The present disclosure provides an imaging system and method for nuclear medicine imaging. The imaging system may include a detector and a collimator. The detector may be configured to detect photons. The collimator may have at least two sets of pinholes. The at least two sets of pinholes may include a first set of first pinholes and a second set of second pinholes. Each second pinhole of the second set of second pinholes may be equipped with a filter configured to filter the photons.

A radiation diagnostic device according to an aspect of the present invention includes a first detector, a second detector, and processing circuitry. The first detector detects Cherenkov light that is generated when radiation passes. The second detector is disposed to be opposed to the first detector on a side distant from a generation source of the radiation, and detects energy information of the radiation. The processing circuitry specifies Compton scattering events detected by the second detector, and determines an event corresponding to an incident channel among the specified Compton scattering events based on a detection result obtained by the first detector.

Provided herein are compounds that are broad-spectrum protein kinase binding agents, detectable tracers comprising such compounds, and method of use thereof for the detection of protein kinases.

A position-signal processing method for flat panel gamma imaging probe includes a modeling phase and a use phase. In the modeling phase, a weight direction for an imaging detector is defined, position centers and weight ratios of the imaging detector in the weight direction are utilized to obtain a distribution graph of the weight ratios to the position centers, and curve fitting is performed upon the distribution graph to obtain a position estimation curve. In the use phase, the position estimation curve is utilized to derive a position estimation value of a probe trigger event in a 2D crystal diagram, a position value of the probe in the 2D crystal diagram with respect to the position estimation value of the probe trigger event is obtained, and a crystal code is located in a crystal code look-up table for the position value of the probe in the 2D crystal diagram.

Various noncollimated single photon emission computed tomography (SPECT) technologies are described herein. An example device includes an array of detectors configured to detect a flux of first photons transmitted from a field of view (FOV) over time. The device also includes an attenuator disposed between the array of detectors and the FOV. The attenuator is configured to move over time and to attenuate second photons emitted from the source. In various implementations, the attenuator is not a collimator. Based on the fluxes of the first photons detected by the detectors, and the position of the attenuator over time, an imaging system may be configured to generate an image of the FOV.

A PET detector having some light guides not cut, comprising a light guide bar array unit having some light guides not cut. The light guide bar array unit is in the form of an array consisting of a plurality of parallel light guide bars (2), and adjacent light guide bars (2) in some regions of the light guide bar array unit and a reflective material (4) between every two light guide bars are replaced with a light guide three-dimensional block having the identical shape and volume, taken as a whole. The detector sequentially comprises a layer formed by a scintillating crystal array unit, a layer formed by the light guide bar array unit, and a layer formed by a silicon photomultiplier array unit in an arrangement order.

Provided is a PET detector for reducing the number of silicon photomultipliers in use, which is characterized in that: the detector comprises layers respectively formed by a scintillation crystal array unit and a silicon photomultiplier (4) array unit, the scintillation crystal array unit and the silicon photomultiplier (4) array unit are rectangular cross sections in plan view, and the scintillation crystal array unit and the silicon photomultiplier (4) array unit have the same area of the rectangular cross sections in plan view; the scintillation crystal array unit consists of a plurality of scintillation crystal strips (1) parallel to each other, free of gaps and attached to each other on sides, the scintillation crystal strips (1) are all cuboids with uniform length, width and height; the silicon photomultiplier (4) array unit is an array assembly, which is formed by M silicon photomultiplier (4) arrays and has the rectangular cross section in plan view.

The invention relates to a hybrid medical PET-SPECT/MR imaging device comprising at least one scintillating crystal and at least one module for detecting radiation which contains at least one matrix of photodetectors and an electronics section, such that said module has a mechanical structure, the external, internal or both surfaces of which are divided into at least two sections, of which at least one is coated in graphene, and the rest in non-ferromagnetic conductive material, or all the sections are coated in graphene, and such that the coating forms a Faraday cage. The invention also relates to a shielding against radiofrequency for a medical imaging device, comprising a graphene coating, which is continuous or in bands, on all the faces of the mechanical structure of the detection module of the device, or a graphene coating, continuous or in bands, on at least one face, combined with a coating of non-ferromagnetic conductive materials on the remaining faces, and said shielding forming a Faraday cage.

A surgical guidance system offering different levels of imaging capability while maintaining the same hand-held convenient small size of light-weight intra-operative probes. The surgical guidance system includes a second detector, typically an imager, located behind the area of surgical interest to form a coincidence guidance system with the hand-held probe. This approach is focused on the detection of positron emitting biomarkers with gamma rays accompanying positron emissions from the radiolabeled nuclei.

A device for generating one or more images of a source distribution of a gamma radiation field in the near and far field can include a detector system that includes several synchronized detectors for detecting radiation, system electronics that registers coincidence events, a data acquisition system that stores the measurement data of the coincidence events, and an analysis unit that performs an image reconstruction, which reconstructs one or more images of the source distribution of the radiation field.