A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

A fluid transfer device (10) includes a vial holder (23) configured to hold a vial (22). An actuator (40) is coupled to the vial holder (23) and can rotate the vial (22) between upright and inverted positions. A pump (positive or negative pressure) can pump contents out of the vial (22). Before pumping of the contents the actuator (40) rotates the vial (22) to the inverted position and after pumping of the contents the actuator (40) rotates the vial (22) to the upright position.

A fluid transfer device (10) includes a vial holder (23) configured to hold a vial (22). An actuator (40) is coupled to the vial holder (23) and can rotate the vial (22) between upright and inverted positions. A pump (positive or negative pressure) can pump contents out of the vial (22). Before pumping of the contents the actuator (40) rotates the vial (22) to the inverted position and after pumping of the contents the actuator (40) rotates the vial (22) to the upright position.

A medical delivery device (3) comprises a rod element having a stem with a longitudinal axis and a first thread arrangement, a dosage member (34) comprising a second thread arrangement and a chamber body, a dial unit (31), and a coupling structure coupling the dial unit (31) to the dosage member (34). The stem of the rod element extends into the chamber body of the dosage member (34). In a dosing status of the medical delivery device (3), the first thread arrangement of the rod element engages the second thread arrangement of the dosage member (34). Further, in the dosing status, the rod element is movable along its longitudinal axis relative to the dosage member (34) by the first thread arrangement of the rod element and the second thread arrangement of the dosage member (34) travelling along each other such that a volume of a dosage chamber in the interior of the chamber body of the dosage member (34) is varied. Still further, in the dosing status rotation of the dial unit (31) applies a torsional force to the dosage member (34) via the coupling structure, which torsional force rotates the dosage member (34) such that the second thread arrangement of the dosage member (34) and the first thread arrangement of the stem of the rod element travel along each other. The coupling structure has an overload protection mechanism (313, 314, 322, 324) configured to prevent that the torsional force applied by the dial unit (31) to the dosage member (34) exceeds a predefined threshold force.

A medical delivery device (3) comprises a rod element having a stem with a longitudinal axis and a first thread arrangement, a dosage member (34) comprising a second thread arrangement and a chamber body, a dial unit (31), and a coupling structure coupling the dial unit (31) to the dosage member (34). The stem of the rod element extends into the chamber body of the dosage member (34). In a dosing status of the medical delivery device (3), the first thread arrangement of the rod element engages the second thread arrangement of the dosage member (34). Further, in the dosing status, the rod element is movable along its longitudinal axis relative to the dosage member (34) by the first thread arrangement of the rod element and the second thread arrangement of the dosage member (34) travelling along each other such that a volume of a dosage chamber in the interior of the chamber body of the dosage member (34) is varied. Still further, in the dosing status rotation of the dial unit (31) applies a torsional force to the dosage member (34) via the coupling structure, which torsional force rotates the dosage member (34) such that the second thread arrangement of the dosage member (34) and the first thread arrangement of the stem of the rod element travel along each other. The coupling structure has an overload protection mechanism (313, 314, 322, 324) configured to prevent that the torsional force applied by the dial unit (31) to the dosage member (34) exceeds a predefined threshold force.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient.

A device for detecting postpartum hemorrhage is provided. A mat defines a proximal end and a distal end. The mat is configured to be disposed between a support and a patient and has a surface with a fluid flow region configured to direct flow of bodily fluids from the patient towards the distal end of the mat. A first detachable and optionally sealable bag is configured to receive the bodily fluids from the patient in a first operational mode of the device. A second sealable bag is configured to receive the bodily fluids from the patient in a second operational mode of the device. The second sealable bag comprises a visual volume indicator to measure the bodily fluids collected in the second sealable bag.

A capsule for dosing a substance to be administered orally, comprising:—a dosing chamber (2) for the substance;—an access route (6) for access of the substance into the chamber (2);—a valve (3) which permits/prevents the supply of the substance to the dosing chamber (2) through the access route (6);—a connection means (4) for connecting to a mouth of a container.

A capsule for dosing a substance to be administered orally, comprising:—a dosing chamber (2) for the substance;—an access route (6) for access of the substance into the chamber (2);—a valve (3) which permits/prevents the supply of the substance to the dosing chamber (2) through the access route (6);—a connection means (4) for connecting to a mouth of a container.