reservoir and held up by a releasable mechanism. When released, the compression member may be driven downwards to compress the proximal compartment so as to break the frangible seal and allow the diluent to mix with the drug powder and form a liquid drug mixture, and then to eject the liquid drug mixture from the reservoir.

A disposable receptacle useful with an infant feeding system, including a pliable pouch. The pliable pouch may have a single compartment, or a pair of compartments wherein a first compartment is filled with powdered formula, and a second compartment is filled with distilled water. When compartmentalized, the compartments are separated by a burst seal designed to fail upon subjection to pressure of between about 1-3 lbs. The receptacles include a cylindrical fitment with a one-way valve removably positioned therewithin. A top seal of the pliable pouch is secured about the body of the fitment. The receptacles may be used with an infant feeding system having a support disc with an aperture to receive and secure the fitment, and a nipple having an internal chamber sized and configured to tightly and removably receive a portion of the fitment. The infant feeding system may optionally include a bottle and a securing ring.