Systems and methods are provided for motion corrected wide-band pulse inversion ultrasonic imaging. A first pulse is transmitted, a second pulse is then transmitted after a delay, with the second pulse having different polarity. Echoes of the first pulse and the second pulse are received, using a reception bandwidth that enables capturing at least a portion of a fundamental portion of each pulse. The echoes are processed, and corresponding ultrasound images are generated based on processing. The processing includes determining displacement data between the first pulse echo and the echo of the second pulse for at least one structure in an imaged area; determining one or more displacement corrections based on the displacement data; applying at least one displacement correction to at least one of the first pulse echo and the echo of the second pulse; and combining the first pulse echo and the echo of the second pulse.

Disclosed is an ultrasound probe that includes an array of CMUT (capacitive micromachined ultrasound transducer) cells. Each cell includes a substrate carrying a first electrode of an electrode arrangement. The substrate is spatially separated from a flexible membrane by a gap. The flexible membrane includes a second electrode of the electrode arrangement. The ultrasound probe also includes an acoustic window over the array of CMUT cells. The ultrasound probe further includes a data storage element accessible to an external control module of the ultrasound probe. The data storage element stores configuration information for configuring an operation of the array of CMUT cells in pre-collapse or collapse mode with the external control module to optimize the effective bandwidth of the array. Also disclosed is a calibration method of the ultrasound probe, an ultrasound system and a method of operating the ultrasound system.

A Method for tissue characterization by ultrasounbd wave attenuation measurements comprising: a) transmitting at least an ultrasound pulse in a target body; b) receiving the ultrasound waves reflected by the said target body and transforming the said reflected ultrasound pulses in RF reception signals; c) extracting the envelope of the received RF signals; d) carrying out a logarithmic compression of the said extracted envelope and e) computing the propagation depth dependent attenuation coefficient of the tissues crossed by the ultrasound pulse in the target body as the slope of the line fitting the said logarithmic compressed envelope data along the penetration depth of the ultrasound pulse in the said target body.

The invention relates also to an ultrasound system for carrying out said method.

Systems and methods for improving spectral-shift methods for calculating acoustic attenuation coefficients are disclosed. Systems, methods, and apparatuses for transmitting ultrasound pulse sequences for improved signal-to-noise outside the main passband of ultrasound transducers are disclosed. Systems, methods, and apparatuses for using the echoes from the transmitted pulse sequences to calculate the attenuation coefficient are disclosed.

Systems and methods for attenuation measuring using ultrasound. In various embodiments, echo data corresponding to a detection of echoes of one or more ultrasound signals transmitted into tissue are received. The echoes can be received from a range of depths of the tissue. Spectral measurements across the range of depths of the tissue are obtained using the echo data. Attenuation characteristics of the tissue across the range of depths of the tissue can be estimated using the spectral measurements across the range of depths of the tissue. Specifically, the attenuation characteristics of the tissue can be estimated using the spectral measurements and known spectral characteristics of the one or more ultrasound signals transmitted into the tissue.

A method of operating an ultrasound diagnosis apparatus includes: acquiring a plurality of frequency band images respectively having different frequency bands based on an ultrasound signal corresponding to an object; determining weights respectively for the plurality of frequency band images based on brightness levels of regions including the object in each of the plurality of frequency band images; synthesizing the plurality of frequency band images based on the weights for the plurality of frequency band images; and displaying a synthetic ultrasound image of the object, generated as a result of the synthesizing.

An ultrasound system (1) is disclosed that comprises a probe (10) including an array (110) of CMUT (capacitive micromachined ultrasound transducer) cells (100), each cell comprising a substrate (112) carrying a first electrode (122), the substrate being spatially separated from a flexible membrane (114) including a second electrode (120) by a gap (118); and a bias voltage source (45) coupled to said probe and adapted to provide the respective first electrodes and second electrodes of at least some of the CMUT cells with a monotonically varying bias voltage including a monotonically varying frequency modulation in a transmission mode of said probe such that the CMUT cells are operated in a collapsed state and transmit at least one chirped pulse during said transmission mode. Such a system for instance may be an ultrasound imaging system or an ultrasound therapeutic system. An ultrasonic pulse generation method using such as system is also disclosed.

A beamforming system and method is disclosed comprising a hybrid multi-measurement unit or process that can encode or embed broadband signals in a low dimensional encoding subspace such as a Slepian subspace. The direction-of-arrival of the plane wave signals, encoded with the low dimensional embedding, can be used to provide a spatially sampled signal to a front-end mixed-signal circuitries substantially reduced hardware for beamforming systems. The beamforming array has a finite array aperture to which a temporal snapshot of the signal can be acquired and then processed as a set of samples from a time-limited bandlimited sequence.

An ultrasound system is disclosed. Embodiments in accordance with the present invention include a transducer configured to acquire pulse-echo data at each transmit frequency bandwidth of interest. In addition, a bandpass filter is configured to receive a signal of the pulse-echo data, wherein the signal is bandpass-filtered over a plurality of frequencies. Further, a processor is configured to calculate a spatial coherence of the bandpass-filtered signal. The spatial coherence of the signal is calculated in a spatial domain or a frequency domain. The spatial coherence is used to predict target conspicuity. The processor selects a preferred frequency based on and, preferably, to realize, the target conspicuity.

Disclosed is an ultrasound probe (10) including an array (110) of CMUT (capacitive micromachined ultrasound transducer) cells (100), each cell comprising a substrate (112) carrying a first electrode (122) of an electrode arrangement, the substrate being spatially separated from a flexible membrane (114) including a second electrode (120) of said electrode arrangement by a gap (118); an acoustic window (140) over the array of CMUT cells; and a data storage element (150) accessible to an external control module of the ultrasound probe. The data storage element stores configuration information for configuring an operation of the array of CMUT cells in pre-collapse or collapse mode with the external control module to optimize the effective bandwidth of the array. Also disclosed is a calibration method of the ultrasound probe, an ultrasound system and a method of operating the ultrasound system.