A system comprising one or more of a programmable encapsulation for containing and regulating the release of a medicament, an encapsulating device used by a manufacturer which encloses the medicament within a programmable encapsulation, a programming device used by a pharmacy or dispensary which programs the encapsulation with an intended patient's health data and prescription data, a consumer encapsulation storage device configured to store one or more programmable encapsulations for one or more of a patient, authenticate the identity of a patient, and dispense medicaments to the patient in accordance with the patient's prescription, and a portable reader configured to scan a programmable encapsulation and display the details of the medicament and instructions for its consumption.

A tamping assembly for a capsule filling machine is provided. The tamping assembly comprising a dosing disc provided with a plurality of sets of through vertical passages placed substantially equidistantly around the periphery thereof; a bottom plate disposed below the dosing disc, the bottom plate having an open region aligned with a carousel of the capsule filling machine disposed adjacent to the tamping assembly, and a set of apertures aligned with at-least one set of through vertical passages of the dosing disc; a plurality of sets of top tamping plungers disposed above the dosing disc, each set of top tamping plungers configured to be driven downwards for pressing a powdered product in the vertical passages from the top; and at-least one set of bottom tamping plungers disposed below the bottom plate and configured to be driven upwards for pressing the powdered product in the vertical passages from the bottom.

A system including a containment assembly for enclosing a medication container may comprise a first housing portion or interface portion having a proximal end and a distal end. The interface portion may include a housing wall which defines a channel spanning from the proximal end to the distal end. The channel may be open at the proximal and distal end. The containment assembly may further comprise only two pierceable septa configured to form a barrier to the channel. The containment assembly may further comprise a variable-volume housing portion having a variable volume chamber. The variable-volume portion chamber of the variable-volume housing portion may be in fluid communication with the distal end of the channel.

A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.

A tamping punch station for filling capsules in a capsule filling machine is described. The machine includes a rotatably drivable dosing disk with bore holes and a filling device for filling the bore holes. Tamping punches and ejection punches are held on a punch support, and vertical movement of the punch support causes the tamping punches to press filling material into the bore holes and the ejection punches to eject pellets created by the tamping punches in the bore holes. A first drive rotates the dosing disk along punches and a second drive moves the punch support. The second drive includes at least two spindle drives acting on the punch support with respectively one spindle nut and respectively one vertical drive spindle guided in the spindle nut and at least two drive motors, which drive respectively one of the spindle drives for vertical movement of the punch support.

A device for separating broken fragments of particles from the particles, comprising a floor arranged such that it receives the particles and the broken fragments, connected to a vibration device arranged such that it makes the floor undergo a vibratory movement, the floor being pierced with orifices to allow the broken fragments to pass through the orifices without allowing the particles to pass therethrough, and a ceiling arranged substantially parallel to the floor. The device further comprises an actuator arranged so as to move the ceiling between a first position in which it is located at a distance from the floor and a second position in which it is in contact with the floor such that the broken particle fragments stuck in the orifices are expelled therefrom.

A capsule closure device is for closing two-piece capsules each having a capsule upper portion and a capsule lower portion. The capsule closure device includes a capsule upper portion receiving member and a capsule lower portion receiving member. The capsule upper portion receiving member has a receiving hole and an introduction hole which is arranged coaxially relative to the receiving hole. The capsule upper portion receiving member has at the inner side thereof between the receiving hole and the introduction hole a support shoulder for supporting the capsule upper portion. The capsule upper portion receiving member has at the inner side thereof at the introduction hole at least one ventilation hole.

A comestible dosage form article for administration to a target subject, the dosage form comprising: an outer capsule comprising a first cap telescopically engageable with a first body; and an inner capsule, within the outer capsule, comprising a second cap telescopically engageable with a second body, wherein the inner capsule is inverted with respect to the outer capsule such that, in an assembled state, the second cap is proximal to the first body and distal to the first cap.

The present invention relates to a manufacturing method for softgel capsule containing solid and liquid formulations as core ingredient, wherein at least one pharmaceutical drug can be included in both solid formulation and liquid formulation. More particularly, this invention relates to a softgel capsule wherein liquid formulation, for example, solution and/or suspension as well as solid formulation, for example, tablet, pellet and/or sustained release dosage are present as core ingredient and its manufacturing method.

A minimal-amount powder metering device (1) for pharmaceutical or chemical applications, for metering powder volumes of less than 1 cm.sup.3, comprising a metering chamber (3) which is delimited by a surrounding wall (9) and which can be connected to a vacuum source (28) for suctioning powder in order to fill the metering chamber (3) with powder to be metered, filter means for retaining powder in the metering chamber (3) during a suctioning process being associated with the metering chamber (3), including the filter means are formed by the surrounding wall (9) and including at least one suction opening (12, 13) which serves to retain the powder in the metering chamber (3) and through which a vacuum can be applied to the metering chamber (3) is formed in the surrounding wall (9).