Disclosed in the present application is an ultrasound contrast enhanced imaging method, comprising: transmitting unfocused waves in a plurality of angles to a target region containing microbubbles; receiving echo signals of the unfocused waves; selecting echo signals corresponding to at least some of the plurality of angles from the echo signals; generating contrast enhanced image according to the selected echo signals, performing color-coding on the contrast enhanced image, and displaying same. Also disclosed in the present application is an ultrasound imaging system.

The present disclosure relates to localization of bleeds (e.g., arterial bleed events) using a limited or minimal number of ultrasound scans. In one implementation, Doppler ultrasound is used to measure blood flow velocities in a one-dimensional (1D) arterial tree model to determine the location and size of bleed. In a second implementation, ultrasound measured waveforms for blood flow velocity and vessel cross-sectional area are de-composed. The features in the de-composed waveforms are then used to locate the bleed using a trained algorithm.

A method of power Doppler imaging may include receiving a plurality of temporally sequential frames of wall-filtered power Doppler signals, wherein the plurality of temporally sequential frames includes at least one previously adjusted output frame. The method may further include adjusting at least one of the plurality of temporally sequential frames to produce an adjusted output frame and generating a power Doppler image based, at least in part, on the adjusted output frame. The adjusting may involve filtering the plurality of temporally sequential frames to suppress the high spatial frequency and high temporal frequency content to produce the adjusted output frame.

Devices, systems, and methods of imaging a blood vessel are provided. For example, the method can include obtaining fluoroscopic image data of a region of interest in a blood vessel using an x-ray source; obtaining intravascular ultrasound (IVUS) data at a plurality of positions across the region of interest using an IVUS component disposed on an intravascular device; processing the fluoroscopic image data and IVUS data, including: determining, using the fluoroscopic image data, a position of the intravascular device with respect to the x-ray source at each of the plurality of positions across the region of interest; co-registering the fluoroscopic image data and the IVUS image data; and generating, a model of the region of interest including position information of a border of a lumen of the blood vessel at each of the plurality of locations; and outputting a visual representation of the model of the region of interest.

An ultrasound imaging system includes a transducer array (102) with a plurality of transducer elements (106) configured to transmit an ultrasound signal, receive echo signals produced in response to the ultrasound signal interacting with stationary structure and flowing structure, and generate electrical signals indicative of the echo signals. The system further includes a beamformer (112) configured to process the electrical signals and generate sequences, in time, of beamformed data. The system further includes a filter (118) configured to process the beamformed data, and remove or replace a set of frequency components based on a threshold, producing corrected beamformed data. The system further includes a flow processor (120) configured to estimate a velocity of flowing structure from the corrected beamformed data. The system further includes a rendering engine (224) configured to display the flow velocity estimate on a display (124).

An ultrasound diagnosis apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to sequentially obtain eigenvalues of a correlation matrix of a scan range, the correlation matrix being obtained from a data sequence of reflected-wave data in mutually the same position acquired by performing an ultrasound scan on the scan range formed with a plurality of scanning lines. The processing circuitry is configured to determine a filter coefficient to be applied to a Moving Target Indicator (MTI) filter, on a basis of the plurality of eigenvalues obtained at mutually-different points in time.

Devices, systems, and methods of imaging a blood vessel are provided. For example, the method can include obtaining fluoroscopic image data of a region of interest in a blood vessel using an x-ray source; obtaining intravascular ultrasound (IVUS) data at a plurality of positions across the region of interest using an IVUS component disposed on an intravascular device; processing the fluoroscopic image data and IVUS data, including: determining, using the fluoroscopic image data, a position of the intravascular device with respect to the x-ray source at each of the plurality of positions across the region of interest; co-registering the fluoroscopic image data and the IVUS image data; and generating, a model of the region of interest including position information of a border of a lumen of the blood vessel at each of the plurality of locations; and outputting a visual representation of the model of the region of interest.

An ultrasound diagnostic apparatus 1 includes: a data acquisition unit 3 that repeatedly transmits an ultrasound beam to a subject a plurality of times in a range over a plurality of scanning lines to acquire a time-series data string of reflected waves from the subject; an analysis target data selection unit 7 that estimates the amount of relative positional deviation of a scatterer of the subject which is included in the time-series data string and excludes time-series data satisfying an exclusion condition based on the amount of positional deviation of the scatterer from the time-series data string to select analysis target data; an MTI filter unit 8 that removes a clutter component from the analysis target data; and a blood flow information estimation unit 9 that analyzes the analysis target data from which the clutter component has been removed to estimate blood flow information of the subject.

Systems and methods for color Doppler imaging in an ultrasound imaging system are disclosed herein. An ultrasound imaging system includes color Doppler imaging circuitry. The color Doppler imaging circuitry is configured to estimate flow parameters. The imaging circuitry includes a radio frequency (RF) demodulator configured to produce in-phase and quadrature components of an ultra-sound data vector. The RF demodulator includes a table in memory that stores interleaved sine and cosine values. The RF demodulator maintains an index value for the table having higher precision than is used to index the table. The RF demodulator rounds the index value for each access of the table. Each table access retrieves a sine value and a cosine value.

Described herein are methods and apparatus for increasing sensitivity of ultrasound imaging of fluid flow in an object of interest. Ultrasound imaging of blood perfusion can be performed without contrast enhancement. Embodiments include transforming a spatiotemporal echo data array into a three-dimensional perfusion data array having a spatial dimension, a slow-time dimension, and a frame-time dimension, and filtering the perfusion data array with an eigen passband clutter filter. The clutter filter can increase sensitivity and utility of ultrasound imaging of fluid flow. In some aspects, the method can yield blood flow signal power and perfusion values well separated from tissue clutter. In an example, enhancements to ischemic tissue perfusion maps in a murine model are shown.